Effects of colchicine adjuvant therapy on disease control, serum NALP3, sICAM-1, MMP-9 and MMP-13 in patients with coronary heart disease and acute gout attack.

Background: To investigate the impact of colchicine adjuvant therapy on disease control and serum levels of nucleotide-binding oligomerization domain-like receptor (NALP) 3, soluble intercellular adhesion molecule (sICAM)-1, matrix metalloproteinase (MMP)-9, and MMP13 in patients with coronary heart disease (CHD) complicated by acute gout attacks.

Methods: Ninety-two patients with CHD and acute gout attacks admitted to our hospital from October 2021 to January 2023 were randomly divided into an observation group and a control group, with 46 patients in each group. The control group received conventional treatment, while the observation group received colchicine adjuvant therapy on top of the control group's treatment for 7 days.

Atractylenolide I ameliorates post-infectious irritable bowel syndrome by inhibiting the polymerase I and transcript release factor and c-Jun N-terminal kinase/inducible nitric oxide synthase pathway.

Objective: To explore the therapeutic effect and target of atractylenolide I (AT-I) on post-infectious irritable bowel syndrome (PI-IBS) rats.

Methods: Therefore, the preliminarily mechanism of AT-I in anti-PI-IBS were first predicted by network pharmacology and molecular docking, then the possible signaling pathways were systematically analyzed. Finally, the potential therapeutic targets and possible signaling pathways of AT-I on PI-IBS in Sprague-Dawley (SD) rat model were verified by experiments.

An updated systematic review, meta-analysis and trial sequential analysis of the efficacy and safety of en bloc transurethral resection vs. conventional transurethral resection for non-muscle-invasive bladder tumor.

Objective: En bloc transurethral resection of bladder tumor (ERBT) for non-muscular invasive bladder tumor (NMIBC) has been used in clinical practice, but its efficacy and safety have not been conclusional. We aimed to evaluate the efficacy and safety of ERBT and conventional transurethral resection of bladder tumor (cTURBT) for NMIBC.

Methods: Randomized controlled trials (RCTs) comparing ERBT and cTURBT in the treatment of NMIBC were searched in Pubmed, Embase, Clinicaltrials.

Global CO uptake by cement materials accounts 1930-2023.

The majority of the carbon footprint of the cement industry originates from the decomposition of alkaline carbonates during clinker production. Recent studies have demonstrated that calcium oxides and other alkaline oxides in cement materials can sequester CO through the carbonation process and partially offset the carbon emissions generated during cement production. This study employs a comprehensive analytical model to estimate the CO uptake via hydrated cement carbonation, including concrete, mortar, construction waste, and cement kiln dust (CKD), covering major cement production and consumption regions worldwide from 1930 to 2023.

The long-term impact of debt relief for indigent defendants in a misdemeanor court.

US courts regularly assess fines, fees, and costs against criminal defendants. Court-related debt can cause continuing court involvement and incarceration, not because of new crimes, but because of unpaid financial obligations. We conducted an experiment with 606 people found guilty of misdemeanors in Oklahoma County, Oklahoma.

Optimization of Preparation Technology for PET-Based Carbon Dots by Response Surface Method and Its Application.

The preparation of polyethylene terephthalate(PET)-based Carbon Dots (PET-CDs) using one-step hydrothermal method with PET waste, pyromellitic acid (PMA) and ammonia (NH·HO) as precursors is a high-value utilization strategy for PET waste, offering significant application potential. To achieve efficient recycling of PET waste, response surface methodology was adopted for to optimize the precursor ratio during the synthesis of PET-CDs with fluorescence quantum yield (QY) as the key performance indicator. The optimal preparation conditions were determined to be: 1.

Mothering While Sick: Poor Maternal Health and the Educational Attainment of Young Adults.

At a time when educational attainment in young adulthood forecasts long-term trajectories of economic mobility, better health, and stable partnership, there is more pressure on mothers to provide labor and support to advance their children's interests in the K-12 system. As a result, poor health among mothers when children are growing up may interfere with how far they progress educationally. Applying life course theory to the National Longitudinal Study of Adolescent to Adult Health to investigate this possibility, we found that young adults were less likely to graduate from college when raised by mothers in poor health, especially when those mothers had a college degree themselves.

Comparative study of CT and MR guided microwave ablation in the treatment of para-vascular VX2 liver tumor model in rabbits.

Objective： To analyze the efficacy of microwave ablation (MWA) guided by computed tomography (CT) and 1.5T magnetic resonance (MR) in the treatment of VX2 para-vascular liver tumor model in rabbits. Materials and Methods Sixty para-vascular VX2 liver tumor models in rabbits were randomly divided into CT-guided microwave ablation group (CT group, n=35) and MR-guided microwave ablation group (MR group, n=35).

Clinical indications for radical resection of odontogenic keratocyst: A systematic review.

The aim of this study was to identify clinico pathological indications for radical resection of odontogenic keratocysts (OKCs) in the literature and formulate clinical guidelines for the management of OKCs based on these findings. A systematic review of the literature was undertaken in September 2021 in PubMed/Medline, Scopus, Web of Science, Google Scholar, and Cochrane databases. The following MeSH Keywords terms were used in the search strategies: (odontogenic keratocyst) OR (keratocystic odontogenic tumor) OR (primordial cyst) AND (treatment) OR (Radical resection) OR (Resection of OKC) OR (Treatment methods).

Benefit analysis of multi-approach biomass energy utilization toward carbon neutrality.

To reduce greenhouse gas (GHG) emissions, biomass has been increasingly developed as a renewable and clean alternative to fossil fuels because of its carbon-neutral characteristics. China has been investigating the rational development and use of bioenergy for developing its clean energy and achieving carbon neutrality. Substituting fossil fuels with multi-source and multi-approach utilized bioenergy and corresponding carbon reduction in China remain largely unexplored.

Developing and Implementing In-Person and Virtual SoilSHOPs in Atlanta, Georgia, as a Community-Engaged Approach to Screen and Prevent Soil Lead Exposure.

Urban agriculture presents the opportunity for increased availability of local, fresh foods; however, exposure to lead soil contamination can occur through gardening in urban environments. Through a community-engaged partnership, we implemented Soil Screening, Health, Outreach and Partnerships (soilSHOPs), in-person and virtually, to screen soils for lead in Atlanta, Georgia. These soilSHOPs inform best practices for increasing awareness about lead exposure and grounding interventions in residents' lived experiences and also led the US Environmental Protection Agency to identify a Superfund site.

Fabrication of Functionalized UiO-66 Anchored on Disorderly Layered Clinoptilolite via Surfactant-Assisted Induction for Selective Adsorption of CO and CH.

The amine (NH)-functionalized UiO-66 was successfully anchored on disorderly layered clinoptilolite (CP) via surfactant (poly(ethylene glycol) (PEG) and poly(vinylpyrrolidone) (PVP))-assisted induction. The structural features and physicochemical parameters of the resultant UiO-66-on-CPs were characterized by powder X-ray diffraction (XRD) patterns, scanning/transmission electron microscopy (SEM/TEM) images, Fourier transform infrared (FT-IR) spectra, N sorption isotherms, and small-angle X-ray scattering (SAXS) patterns. The results demonstrated that the growth of UiO-66-NH nanoparticles facilitated the disorder degree of the crystal plane of CP along the a-axis, while the addition of PEG in the hydrothermal synthesis system of CP was conducive to the formation of a flower-like microstructure and the introduction of PVP was beneficial to the nucleation and growth of UiO-66-NH nanoparticles with a small size (40 nm) on the surfaces of the obtained CP-PEG lamellas.

[Evaluation of climate regulation service at prefecture-level city: A case study of Fuzhou City, China].

Ecosystem services are the bridge between ecosystem functions and human welfare. Climate regulation service (CRS) has an extremely important role in ecosystem services. It is important to conduct a comprehensive assessment based on the whole process of CRS occurrence for scientific assessment of ecosystem services.

The Expression of the Long Noncoding RNA AFAP1-AS1 in Laryngeal Carcinoma Affects the Proliferation, Invasion, Migration, and Apoptosis of TU212 Cell Line.

Background: lncRNA AFAP1-AS1 has been linked to the pathogenesis of a wide range of tumors. Nevertheless, whether it plays a role in laryngeal carcinoma (LC) remains unclear.

Methods: Twenty-nine pairs of LC and related normal tissues were collected for the detection of lncRNA AFAP1-AS1 using qRT-PCR.

[Contribution of straw disposal to carbon source and sink under the framework of carbon neutrality].

Exploring the spatio-temporal variation characteristics of carbon source and carbon sink under different disposal methods of crop straw is of great significance for optimizing the utilization policy of crop straw resources in China and realizing the goal of maximizing carbon emission reduction and carbon neutralization. Based on data from National Statistical Yearbook, we examined the changing trends of both the amount and value of carbon emission, carbon emission reduction, carbon sink enhancement under different crop straw disposal methods in 31 provinces of Chinese mainland. The results showed that the mean annual carbon emissions of straw burning in China from 2008 to 2019 were 8.

Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding proteins cleavage-activating protein ubiquitination.

Objectives: This study was aimed to explore whether and how berberine suppresses colon cancer cell metastasis via lipid modulation.

Methods: Lipid accumulation was measured by an oil red O staining kit. The expression of proteins and message RNA was detected by Western blot and quantitative real-time PCR.

Incomparable Punishments: How Economic Inequality Contributes to the Disparate Impact of Legal Fines and Fees.

Low-level misdemeanor and traffic violations draw tens of millions of people into local courts to pay fines and fees each year, generating billions of dollars in revenue. We examine how standardized legal fines and fees for low-level charges induce disparate treatment and result in disparate impact. Using a mixed-methods approach that incorporates administrative court records as well as interviews with criminal defendants from Texas, we find that although the majority of defendants readily pay for and conclude their case, African American, Latinx, and economically disadvantaged defendants spend disproportionate amounts of money and time resolving theirs.

Comparison of mesoporous fractal characteristics of silica-supported organocatalysts derived from bipyridine-proline and resultant effects on the catalytic asymmetric aldol performances.

Three kinds of the bipyridine-proline chiral ligands as highly active species were successfully introduced on Zn-modified mesoporous silica nanomaterials (BMMs, MCM-41, and SBA-15) the covalent attachment and coordination methods. Their microstructural features and physicochemical properties were extensively characterized XRD patterns, SEM/TEM images, TGA profiles, FT-IR and UV-Vis spectra. In particular, their fractal features, the pair distance distribution function, and the Porod plots were evaluated thoroughly on the basis of the SAXS data.

Educating the Future Environmental Health Workforce During COVID-19: Developing a Virtual Curriculum for Navajo Student Interns Using the Environmental Health and Land Reuse Certificate Program.

Beginning in 2016, the Agency for Toxic Substances and Disease Registry (ATSDR) and the National Environmental Health Association (NEHA) launched a partnership to create a free online course with the goal of building capacity within communities to help remediate and redevelop brownfields sites. Brownfields are land reuse sites often contaminated by harmful chemicals or redeveloped without proper environmental oversight. Due to their potentially hazardous status, brownfields sites can lead to harmful exposures in humans while accentuating and often exacerbating socioeconomic disparities within their communities.