Treatment of severe skeletal open bite deformity in patients with Möbius syndrome: a report of 3 cases.

Purpose: To investigate the treatment of severe skeletal open bite deformities in Möbius syndrome patients.

Materials And Methods: Three patients aged 17 to 24 years (2 male patients and 1 female patient) with Möbius syndrome were evaluated and treated with preoperative orthodontics, orthognathic surgery, and postoperative orthodontic management. One patient was treated by bilateral V osteotomies of the mandibular body and one patient with bilateral V osteotomies of the mandibular body plus a Le Fort I osteotomy.

Using flow to switch the valency of bacterial capture on engineered surfaces containing immobilized nanoparticles.

Toward an understanding of nanoparticle-bacterial interactions and the development of sensors and other substrates for controlled bacterial adhesion, this article describes the influence of flow on the initial stages of bacterial capture (Staphylococcus aureus) on surfaces containing cationic nanoparticles. A PEG (poly(ethylene glycol)) brush on the surface around the nanoparticles sterically repels the bacteria. Variations in ionic strength tune the Debye length from 1 to 4 nm, increasing the strength and range of the nanoparticle attractions toward the bacteria.

Comparative study of different osteotomy modalities in maxillary distraction osteogenesis for cleft lip and palate.

Purpose: Conventional maxillary distraction osteogenesis and anterior maxillary segmental distraction were applied in the treatment of severe maxillary hypoplasia secondary to cleft clip and palate. The aim of the present study was to compare the difference between these 2 osteotomy modalities used for rigid external distraction.

Patients And Methods: Ten patients with severe maxillary hypoplasia secondary to CLP were enrolled in our study.

The Haptic Deictic System-HDS: Bringing Blind Students to Mainstream Classrooms.

Mathematics instruction and discourse typically involve two modes of communication: speech and graphical presentation. For the communication to remain situated, dynamic synchrony must be maintained between the speech and dynamic focus in the graphics. In sighted people, vision is used for two purposes: access to graphical material and awareness of embodied behavior.

Osteogenic response of mesenchymal stem cells to continuous mechanical strain is dependent on ERK1/2-Runx2 signaling.

Mechanical stimuli are responsible for bone remodeling during orthodontic tooth movement. The role of mechanical stimulation in the regulation of the fate of bone mesenchymal stem cells (BMSCs) is of interest in bone regeneration and tissue engineering applications. However, the signaling pathway involved in strain-induced biochemical events in BMSCs is not well established and can be controversial.

[Research on periodontal changes on the compression side during rapid tooth movement into newly distracted bone].

Purpose: To investigate periodontal remodeling mechanism on the compression side during early tooth movement into newly distracted bone.

Methods: Ten male Beagle dogs were selected. Distraction osteogenesis was performed on randomized side as experimental group, while the fourth premolars were extracted on the other side as control group.

[Clinical study of ramus implant anchorage for mandibular arch distalization].

Purpose: To evaluate the efficiency of ramus implant anchorage for mandibular arch distalization, and determine the feature of tooth movement.

Methods: Six patients were selected to distalize mandibular arch with ramus implant anchorage. Position changes of mandibular first molars and incisors were measured in sagittal and vertical direction to evaluate the amount of molar and incisor distalization and character of tooth movement.

Bacterial adhesion on hybrid cationic nanoparticle-polymer brush surfaces: ionic strength tunes capture from monovalent to multivalent binding.

This paper describes the creation of hybrid surfaces containing cationic nanoparticles and biocompatible PEG (polyethylene glycol) brushes that manipulate bacterial adhesion for potential diagnostic and implant applications. Here, ∼10 nm cationically functionalized gold nanoparticles are immobilized randomly on negative silica surfaces at tightly controlled surface loadings, and the remaining areas are functionalized with a hydrated PEG brush, using a graft copolymer of poly-l-lysine and PEG (PLL-PEG), containing 2000 molecular weight PEG chains and roughly 30% functionalization of the PLL. The cationic nanoparticles attract the negative surfaces of suspended Staphylococcus aureus bacteria while the PEG brush exerts a steric repulsion.

[Establishment of a dog model of orthodontic tooth moving into newly distracted bone].

Purpose: This study was to establish an animal model of tooth moving into newly distracted bone after mandibular distraction osteogenesis in Beagle dog.

Methods: Eight Beagle dogs were selected in this study four dogs (experiment group) underwent 10 mm of bilateral mandibular distraction osteogenesis. After 0-week consolidation periods, the bilateral third premolars were moved distally into the regenerated bone with 150g orthodontic force for 8 weeks.

Sequential maxillary bifocal transport distraction osteogenesis after radiotherapy.

Maxillary defects secondary to ablative surgery are common, and functional maxillary reconstruction is challenging. Adjuvant radiotherapy further complicates reconstructive surgical planning. In this article, successful functional reconstruction of a partial maxillary defect was achieved using segmental osteotomy, sequential bifocal distraction osteogenesis, and prosthodontic treatment.

Traumatic temporomandibular joint ankylosis: our classification and treatment experience.

Objective: This article studies the classification of traumatic temporomandibular joint (TMJ) ankylosis based on coronal computed tomographic (CT) scan and presents our treatment experience in the TMJ division of Shanghai Ninth People's Hospital.

Patients And Methods: From 2001 to 2009, 130 patients diagnosed with TMJ ankylosis were treated in the TMJ division. Among them, 84 patients with 124 joint injuries caused by trauma were treated first by our group of surgeons and were included in this study.

[Exploration on the sliding mechanism of implant anchorage assisted self-ligating appliance].

Purpose: To investigate non-extraction treatment of borderline cases through analysis of cases treated by maxillary implant anchorage assisted self-ligating appliance.

Methods: Twenty adult patients with moderate-crowding malocclusion were reviewed. The patients were divided into 2 groups.

Intracranial fixation pin migration: a complication of external Le Fort III distraction osteogenesis in Apert syndrome.

External distraction osteogenesis has long been used in treatment of congenital midface hypoplasia. Distraction osteogenesis is associated with lower relapse rate and less complications compared with standard Le Fort III osteotomy. General complications in using rigid external distraction include localized infection, loosening of pins, and pin displacement.

Reconstruction of partial maxillary defect with intraoral distraction osteogenesis assisted by miniscrew implant anchorages.

Objective: The paper reports a custom-made trifocal transport distractor assisted by miniscrew implant anchorages (MIAs) used to reconstruct maxillary defects and evaluates the clinical results of function and esthetics.

Study Design: Eight patients aged 19-43 years who suffered regional maxillary defects were involved. Each one underwent segmental bone excision of the maxilla and distraction osteogenesis (DO) in the defect region by a custom-made interoral 3-dimensional distractor which was activated by orthodontic elastic force assisted by MIAs at the rate of View Article and Find Full Text PDF

[The role of CBCT in evaluation of alveolar bone state during orthodontic-periodontal treatment].

Purpose: To evaluate the role of cone beam computed tomography (CBCT) in evaluation of alveolar bone state during orthodontic-periodontal treatment.

Methods: Twenty patients with periodontal disease seeking for orthodontic-periodontal therapy were selected. The first stage of orthodontics included alignment and leveling arches (treatment) and the average period was 6 months.

[Valproic acid induce the expression of MICA antigen in human lung cancer cells and promote the NK killing effects on the cells].

Objective: To investigate the effect of valproic acid (VPA) on MICA gene expression in human lung carcinoma cell lines: A549, SP-CA-1, NCIH446.

Methods: Different concentration of VPA were applied to treat A549, SP-CA-1, NCIH446 cells respectively and the untreated cells as the control. The effect of the VPA on the cells were observed.

Calcium regulating the polarity: a new pathogenesis of aphthous ulcer.

Aphthous ulcer is one of the most common oral conditions. Although many etiological factors have been presented, its precise cause remains unclear. Not only is calcium an integral part of the teeth and bones, but it is a second messenger involving in many physiological processes.

[Human leucocyte antigen-DR expression on CD(14)(+) monocytes and its relationships with multiple organ dysfunction syndrome in severe sepsis].

Objective: To explore the changes of CD(14)(+) monocyte human leucocyte antigen DR (HLA-DR) and their relationship with multiple organ dysfunction syndrome (MODS) in severe sepsis.

Methods: Ninety-one patients with a definite diagnosis of severe sepsis in the intensive care unit (ICU) were included. CD(14)(+) monocyte HLA-DR levels were detected by flow cytometry on the first, 4th and 7th days of the study, and Marshall scores and prognosis on day 28 were evaluated.

Mia-assisted orthodontic treatment for dental malocclusion secondary to periodontal disease.

In contemporary dental care, an increasing number of adult patients with periodontal disease are seeking orthodontic treatment. Achieving optimal results in such adult patients is difficult because decreased posterior tooth anchorage is risky. This case report demonstrates the use of miniscrew implant anchorage (MIA) in a Chinese male 21 years 5 months of age with maxillary and mandibular anterior dental spacing, bimaxillary protrusion, and severe bone loss caused by periodontal disease.

[Combined surgical and orthodontic treatment of severe maxillary anterior teeth and dentoalveolar bone protrusion].

Purpose: The purpose of this study is to investigate the outcome and stability of combined surgical and orthodontic treatment of severe maxillary anterior teeth and dentoalveolar bone protrusion.

Methods: Twenty-eight adults with severe bimaxillary protrusion were included.Presurgical orthodontic treatment coordinated axis of upper anteriors and dentoalveolar bone.

Undulated multicompartment cylinders by the controlled and directed stacking of polymer micelles with a compartmentalized corona.

Like a bamboo rod: Long, bamboo-like undulated cylinders with distinct branch points and end groups (see picture) were obtained by the stacking of block terpolymer micelles that contain a fluorinated polybutadiene core and a compartmentalized corona of poly(4-tert-butoxystyrene) and poly(tert-butyl methacrylate). Stacking of the polymer micelles, which can be reversed, occurred when the solvent was changed from dioxane to ethanol.

Extrauterine growth retardation in premature infants in Shanghai: a multicenter retrospective review.

Intrauterine growth retardation (IUGR) represents the degree of body growth and development decided by genes and by placental function. Extrauterine growth retardation/restriction (EUGR) refers to severe nutritional deficits during the first weeks of life that result in growth that is less than expected based on intrauterine growth rates (growth values < or =10th percentile of intrauterine growth expected in accordance with the estimated gestational age). The deficits affect not only weight but also head circumference and height.

[Change of serum endogenous digitalis-like substance undergoing cardiopulmonary bypass].

Objective: To investigate the plasma concentrations and cardiac effects of endogenous digitalis-like substance (EDLS) before and after cardiopulmonary bypass (CPB).

Methods: 29 adults patients with NYHA II - IV, who suffered from congenital and acquired heart diseases, were included in this study. The plasma EDLS levels were determined by radioimmunoassay before and at the end of CPB, 2 h, 6 h, 24 h and 3 days after operation.