Publications by authors named "Bing Bi"

Article Synopsis
  • Hematopoiesis, essential for organism health, can be studied using Drosophila (fruit flies) due to similar regulatory processes found in vertebrates, primarily occurring in the larval lymph gland with various specialized zones.
  • The study focuses on the role of Rab1 in maintaining β-integrin trafficking in hemocytes and lymph gland cells, highlighting its importance in cell adhesion and the potential disruption caused by Rab1 dysfunction.
  • Findings reveal that Rab1 impairment results in mislocalized β-integrin, affecting lamellocyte differentiation and overall hematopoietic homeostasis, with evidence showing interactions with the adhesion protein DE-cadherin and the Q-SNARE protein Syntaxin
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Extraosseous MDP uptake was not uncommon on the bone scintigraphy. When the extraosseous activity is overlapping the bones, it might cause difficulty in interpreting the result when only static images were acquired. Here we report 2 cases that abnormal MDP activity overlapping the bones on planar images, which were confirmed as soft tissue lesions by SPECT/CT or CT imaging.

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Article Synopsis
  • Breast cancer, especially estrogen receptor-positive (ER) subtype, poses significant treatment challenges due to current therapies' side effects; this study investigates Chrysin, a natural flavonoid with potential benefits for ER breast cancer, using mesoporous dopamine nanoparticles (mPDA) for improved delivery and efficacy.
  • * Researchers synthesized and characterized Chrysin-loaded mPDA nanoparticles, evaluated their effectiveness in animal models, and utilized network pharmacology to understand Chrysin's mechanisms and validate findings through gene expression analysis.
  • * Results showed that Chrysin@mPDA nanoparticles effectively released the drug when exposed to laser irradiation, leading to reduced tumor volume and weight, decreased estrogen receptor-positive cells, and increased immune cell infiltration, demonstrating promise for
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Glutamine-fructose-6-phosphate transaminase (GFAT) has been reported to regulate the hexosamine biosynthetic pathway as the first rate-limiting enzyme. As a key enzyme that catalyzes the substrate of glycosylation modification, which has a wide-ranging effect on cellular functions. However, there are few studies on the relationship between GFAT and chitin metabolism in insects.

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Biochemistry is an important fundamental course of biology related majors, and has the characteristics of speedy development, massive information, sound theoretical basis and feasible applicability. It is difficult for students to learn well in the process of teaching. In addition, the experimental course lacks integrity, comprehensiveness and design experiments.

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Lymantria dispar asiatica is a globally distributed herbivorous pest. Avermectin is a highly effective, broad-spectrum insecticide. In this study, fourth instar L.

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Sodium pheophorbide a (SPA) is a natural photosensitizer. To explore its antifungal activity and mechanism, we studied its inhibitory effects on spore germination and mycelial growth of Pestalotiopsis neglecta. We used sorbitol, 2-thiobarbituric acid (TBA) and electron microscopy to determine its effects on cell wall integrity, cell membrane lipid peroxidation and mycelial morphology.

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Metalloenzyme SODs play important roles in insects dealing with environmental stress. Here, we cloned the Cu/ZnSOD (LdCZS) and MnSOD (LdMS) mRNA of Lymantria dispar by rapid amplification of cDNA ends (RACE). Afterwards their expression patterns were detected by quantitative real-time polymerase chain reaction (qPCR) after bioinformatic analysis.

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