We introduced a two-dimensional vector-bending sensor using excessively tilted fiber grating (ExTFG) encapsulated in a non-neutral axis position within a flexible cylinder. The asymmetrical structure enabled both TM and TE modes of the ExTFG to achieve the competency of one-dimensional vector bending sensing by cleverly leveraging the orthogonal relationship between these modes to achieve the effect of orthogonal cascading of two one-dimensional sensors. The resonance wavelength changes of the TM and TE modes were monitored under equal excitation states to achieve two-dimensional vector bending sensing, which significantly simplified the manufacturing complexity of the sensor; the longer the off-axis distance, the higher the sensitivity, and the smaller the maximum measurable curvature.
View Article and Find Full Text PDFToxicol Appl Pharmacol
November 2024
Front Cardiovasc Med
September 2024
Aims: This study aims to explore the different transition patterns and capture types during two bipolar pacing tests based on the selective left bundle branch (LBB) capture determined by the continuous pacing and recording technique.
Methods: In total, 67 patients completed two unipolar and two bipolar pacing tests based on selective LBB capture during screwing-in for left bundle branch pacing (LBBP) using the continuous pacing and recording technique. The electrophysiological characteristics and potential mechanisms of different pacing configurations were further evaluated in this study.
Solid bases are valuable catalysts for industrial syntheses. However, controlling the basicity of these catalysts remains a challenge. GaBO, due to μ-O within its structure, could behave as a special solid base catalyst exhibiting intrinsic Lewis basicity.
View Article and Find Full Text PDFSn-doped indium oxide (ITO) semiconductor nano-films are fabricated by plasma-enhanced atomic layer deposition using trimethylindium (TMIn), tetrakis(dimethylamino)tin (TDMASn), and Oplasma as the sources of In, Sn and O, respectively. A shared temperature window of 150 °C- 200 °C is observed for the deposition of ITO nano-films. The introduction of Sn into indium oxide is found to increase the concentration of oxygen into the ITO films and inhibit crystallization.
View Article and Find Full Text PDFACS Appl Mater Interfaces
June 2024
Rare-earth halide double perovskites (DPs) have attracted extensive attention due to their excellent optoelectronic performance. However, the correlation between luminescence performance, crystal structure, and temperature, as well as the inherent energy transfer mechanism, is not well understood. Herein, Lanthanide ions (Ln: Nd or Dy) as the co-dopants are incorporated into Sb doped CsNaYbCl DPs to construct energy transfer (ET) models to reveal the effects of temperature and energy levels of rare earth on luminescence and ET.
View Article and Find Full Text PDFBackground: Gemcitabine (GEM) resistance is the primary reason why combination chemotherapy is limited in triple-negative breast cancer (TNBC). Ganoderic acid D (GAD), a natural triterpenoid compound obtained from Ganoderma lucidum, has been shown to have antitumor activities. However, whether GAD can reverse GEM resistance in TNBC requires further investigation.
View Article and Find Full Text PDFThis work proposes a highly sensitive sandwich heterostructure multimode optical fiber microbend sensor for heart rate (HR), respiratory rate (RR), and ballistocardiography (BCG) monitoring, which is fabricated by combining a sandwich heterostructure multimode fiber Mach-Zehnder interferometer (SHMF-MZI) with a microbend deformer. The parameters of the SHMF-MZI sensor and the microbend deformer were analyzed and optimized in detail, and then the new encapsulated method of the wearable device was put forward. The proposed wearable sensor could greatly enhance the response to the HR signal.
View Article and Find Full Text PDFChiral hybrid metal halides hold great potential as circularly polarized luminescence light sources. Herein, we have obtained two enantiomeric pairs of one-dimensional hybrid chiral manganese(II) chloride single crystals, R/S-(3-methyl piperidine)MnCl (R/S-1) and R/S-(3-hydroxy piperidine)MnCl (R/S-2), crystallizing in the non-centrosymmetric space group P222. In comparison to R/S-1, R/S-2 single crystals not only show red emission with near-unity photoluminescence quantum yield (PLQY) and high resistance to thermal quenching but also exhibit circularly polarized luminescence with an asymmetry factor (g) of 2.
View Article and Find Full Text PDFAntipsychotic drug treatment for schizophrenia (SZ) can alter brain structure and function, but it is unclear if specific regional changes are associated with treatment outcome. Therefore, we examined the effects of antipsychotic drug treatment on regional grey matter (GM) density, white matter (WM) density, and functional connectivity (FC) as well as associations between regional changes and treatment efficacy. SZ patients (n = 163) and health controls (HCs) (n = 131) were examined by structural magnetic resonance imaging (sMRI) at baseline, and a subset of SZ patients (n = 77) were re-examined after 8 weeks of second-generation antipsychotic treatment to assess changes in regional GM and WM density.
View Article and Find Full Text PDFSheng Wu Gong Cheng Xue Bao
January 2024
The Spt-Ada-Gcn5-acetyltransferase (SAGA) is an ancillary transcription initiation complex which is highly conserved. The ADA1 (alteration/deficiency in activation 1, also called histone H2A functional interactor 1, HFI1) is a subunit in the core module of the SAGA protein complex. ADA1 plays an important role in plant growth and development as well as stress resistance.
View Article and Find Full Text PDFHerein, we successfully prepare conductive polyaniline (PANI)-encapsulated CsPbBr perovskite nanocrystals (PNCs) that demonstrate much improved photocatalytic performance and stability toward the CO reduction reaction (CRR) coupled with oxidation of benzyl alcohol (BA) to benzaldehyde. Due to the acid-base interaction between CO and PANI, CO molecules are selectively adsorbed on PANI in the form of carbamate. As a result, the rate of production of CO () reaches 26.
View Article and Find Full Text PDFThis study introduces a new wearable fiber-optic sensor glove. The glove utilizes a flexible material, polydimethylsiloxane (PDMS), and a silicone tube to encapsulate fiber Bragg gratings (FBGs). It is employed to enable the self-perception of hand posture, gesture recognition, and the prediction of grasping objects.
View Article and Find Full Text PDFPartitioning defective 3 (Par3) is a polarity protein critical in establishing epithelial cell polarity and tight junctions (TJs). Impaired intestinal epithelial barrier integrity is closely associated with colitis-associated colorectal cancer (CRC) progression. According to the GEO and TCGA database analyses, we first observed that the expression of Par3 was reduced in CRC patients.
View Article and Find Full Text PDFGlutamate receptor-like (GLR) is an important class of Ca channel proteins, playing important roles in plant growth and development as well as in response to biotic and abiotic stresses. In this paper, we performed genome-wide identification of banana gene family based on banana genomic data. Moreover, we analyzed the basic physicochemical properties, gene structure, conserved motifs, promoter -acting elements, evolutionary relationships, and used real-time fluorescence quantitative polymerase chain reaction (RT-qPCR) to verify the expression patterns of some family members under low temperature of 4 ℃ and different hormone treatments.
View Article and Find Full Text PDFAn environmental risk factor for schizophrenia (SZ) is maternal infection, which exerts longstanding effects on the neurodevelopment of offspring. Accumulating evidence suggests that synaptic disturbances may contribute to the pathology of the disease, but the underlying molecular mechanisms remain poorly understood. Erythropoietin-producing hepatocellular B (EphB) receptor signaling plays an important role in synaptic plasticity by regulating the formation and maturation of dendritic spines and regulating excitatory neurotransmission.
View Article and Find Full Text PDFA traditional fluorescence-scattering intensity based ratiometric sensing system utilizes both inherent scattering and fluorescence intensity and has drawn extensive attention owing to its simplicity and self-calibration properties. In this work, we propose a novel ratiometric fluorescence sensing system that combines a fluorescence wavelength shift and scattering in a single window, using second-order scattering (SOS) as the representative scattering signal based on the halide exchange of CsPbBr@SiO perovskite nanocrystal composites. We observe a fast halide exchange within 10 seconds, resulting in an identifiable fluorescence wavelength blue shift, while the scattering wavelength remains relatively constant for self-correction.
View Article and Find Full Text PDF() is a zoonotic parasite that is widely distributed and seriously endangers public health and human health. Therefore, accurate and effective detection of is crucial. This study proposes a microfluidic biosensor using a thin-core microfiber (TCMF) coated with molybdenum disulfide (MoS) for immune detection of .
View Article and Find Full Text PDFThe rapid and precise detection of chloride ions in biosystems is of great importance for clinical diagnosis. In this work, hydrophilic CsPbBr perovskite nanocrystals (PNCs) with a high photoluminescence (PL) quantum yield (QY) of 59% (0.5 g L) are successfully achieved through the passivation of micellar glycyrrhizic acid (GA), which enables good dispersion of PNCs in ethanol.
View Article and Find Full Text PDFBackground: Evidence from functional and structural research suggests that abnormal brain activity plays an important role in the pathophysiology of schizophrenia (SZ). However, limited studies have focused on post-treatment changes, and current conclusions are inconsistent.
Study Design: We recruited 104 SZ patients to have resting-state functional magnetic resonance imaging scans at baseline and 8 weeks of treatment with second-generation antipsychotics, along with baseline scanning of 86 healthy controls (HCs) for comparison purposes.
A label-free microfluidic immunosensor based on the double helix microfiber coupler (DHMC) coated with graphene oxide (GO) was proposed for the specific detection of anti-Müllerian hormone (AMH). Two single-mode optical fibers were twisted in a parallel direction, the coning machine was used to fuse and taper them, and the high-sensitivity DHMC was obtained. To make a stable sensing environment, it was immobilized in a microfluidic chip.
View Article and Find Full Text PDFCrystal growth from nanoscale constituents is a ubiquitous phenomenon in biology, geology and materials science. Numerous studies have focused on understanding the onset of nucleation and on producing high-quality crystals by empirically sampling constituents with different attributes and varying the growth conditions. However, the kinetics of post-nucleation growth processes, an important determinant of crystal morphology and properties, have remained underexplored due to experimental challenges associated with real-space imaging at the nanoscale.
View Article and Find Full Text PDFFerroelectric field effect transistor (FeFET) memories with hafnium zirconium oxide (HZO) ferroelectric gate dielectric and ultrathin InOchannel exhibit promising applicability in monolithic three-dimensional (M3D) integrated chips. However, the inferior stability of the devices severely limits their applications. In this work, we studied the effect of single cycle of atomic-layer-deposited Al-O bonds repeatedly embedded into an ultrathin InOchannel (∼2.
View Article and Find Full Text PDFThis study proposes a refractive index (RI) sensor using a cascaded tapered thin-core microfiber (TTCMF) based on the Vernier effect. The thin-core fiber was made into a TTCMF by arc discharging and flame heating and then sandwiched between two single-mode fibers (SMFs). The two structures with the same SMF-TTCMF-SMF but slightly different free spectral ranges (FSRs) were cascaded to generate the Vernier effect.
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