Hepatic cystic echinococcosis (type II): A case report.

This article presents a case report of a rare instance of hepatic cystic echinococcosis (Type II). The patient is a young female who has resided in the Inner Mongolia region of China for an extended period and has a clear history of contact with dogs and sheep. She presented with recurrent upper abdominal pain accompanied by jaundice of skin and sclera for 2 months.

Magnetar emergence in a peculiar gamma-ray burst from a compact star merger.

The central engine that powers gamma-ray bursts (GRBs), the most powerful explosions in the universe, is still not identified. Besides hyper-accreting black holes, rapidly spinning and highly magnetized neutron stars, known as millisecond magnetars, have been suggested to power both long and short GRBs. The presence of a magnetar engine following compact star mergers is of particular interest as it would provide essential constraints on the poorly understood equation of state for neutron stars.

Quantifying the distinct role of plasmon enhancement mechanisms in prototypical antenna-reactor photocatalysts.

Plasmonic photocatalysis enabled by the unique localized surface plasmon resonance represents a promising approach for efficient solar energy conversion. Elucidating the distinct plasmonic catalytic mechanisms and quantification of their effect is crucial yet highly challenging, due to their complex and synergistic nature. Herein, we achieve the differentiation and quantification of thermal as well as various non-thermal reaction mechanisms in prototypical Au-[Fe(bpy)] antenna-reactor photocatalysts using water splitting as test reaction.

[Effectiveness of digital three-dimensional printing osteotomy guide plate assisted total knee arthroplasty in treatment of knee osteoarthritis patients with femoral internal implant].

Objective: To investigate the effectiveness of digital three-dimensional (3D) printing osteotomy guide plate assisted total knee arthroplasty (TKA) in treatment of knee osteoarthritis (KOA) patients with femoral internal implants.

Methods: The clinical data of 55 KOA patients who met the selection criteria between July 2021 and October 2023 were retrospectively analyzed. Among them, 26 cases combined with femoral implants were treated with digital 3D printing osteotomy guide plate assisted TKA (guide plate group), and 29 cases were treated with conventional TKA (control group).

Two-step sequential energy transfer in sodium carboxymethyl cellulose-based gels for information encryption.

Sodium carboxymethyl cellulose (NaCMC)-based gels have been widely explored for various applications; however, innovative preparation methods are still required to further extend their potential. In this study, we introduced a low-molecular-weight gelator, 3,3',3″-[1,3,5-benzenetriyltris(carbonylimino)]trisbenzoic acid (HL), to induce gelation in NaCMC. The resulting NaCMC/HL gel was further developed into an information-encryption material with misleading functionality.

Efficacy and safety of PD-1/PD-L1 inhibitors in advanced or recurrent endometrial cancer: a meta-analysis with trial sequential analysis of randomized controlled trials.

Background: The combination of programmed cell death 1 (PD-1)/programmed death ligand 1 (PD-L1) inhibitors with chemotherapy (CT) is currently under evaluation as a first-line treatment for advanced or recurrent endometrial cancer (EC). This study sought to assess the efficacy and safety of this therapeutic combination in patients with advanced or recurrent EC.

Methods: We performed an exhaustive review of randomized controlled trials (RCTs) up to September 25, 2024, examining the efficacy and safety of combining PD-1/PD-L1 inhibitors with CT versus CT alone (or plus placebo) in advanced or recurrent EC.

Association between exposure to per- and polyfluoroalkyl substances (PFAS) and chronic cough in American adults: Results from NHANES 2003-2012.

Chronic cough, which affects approximately 10 % of the global population, is recognized as a significant health issue, especially among females. Recent research suggests that chronic cough may be an independent disease rather than merely a symptom of other conditions. This study focuses on the potential role of exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS) in the development of chronic cough, noting that PFAS exposure has been linked to various adverse health outcomes.

Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats.

Objectives: Atractylenolide III (ATL III) is the major bioactive component found in Atractylodes macrocephala, which has shown a range of benefits in pharmacological studies, including neuroprotection, anti-neuroinflammatory properties, antioxidant effects, anti-allergic effects, anti-cancer properties and antifibrotic abilities. Here, we investigated the therapeutic potential and underlying mechanisms of ATL III in the treatment of post-traumatic joint contracture (PTJC) in rat knees.

Methods: The rat PTJC model and TGF-β1-induced a primary synovial fibroblast model were used to observe several fibrotic markers (α-SMA、TGF-β1、FGF2、COL1A1and COL3A1) using histological staining, immunofluorescence and western blot.

Thermally activated fluorescence in 9,10-DPA single crystals enabling high-performance fast neutron detection.

Organic scintillators occupy a significant niche in the realm of fast neutron detection. Nevertheless, the cultivation of large-sized and high-quality organic single crystals has persistently posed a formidable challenge. 9,10-diphenylanthracene (DPA) was chosen as a prospective material for fast neutron detection.

Examining spatiotemporal dynamics of CO emission at multiscale based on nighttime light data.

Carbon emissions have increasingly been the focus of all governments as countries throughout the world choose carbon neutrality as a national development strategy. The analysis of the spatiotemporal dynamics of CO emission has emerged as a significant research topic considering the dual-carbon goal. In this research, we explore the spatiotemporal changes of CO emission at different scales based on nighttime light data.

Peptide platform for 3D-printed Ti implants with synergistic antibacterial and osteogenic functions to enhance osseointegration.

Bone defects caused by trauma, infection, or tumors present a major clinical challenge. Titanium (Ti) implants are widely used due to their excellent mechanical properties and biocompatibility; however, their high elastic modulus, low surface bioactivity, and susceptibility to infection hinder osseointegration and increase failure rates. There is an increasing demand for implants that can resist bacterial infection while promoting osseointegration.

Shell Dependence of Highly Tunable Circular Dichroism in Chiral Hybrid Plasmonic Nanomaterials for Chiroptical Applications.

Chiral plasmonic nanomaterials with fascinating physical and chemical properties show emerging chirality-dependent applications in photonics, catalysis, and sensing. The capability to precisely manipulate the plasmonic chirality in a broad spectral range plays a crucial role in enabling the applications of chiral nanomaterials in diverse and complex scenarios; however, it remains a challenge yet to be addressed. Here we demonstrate a strategy to significantly enhance the tunability of circular dichroism (CD) spectra of chiral nanomaterials by constructing core-shell hybrid metal-semiconductor structures with tailored shells.

Anisotropic Plasmon Resonance in TiCT MXene Enables Site-Selective Plasmonic Catalysis.

The ever-growing interest in MXenes has been driven by their distinct electrical, thermal, mechanical, and optical properties. In this context, further revealing their physicochemical attributes remains the key frontier of MXene materials. Herein, we report the anisotropic localized surface plasmon resonance (LSPR) features in TiCT MXene as well as site-selective photocatalysis enabled by the photophysical anisotropy.

Integrating bioinformatics and machine learning to unravel shared mechanisms and biomarkers in chronic obstructive pulmonary disease and type 2 diabetes.

Background: Chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are on the rise. While there is evidence of a link between the two diseases, the pathophysiological mechanisms they share are not fully understood.

Methods: In this study, the co-expressed genes of COPD and T2DM in Gene Expression Omnibus database were identified by bioinformatics method, and the functional enrichment analysis was performed.

Monitoring long-term cardiac activity with contactless radio frequency signals.

Cardiovascular diseases claim over 10 million lives annually, highlighting the critical need for long-term monitoring and early detection of cardiac abnormalities. Existing techniques like electrocardiograms (ECG) and Holter are accurate but suffer from discomfort caused by body-attached electrodes. While wearable devices using photoplethysmography offer more convenience, they sacrifice accuracy and are susceptible to environmental interference.

Mucosal Hub Bacteria as Potential Targets for Improving High-Fat Diet-Related Intestinal Barrier Injury.

Intestinal barrier injury contributes to multiple diseases such as obesity and diabetes, whereas no treatment options are available. Due to close interactions between mucosal microbiome and intestinal barrier, we evaluated the potential of mucosal bacteria in providing targets for high-fat diet (HFD)-related intestinal barrier injury. Whole-genome metagenomics was used to evaluate mucosal microbiome, while intestinal barrier injury was estimated using serum LPS, FITC-dextran intensity, and ZO-1 protein.

Characterization of a Putative Lysin from Enterococcus faecalis Phage IME-EFm1 and Determination of its Protective Efficacy in Mice.

The rising tide of bacterial drug resistance has sparked renewed interest in bacteriophages, the natural predators of bacteria. Our study highlights IME-EFm1, a Caudoviricetes bacteriophage specifically targeting Enterococcus faecium. Through our investigations, we identified that the gene IME-EFm1-ORF24 encodes an amidase, referred to as gp24, with promising lytic capabilities.

Sensitive and portable intelligent detection platform construction and dietary risk assessment of procymidone in Chinese leek, cowpea and celery.

Procymidone (PRM), a widely used amide-type fungicide in vegetables, poses potential health risks due to its high detection rate. This study introduces a pretreatment device and an intelligent quantification method for PRM in Chinese leek, cowpea, and celery using a lateral flow immunoassay (LFIA) integrated with a smartphone. The whole pretreatment and detection process can be achieved within 21 min.

Elucidating the influence of volatile compounds on aroma profiles across peach ( L.) cultivars and offspring exhibiting diverse flesh colors.

Yellow- and white-fleshed peach fruits are favored for their diverse flesh colors. While carotenoid accumulation primarily dictates flesh color differences, the influence of volatile compounds on their aromas remains largely unexplored. Here, multiple analytical methods including odor importance assessment, hierarchical clustering, and aroma characterization analysis were employed to investigate volatile compositions and aroma characteristics of the two types of peach, as well as the offspring with identical parentage.

Mormyroidea-inspired electronic skin for active non-contact three-dimensional tracking and sensing.

The capacity to discern and locate positions in three-dimensional space is crucial for human-machine interfaces and robotic perception. However, current soft electronics can only obtain two-dimensional spatial locations through physical contact. In this study, we report a non-contact position targeting concept enabled by transparent and thin soft electronic skin (E-skin) with three-dimensional sensing capabilities.

Rapid Dual-Gene Detection of Burkholderia gladioli and Subspecies Cocovenenans in Fresh Noodles and Tremella Using CRISPR-Cas12a/Cas13a.

Background: Burkholderia gladioli pv. cocovenenans is a notable foodborne pathogen that poses a significant risk to food safety. Contaminated food requires distinct classification and treatment procedures for non-pathogenic B.

Analysis of risk factors for carotid artery plaque in asymptomatic adults.

Objective: This study aimed to investigate the risk factors affecting the presence of carotid plaque in asymptomatic adults.

Methods: Asymptomatic adults (age > 40 years, no symptoms of cardiovascular and cerebrovascular diseases) undergoing routine health examinations from physical examination department were included in this study. Carotid plaque was measured by Resona 7OB and Resona 8EXP color Doppler ultrasound and L9-3U and L4-5WU probes.

Application of target scanning combined with three-dimensional reconstruction in the diagnosis of early-stage lung adenocarcinoma.

This study aimed to assess the diagnostic value of target scanning combined with three-dimensional reconstruction in early-stage lung adenocarcinoma. A retrospective analysis was conducted on 2017 patients with pathologically confirmed early-stage lung adenocarcinoma who underwent thoracoscopic lobectomy at the First Affiliated Hospital of Anhui Medical University from September 2018 to May 2023. These patients were initially diagnosed using conventional spiral CT scanning, and the study explored the application of target scanning combined with three-dimensional reconstruction in the diagnosis of early-stage lung adenocarcinoma.