Publications by authors named "Bin-Yun Liu"
[Detection and Significance of Molecular Markers in Immunotherapy and Targeted Therapy of Colorectal Cancer in Tibet].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2024
Article Synopsis
- The study aimed to analyze the expression of several genes and proteins related to colorectal cancer in Tibetan patients, specifically SMARCA4, BRAF, P53, PD-1, and PD-L1, to inform targeted and immunotherapy options.
- Researchers included 64 colorectal cancer patients from a local hospital, investigating tumor characteristics like location, type, and gene mutations using techniques such as immunohistochemistry and PCR.
- Results showed a predominance of adenocarcinomas, with the majority of patients in advanced cancer stages, revealing varied expression levels of key proteins and a notable presence of P53 mutations, while no gene fusions involving NTRK were found.