Publications by authors named "Bin-Sen Huang"
Diagnostic and prognostic value of serum L1-cell adhesion molecule in esophageal squamous cell carcinoma.
Clin Res Hepatol Gastroenterol
December 2018
Article Synopsis
- - The study aimed to investigate serum levels of L1 cell adhesion molecule (L1CAM) in patients with esophageal squamous cell carcinoma (ESCC) and found significantly lower levels in ESCC patients compared to normal controls.
- - Serological testing for L1CAM showed low sensitivity (28.3%) but high specificity (90.4%) for diagnosing ESCC, indicating it may not be a highly effective screening tool, particularly for early-stage cancer.
- - Lower levels of serum L1CAM were associated with deeper tumor invasion and significantly correlated with shorter overall and disease-free survival times in ESCC patients, suggesting it could be a useful biomarker for prognosis.