Association of BCL-2 polymorphism with the presence and severity of lumbar disc degeneration in the Chinese Han population.

Background: Apoptosis is involved in the mechanism of lumbar disc disease (LDD). BCL-2 has been shown to play an anti-apoptosis role. The present study aims to examine the association of -938C > A polymorphism of the BCL-2 gene with the presence and severity of LDD in the Chinese Han population.