Comparative Transcriptome Analysis Highlights the Role of in the Honeydew Production of Virulent Brown Planthoppers ( Stål) to Resistant Rice Variety.

Brown planthoppers (BPHs, Stål) are a major threat to rice cultivation in Asia, necessitating the development of pest-resistant varieties for effective management. However, the adaptability of BPHs has resulted in the development of virulent populations, such as biotype Y BPHs, which exhibit significant virulence against the rice variety YHY15 that harbors the resistance gene . The various response mechanisms of BPH populations to resistant rice varieties are critical yet underexplored.

Oxidized hyaluronic acid/ε-polylysine/quaternized chitosan hydrogel with shear thinning injectability and self-healing properties for full-time and multipurpose wound healing.

Complex wound closure scenarios necessitate the development of advanced wound dressings that can effectively address the challenges of filling irregularly shaped wounds and managing fatigue failures encountered in daily patient activities. To tackle these issues, we develop a multifunctional hydrogel from natural polysaccharides and polypeptides with injectability and self-healing properties for promoting full-time and multipurpose wound healing. Synthesized through dynamic Schiff base linkages between oxidized hyaluronic acid (OHA), ε-polylysine (ε-PL), and quaternized chitosan (QCS), the OHA/ε-PL/QCS hydrogel can gel rapidly within 50 s.

LIPUS activated piezoelectric pPLLA/SrSiO composite scaffold promotes osteochondral regeneration through P2RX1 mediated Ca signaling pathway.

Addressing the concurrent repair of cartilage and subchondral bone presents a significant challenge yet is crucial for the effective treatment of severe joint injuries. This study introduces a novel biodegradable composite scaffold, integrating piezoelectric poly-l-lactic acid (pPLLA) with strontium-enriched silicate bioceramic (SrSiO). This innovative scaffold continually releases bioactive Sr and SiO ions while generating an electrical charge under low-intensity pulsed ultrasound (LIPUS) stimulation, a clinically recognized method.

Global stability boundary analysis and verification of aviation pressure servo-controlled actuator system.

In this paper, the mathematical model of the aviation pressure servo valve controlled actuator system(APSVCAS) considering nonlinearity is established based on a jet pipe pressure servo valve in this article. And the dynamic characteristics and stability boundary of APSVCAS are analyzed, which provides theoretical guidance for the actual composition and the determination of parameters. Firstly, a jet-tube two-stage pressure servo valve for aviation hydraulic system is designed, and an accurate model of APSVCAS is established considering multiple nonlinear factors.

Periodic mesoporous organosilica-loaded mincle agonists enhance the immunogenicity of COVID-19 subunit vaccines by dual activation of B cells and dendritic cells.

Effective vaccination is crucial for intervening in the COVID-19 pandemic. However, with the continuous mutation of the SARS-CoV-2, existing vaccines including subunit vaccines cannot effectively prevent virus infections. Hence, there is an urgent need to enhance the immunogenicity of existing vaccines to induce a more potent and durable immune response.

Neurotransmitter-Mimicking Nanovesicles Facilitate Postoperative Glioblastoma Stem Cell-Specific Treatment for Preventing Tumor Recurrence.

Survival quality of glioblastoma (GBM) patients remains undesirable despite the aggressive multimodal treatment methods implemented, which are strongly associated with tumor recurrence after surgical resection. Self-renewal and strong tumourigenic capacity of glioblastoma stem cells (GSCs) at the narrow margin of the incision are essential factors driving tumor secondary strikes. Currently, the challenges in treating postoperative residual GSCs are mainly due to the lack of materials for incision and GSCs targeting.

Unveiling relationships of human instinctive behaviors and blood pressure in Chinese adults: A network analysis.

Objectives: Human behaviors and blood pressure (BP) are closely intertwined, affecting health. However, few studies have demonstrated their complex relationships. Using network analysis, we aimed to untangle the intricate and potential causal relationships between BP and human instinctive behaviors, identifying potential action points for hypertension prevention and control.

Effectiveness of high-intensity inspiratory muscle training, and resistance and aerobic exercise for cardiovascular health in chronic obstructive pulmonary disease (HIRAC-COPD): a randomized controlled trial protocol.

Background: Cardiovascular diseases are among the most common and clinically significant comorbidities of chronic obstructive pulmonary disease (COPD). Exercise has been shown to reduce the risk of cardiovascular diseases, and high-intensity inspiratory muscle training (H-IMT) has emerged as a promising intervention for improving arterial stiffness in individuals with COPD. Yet, there is limited evidence from randomized controlled trials (RCTs) regarding the impact of H-IMT alone or in combination with exercise on reducing arterial stiffness in COPD.

Hydrogels of dialdehyde starch and gelatin cross-linked with potential application as tissue adhesives.

Invasive surgical methods are the current standard for hemostasis and wound closure. In recent years, injectable hydrogels prepared from natural biomacromolecules have shown promise as tissue adhesives to overcome their shortcomings due to their high hydrophilicity and biocompatibility, but the inherent properties of unmodified biomolecules remain a major challenge in their application. In this paper, a hydrogel (DS/Gel-CDH) with self-healing, injectable and adhesive functions was constructed by Schiff base crosslinking between carbonyl hydrazide modified gelatin (Gel-CDH) and dialdehyde starch (DS).

A novel ATP-binding cassette protein (NoboABCG1.3) plays a role in the proliferation of Nosema bombycis.

ATP-binding cassette (ABC) transporter proteins, one of the largest families of membrane transport proteins, participate in almost all biological processes and widely exist in living organisms. Microsporidia are intracellular parasites; they can reduce crop yields and pose a threat to human health. The ABC proteins are also present in microsporidia and play a critical role in their proliferation and energy transport.

A Temporal Network Based on Characterizing and Extracting Time Series in Copper Smelting for Predicting Matte Grade.

Addressing the issues of low prediction accuracy and poor interpretability in traditional matte grade prediction models, which rely on pre-smelting input and assay data for regression, we incorporate process sensors' data and propose a temporal network based on Time to Vector (Time2Vec) and temporal convolutional network combined with temporal multi-head attention (TCN-TMHA) to tackle the weak temporal characteristics and uncertain periodic information in the copper smelting process. Firstly, we employed the maximum information coefficient (MIC) criterion to select temporal process sensors' data strongly correlated with matte grade. Secondly, we used a Time2Vec module to extract periodic information from the copper smelting process variables, incorporates time series processing directly into the prediction model.

Synthesis and Structural Modulation of Nanoporous Copper Films by Magnetron Sputtering and One-Step Dealloying.

Nanoporous copper (np-Cu) has attracted much more attention due to its lower cost compared to other noble metals and high functionality in practical use. Herein, AlCu(x = 13-88 at.%) precursor films with thicknesses of 0.

Fractionating the Flavonoids in Flos and via Solvent Extraction Coupled with Automated Solid-Phase Extraction.

Due to the structural diversity of flavonoids in functional plant foods and the inherent limitations of existing techniques, it is important to develop a simple and green (environmentally friendly) method of extracting flavonoids from plant foods. In this study, a method involving solvent extraction followed by automated solid-phase extraction was developed for extracting flavonoids from flos (JYH) and (SYH), both of which are widely used functional plant-based foods in Asian countries. For the optimisation of the solvent extraction method, solvent concentration (0.

Biomimetic Nanostructured Polyimine Aerogels with Graded Porosity, Flame Resistance, Intrinsic Superhydrophobicity, and Closed-Loop Recovery.

Polymer aerogels, with their porous and lightweight features, excel in applications such as energy storage, absorption, and thermal insulation, making them a sought-after new material. However, the covalent cross-linking networks of current polymer aerogels result in unsustainable manufacturing and processing practices, persistently depleting our finite natural resources and causing significant global environmental impacts. Herein, we have constructed a high-performance dynamic covalent cross-linking aerogel network using biobased materials, with its structure and green sustainability akin to those of plants in nature.

Synergistic interactions between gut microbiota and short chain fatty acids: Pioneering therapeutic frontiers in chronic disease management.

Microorganisms in the gut play a pivotal role in human health, influencing various pathophysiological processes. Certain microorganisms are particularly essential for maintaining intestinal homeostasis, reducing inflammation, supporting nervous system function, and regulating metabolic processes. Short-chain fatty acids (SCFAs) are a subset of fatty acids produced by the gut microbiota (GM) during the fermentation of indigestible polysaccharides.

Clinical Characteristics and Prognostic Factors of Patients with Intraocular Foreign Bodies from a Tertiary Eye Center in North China.

Background: This study aims to describe the epidemiology and clinical features of patients with intraocular foreign bodies (IOFBs) and analyze the prognostic factors influencing final vision.

Methods: We retrospectively reviewed medical records of patients with IOFBs admitted to Qingdao Eye Hospital of Shandong First Medical University between January 1, 2014, and December 31, 2021. Inclusion criteria involved complete clinical data details of patients diagnosed with intraocular foreign bodies in our hospital who were treated with concurrent surgery and based on IOFB position and characteristics, different surgical methods were employed.

Association between maternal exercise during pregnancy and attention-deficit/hyperactivity disorder among preschool children in Southwest China.

Objective: Maternal moderate-intensity exercise during pregnancy has important health benefits for the offspring, however, less is known about its association with offspring attention-deficit/hyperactivity disorder (ADHD). This study aimed to explore the association between maternal exercise during pregnancy and ADHD among preschool children in Southwest China.

Methods: A web-based cross-sectional study was performed in 2021, and the revised Conners Parental Symptom Questionnaire and maternal exercise during pregnancy were obtained through a self-reported structured questionnaire.

Tm-Based Downshifting Nanoprobes with Enhanced Luminescence at 1680 nm for In Vivo Vascular Growth Monitoring.

Optical imaging in the 1500-1700 nm region, known as near-infrared IIb (NIR-IIb), shows potential for noninvasive in vivo detection owing to its ultrahigh tissue penetration depth and spatiotemporal resolution. Rare earth-doped nanoparticles have emerged as widely used NIR-IIb probes because of their excellent optical properties. However, their downshifting emissions rarely exhibit sufficient brightness beyond 1600 nm.

Loneliness is associated with diminished heart rate variability reactivity to acute social stress in younger adults.

Loneliness is linked to cardiovascular health, with atypical stress reactivity serving as an underlying mediator. This study aimed to investigate the association between loneliness and heart rate variability (HRV) reactivity to acute social stress in younger adults. A total of 92 participants (52 women; mean age = 22.

, and serve as potential molecular biomarkers for sepsis based on bioinformatics analysis.

Purpose: Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection, and it probably represents a pattern of response by the immune system to injury. However, the relationship between biomarkers and sepsis remains unclear. This study aimed to find potential molecular biomarkers, which could do some help to patients with sepsis.

The host restriction factor SERINC5 inhibits HIV-1 transcription by negatively regulating NF-κB signaling.

Serine incorporator 5 (SER5) can be incorporated into HIV-1 virions to block viral entry by disrupting the envelope glycoprotein-mediated viral fusion to the plasma membrane. Recent studies suggest that SER5 also inhibits HIV-1 mRNA transcription and the subsequent progeny virion biogenesis. However, the underlying mechanisms through which SER5 antagonizes the viral transcription remain poorly understood.

Metaplasticity-Enabled Graphene Quantum Dot Devices for Mitigating Catastrophic Forgetting in Artificial Neural Networks.

The limitations of deep neural networks in continuous learning stem from oversimplifying the complexities of biological neural circuits, often neglecting the dynamic balance between memory stability and learning plasticity. In this study, artificial synaptic devices enhanced with graphene quantum dots (GQDs) that exhibit metaplasticity is introduced, a higher-order form of synaptic plasticity that facilitates the dynamic regulation of memory and learning processes similar to those observed in biological systems. The GQDs-assisted devices utilize interface-mediated modifications in asymmetric conductive pathways, replicating classical synaptic plasticity mechanisms.

Dual-Functionalized Injectable pH-Responsive Hydrogels Loaded with Magnesium Peroxide for the Treatment of Implant-Associated Infection.

Implant-associated infections frequently complicate orthopedic surgeries, resulting in challenging issues. The current therapy of antibiotic treatment and surgical debridement often leads to drug resistance and bone defect. The development of pH-responsive antimicrobial and pro-osteogenic materials is a promising approach to controlling infections and repairing infected bone defects, especially given the weakly acidic pH of the bacterial infection area.