Design and Experiment of a PLC-Based Intelligent Thermal Insulation Box for Nursing Piglets.

Local heating of the activity area for nursing piglets is crucial for piglet health and the energy efficiency of barn climate control. Traditional heating methods using lamps or covers lack precise control, result in significant energy waste, and cannot be dynamically adjusted according to piglet age or changing environmental temperatures. To address these issues, this study designed a Programmable Logic Controller (PLC)-based thermal insulation box for nursing piglets, utilizing a strip heater instead of the conventional round heating lamp.

Cyclometalated ruthenium (II) complex-based nanoparticles for enhanced microRNAs detection and imaging in living cells.

MicroRNA (miRNA) imaging in living cells is paramount for comprehending its dynamic functions and profiles, offering valuable insights into miRNA-related cellular processes. However, this remains challenging due to limited transfection agents and the low abundance of miRNAs. Herein, a smart nanosystem was proposed for miRNA imaging in living cells by ingeniously integrating cyclometalated ruthenium (II) nanoparticles (RuNPs) with a catalyzed hairpin assembly (CHA) strategy.

The mediating effects of gestational diabetes mellitus and hypertensive disorders of pregnancy between maternal advanced age, previous caesarean section and the risk of small- or large-for-gestational-age newborns: a multicentric prospective cohort study in southern China.

Background: Maternal obstetric characteristics have a key role in determining the occurrence of pregnancy-related disorders and subsequent neonatal outcomes. We aimed to investigate the mediating impact of gestational diabetes mellitus (GDM) and hypertensive disorder of pregnancy (HDP) on the relationship between maternal advanced age, previous caesarean section, and the risk of either large for gestational age (LGA) or small for gestational age (SGA) infants.

Methods: We used data from a prospective multicentre cohort study conducted through China's National Maternal Near-miss Surveillance System from January 2012 to December 2021.

A Three-Dimensional, Flexible Conductive Network Based on an MXene/Rubber Composite for Lithium Metal Anodes.

Flexibility enhancement is a pressing issue in the current development of advanced lithium-metal battery applications. Many types of organic polymers are inherently flexible, which can form a composite structure enhancing electrode flexibility. However, organic polymers have a negative influence on the plating and stripping of lithium-metal anodes, and the large number of polymers block the pore of the material, reducing the utilization of the active site.

HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis.

Advanced atherosclerosis is the pathological basis for acute cardiovascular events, with significant residual risk of recurrent clinical events despite contemporary treatment. The death of foamy macrophages is a main contributor to plaque progression, but the underlying mechanisms remain unclear. Bulk and single-cell RNA sequencing demonstrated that massive iron accumulation in advanced atherosclerosis promoted foamy macrophage ferroptosis, particularly in low expression of triggering receptor expressed on myeloid cells 2 (TREM2) foamy macrophages.

Characteristics of peripheral immune response induced by large-vessel occlusion in patients with acute ischemic stroke.

Introduction: Despite improvements in the treatment of acute ischemic stroke (AIS), some patients still suffer from functional impairments, indicating the poor understanding of pathophysiologic process of AIS. Inflammation plays an important role in the pathophysiology of AIS. The purpose of the study was to investigate the peripheral inflammation in different subtypes of AIS.

Molecular mechanisms of GSK3β-driven modulation of ABLIM1 and titin interactions in cardiac muscle.

The heart adapts to cardiac demand through a variety of mechanisms. Some of these adaptations include chemical modifications of myofilament proteins responsible for cell contraction. Interestingly, many of these chemical modifications, such as phosphorylation, are found in unstructured, or intrinsically disordered, regions of proteins.

Skin-Friendly Large Matrix Iontronic Sensing Meta-Fabric for Spasticity Visualization and Rehabilitation Training via Piezo-Ionic Dynamics.

Rehabilitation training is believed to be an effectual strategy that can reduce the risk of dysfunction caused by spasticity. However, achieving visualization rehabilitation training for patients remains clinically challenging. Herein, we propose visual rehabilitation training system including iontronic meta-fabrics with skin-friendly and large matrix features, as well as high-resolution image modules for distribution of human muscle tension.

Delta corticomedullary apparent diffusion coefficient on MRI as a biomarker for prognosis in IgA nephropathy.

Objectives: To explore the association of the cortico-medullary difference in apparent diffusion coefficient (ΔADC) with clinicopathological parameters of disease activity at the time of biopsy, and with the prognositic risk stratification in IgA nephropathy (IgAN) patients.

Methods: We included 112 patients with biopsy-proven IgAN who measured ΔADC. Patients underwent a kidney biopsy and diffusion-weighted magnetic resonance imaging within one week of the biopsy.

1+1<2: Combined effect of low temperature stress and salt stress on Sesuvium portulacastrum L.

To expedite the deployment of Sesuvium portulacastrum floating bed technology in Hangzhou Bay and the Yangtze River Estuary, and to overcome the cryogenic constraint, our study concentrated on investigating the impacts of both individual and combined stress factors, particularly low temperature and salinity, on its application. We detected the S. portulacastrum related enzyme activity and other biological macromolecules under low temperature stress, salt stress and combined stress.

Experimental study on the motion characteristics and critical hydraulic parameters of microplastics in a freshwater environment.

The migration behavior of microplastics in water is affected by many factors; in particular, the migration mechanism of microplastics in the terrestrial freshwater environment is more complicated than that in the marine environment. In order to understand the migration behavior of microplastics in the freshwater environment, the hydraulic parameter thresholds of different types of microplastics in water were identified based on hydraulic experiments and force analysis methods. The results show that the motion state of microplastics is affected by their own internal factors and external environmental factors, and the flow rate is the key external factor affecting the change of their motion state.

Flowable Oxygen-Release Hydrogel Inhibits Bacteria and Treats Periodontitis.

Periodontitis, the chronic inflammation of the periodontal tissues caused by bacteria in plaque, is the leading cause of tooth loss in adults in the world. Currently, periodontitis is effectively treated with mechanical cleaning and the use of antibiotics. However, these treatments only temporarily remove plaque, which can rapidly proliferate and multiply in periodontal pockets over time.

Rapid detection of carbapenemase production in using phenotypic tests based on colorimetric microtube assay.

Antibiotic resistance, particularly carbapenem resistance, poses a significant global health threat due to the limited availability of effective antibiotics. Carbapenem-resistant are increasingly recognized for their role in various infections, necessitating rapid and accurate detection methods. This study aimed to evaluate several phenotypic tests, including the Carba NP test (CNPt), Carba NP-direct test (CNPd), and Blue-Carba test (BCT), for their effectiveness in rapidly detecting carbapenemase production in .

Patterns of trace elements deposition in Indo-Pacific humpback dolphin (Sousa chinensis) teeth reflect early life history: A pilot study.

Understanding early life history events within a population is imperative for developing effective conservation and management practices, particularly for vulnerable species in degraded environments with high environmental variability. Here, we first investigated the lifetime record of trace element (TE) accumulation in the teeth of Indo-Pacific humpback dolphins from the Pearl River Estuary, China, using in-situ laser ablation-inductively coupled plasma-mass spectrometry microanalysis, and further explored the suitability of teeth TEs as bioindicators of critical life stages. A total of 26 TEs were detected in the teeth of eight dolphins, with concentrations ranging from 0.

The compact beam energy measurement method of the photocathode RF gun by the solenoid and beam shaping.

Beam energy, normalized emittance, and quantum efficiency are crucial parameters of the RF gun. In this study, we proposed a compact and low-cost method to measure the beam energy at the exit of the 120 MeV electron linac's RF gun. We utilized a solenoid magnetic field to rotate an elliptical beam and measured the rotation angle of the beam to calculate the energy.

[Retracted] MicroRNA‑195‑5p inhibits the progression of hemangioma via targeting SKI.

[This retracts the article DOI: 10.3892/etm.2021.

Precursor engineering towards orange- and red-emissive carbon dots for LEDs with tunable emission colors.

Carbon dots (CDs) have attracted significant research interest due to their great potential in optoelectronic applications. Although various CDs have been synthesized the "bottom-up" pathway, few studies have focused on understanding the origins of the structural and optical diversities of CDs. In this study, two benzenoid acids with a slight structural variation (, 9-oxo-9-fluorene-2,7-dicarboxylic acid (FR) and 4,4'-biphenyl dicarboxylic acid (BP)) are employed as precursors, yielding orange- and red-emissive CDs with quantum yields of 43.

An immortalized adipose-derived stem cells line from the -related overgrowth spectrum: Unveiling novel therapeutic targets.

PIK3CA-related overgrowth spectrum (PROS) encompasses several rare conditions that lead to overgrowth of various body parts resulting from activating variants in . The absence of ideal cell models significantly impedes progress in PROS research. In this study, we focused on facial infiltrating lipomatosis (FIL) (A disorder within PROS) and aimed to establish and characterize an immortalized PROS cell line.

Divergent Activity Shifts of Tin-Based Catalysts for Electrochemical CO Reduction: pH-Dependent Behavior of Single-Atom Versus Polyatomic Structures.

Tin (Sn)-based catalysts have been widely studied for electrochemical CO reduction reaction (CORR) to produce formic acid, but the intricate influence of the structural sensitivity in single-atom Sn (e.g., Sn-N-C) and polyatomic Sn (e.

Multifunctional nanocomposites utilizing ruthenium (II) complex/manganese (IV) dioxide nanoparticle for synergistic reinforcing radioimmunotherapy.

Radiotherapy (RT) stands as a frontline treatment modality in clinical breast oncology, yet challenges like ROS reduction, high toxicity, non-selectivity, and hypoxia hinder efficacy. Additionally, RT administered at different doses can induce varying degrees of radioimmunotherapy. High doses of radiation (>10 Gy) may result in immune suppression, while moderate doses (4-10 Gy), although capable of mitigating the immune suppression caused by high-dose radiation, are often insufficient in effectively killing tumor cells.

Harnessing biosynthesized selenium nanoparticles for recruitment of beneficial soil microbes to plant roots.

Root exudates can benefit plant growth and health by reshaping the rhizosphere microbiome. Whether nanoparticles biosynthesized by rhizosphere microbes play a similar role in plant microbiome manipulation remains enigmatic. Herein, we collect elemental selenium nanoparticles (SeNPs) from selenobacteria associated with maize roots.