Publications by authors named "Bin Bin He"

Background: Type 2 diabetes mellitus (T2DM) is a public health crisis that requires adequate knowledge, attitudes, and practices (KAP) by health care providers to prevent or delay the progression of the disease. This study aimed to assess the KAP regarding T2DM among primary care providers (PCPs) in Central China.

Methods: This multicenter cross-sectional study was conducted among 971 PCPs using self-employed KAP questionnaires.

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This paper handles with the Hadamard and the Caputo-Hadamard fractional derivative and stability of related systems without and with delay. Firstly, the derivative inequalities are obtained, which is indispensable in applying the theorems derived in this paper. Then, for systems without delay, we get the stability results by using the Lyapunov direct method and for systems with delay, we explore two useful inequalities to verify the stability.

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This article aims to assess the bioequivalence of the test and the reference metformin hydrochloride tablets in healthy Chinese volunteers under fasting and fed conditions and to explore the effect of food on the pharmacokinetic (PK) profiles of both formulations. In total, 56 healthy Chinese subjects (28 in each group) were enrolled in this randomized, open, single-center, single-dose, 2-treatment, 2-sequence, 2-cycle cross clinical trial. The subjects were administrated a single dose of the test and the reference tablets at 0.

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Aims: To evaluate the potential association of anemia with micro- and macrovascular complications in Chinese patient with type 2 diabetes mellitus (T2DM).

Methods: A total of 1997 patients with T2DM were included in this cross-sectional study. Patients were defined as anemic, if hemoglobin (Hb) levels were < 13 g/dL in males and < 12 g/dL in females.

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On the basis of analyzing the deficiency of spectral angle mapper (SAM), an improved similarity measure called weight SAM (WSAM) is proposed in the present paper. The fundamental idea is to set a weight in the "difference range" to increase the discriminability between the similar minerals. When we distinguish some kind of mineral, the authors can find the "difference range", in which the difference in spectral feature between the similar mineral spectrum and the reference spectrum is huge, and gives weight k to the spectrum in this range to reduce the similarity and increase the discriminability between similar minerals.

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Objective: To explore the therapeutic effects of amiodarone and metoprolol, either alone or in combination, on chronic heart failure (CHF) complicated by ventricular arrhythmia.

Methods: A total of 110 NYHA class II-III patients with CHF complicated by ventricular arrhythmia were randomly divided into amiodarone group, metoprolol group and amiodarone + metoprolol group. The therapeutic effects was evaluated at the end of the 1-year follow-up.

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Objective: To develop a novel gene delivery vector with poly-aspartamide-glutamic acid and polyethylenimine as the backbone.

Methods: alpha, beta-poly-(N-2-hydroxypropyl)-D, L-aspartamide-glutamic acid (PHPAG) was synthesized and low molecular weight polyethylenimine (PEI 1.8 kDa) was grafted to form PHPAG-PEI 1800.

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