[Kurloff's thymic inclusion : action on rat gonads in culture].

Thymic and splenic extracts rich in FOA-KURLOFF (F.K.) body cells, obtained from guinea-pigs treated with oestrogen, were added to rat testis or ovaries in culture.

[Neoplasm-resistance of guinea pigs: demonstration of a principle ensuring destruction of human cancer cells in culture].

The thymus and the spleen of guinea Pigs treated with oestrogen were rich in cells showing a special inclusion, the Foa-Kurloff body cell (F.K.).

[Action of thymic extracts on the growth of different cell populations in vitro].

Thymic, splenic and renal cellular extracts were obtained by tissular grinding and ultra centrifugation, from animals having undergone diverse hormonal treatments. These extracts were added to different cellular populations in culture (carcinomatous HeLa strain, established MRCs strain, primo-culture of human foetal lung strain). The thymic extracts of non treated animals and the splenic extracts rich in FK substance from intact guinea pigs treated by oestrogenes or FSH, provoque an inhibition of tumoral cell growth.

[Thymic Kurloff inclusion. Action on the ovogenesis of the rat].

Grafts and injections of cellular extracts from thymus and spleen of guinea pigs, were carried out in puberal and impuberal female rats. These organs are especially rich in Foa-Kurloff cells after oestrogentherapy. Kidney served as a reference material for the same experimental conditions.

[Interstitial plasma cells of the submaxillary glands].

Interstitial plasma cells are constantly present in the submaxillary gland. Their number varies greatly with species. They are normal cells, lymphocytes are never associated with them.

[Influence of genital hormones on guinea pig thymus gland cytology].

The changes of the thymic cytologia under the action of genital hormones were studied in giunea pigs. The conclusion of the experiments was: the oestrogens are the only hormones to induce a fast and complete involution of the thymic tissue with appearance of Foa-Kurloff cells'. The cell seems to have all the necessary characters to be the morphologic substratum of an eventual cytocrine secretion of the thymus.