Intraosseous Shelf Plate Fixation for Depressed Articular Fragments in Tibial Plateau Fractures: A Technical Trick and Case Series.

Tibial plateau fractures with severely displaced articular injuries and significant deformity to the surrounding metaphyseal bone (including the hyperextension varus bicondylar pattern) can be challenging to stabilize due to resulting large bone voids uncontained by metaphyseal cortex. The purpose of this report was to describe a technique to support the plateau articular surface in these cases and report on outcomes of a small series. This technique uses a small or mini fragment plate, contoured to function as an intraosseous shelf plate, with the "shelf" portion inserted into the bone beneath the articular surface to support it.

Dorsal Hook Plating of Patella Fractures With Immediate Range of Motion Results in Reliable Fixation, Low Implant Removal Rates, and Satisfactory Clinical Outcomes.

Objectives: To evaluate radiographic and clinical patient-reported outcomes following dorsal hook plating of displaced patella fractures with permittance of immediate postoperative active closed chain range of motion.

Design: Retrospective review of prospectively collected data.

Setting: Urban academic level 1 trauma center.

Clinical mutations in prime pathogen expansion under nutrient stress.

Persistent infection by has been linked to the bacterial stringent response (SR), a conserved stress response pathway regulated by the Rel protein. Rel synthesizes (p)ppGpp "alarmones" in response to amino acid starvation, which enables adaptation to stress by modulating bacterial growth and virulence. We previously identified five novel protein-altering mutations in that arose in patients with persistent methicillin-resistant bacteremia.

Wearable Nanocomposite Sensor System for Motion Phenotyping Chronic Low Back Pain: A BACPAC Technology Research Site.

Chronic low back pain (cLBP) is a prevalent and multifactorial ailment. No single treatment has been shown to dramatically improve outcomes for all cLBP patients, and current techniques of linking a patient with their most effective treatment lack validation. It has long been recognized that spinal pathology alters motion.

Hydrogen migration in inner-shell ionized halogenated cyclic hydrocarbons.

We have studied the fragmentation of the brominated cyclic hydrocarbons bromocyclo-propane, bromocyclo-butane, and bromocyclo-pentane upon Br(3d) and C(1s) inner-shell ionization using coincidence ion momentum imaging. We observe a substantial yield of CH fragments, whose formation requires intramolecular hydrogen (or proton) migration, that increases with molecular size, which contrasts with prior observations of hydrogen migration in linear hydrocarbon molecules. Furthermore, by inspecting the fragment ion momentum correlations of three-body fragmentation channels, we conclude that CH fragments (with x = 0, …, 3) with an increasing number of hydrogens are more likely to be produced via sequential fragmentation pathways.

Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk.

The tumor microenvironment plays a crucial role in both the development and progression of prostate cancer. Furthermore, identifying protein and gene expression differences between different regions is valuable for treatment development. We applied Digital Spatial Profiling multiplex analysis to formalin-fixed paraffin embedded prostatectomy tissue blocks to investigate protein and transcriptome differences between tumor, tumor-adjacent stroma (TAS), CD45+ tumor, and CD45+ TAS tissue.

Differentiating and Quantifying Gas-Phase Conformational Isomers Using Coulomb Explosion Imaging.

Conformational isomerism plays a crucial role in defining the physical and chemical properties and biological activity of molecules ranging from simple organic compounds to complex biopolymers. However, it is often a significant challenge to differentiate and separate these isomers experimentally as they can easily interconvert due to their low rotational energy barrier. Here, we use the momentum correlation of fragment ions produced after inner-shell photoionization to distinguish conformational isomers of 1,2-dibromoethane (CHBr).

Sustainable manufacturing of sensors onto soft systems using self-coagulating conductive Pickering emulsions.

Compliant sensors based on composite materials are necessary components for geometrically complex systems such as wearable devices or soft robots. Composite materials consisting of polymer matrices and conductive fillers have facilitated the manufacture of compliant sensors due to their potential to be scaled in printing processes. Printing composite materials generally entails the use of solvents, such as toluene or cyclohexane, to dissolve the polymer resin and thin down the material to a printable viscosity.

Roboticizing fabric by integrating functional fibers.

Fabrics are ubiquitous materials that have conventionally been passive assemblies of interlacing, inactive fibers. However, the recent emergence of active fibers with actuation, sensing, and structural capabilities provides the opportunity to impart robotic function into fabric substrates. Here we present an implementation of robotic fabrics by integrating functional fibers into conventional fabrics using typical textile manufacturing techniques.

Uniform conductivity in stretchable silicones via multiphase inclusions.

Many soft robotic components require highly stretchable, electrically conductive materials for proper operation. Often these conductive materials are used as sensors or as heaters for thermally responsive materials. However, there is a scarcity of stretchable materials that can withstand the high strains typically experienced by soft robots, while maintaining the electrical properties necessary for Joule heating (e.

Intermolecular Coulombic Decay in Endohedral Fullerene at the 4d→4f Resonance.

Intermolecular processes offer unique decay mechanisms for complex systems to internally relax. Here, we report the observation of an intermolecular Coulombic decay channel in an endohedral fullerene, a holmium nitride complex (Ho_{3}N) embedded within a C_{80} fullerene, between neighboring holmium ions, and between the holmium complex and the carbon cage. By measuring the ions and the electrons in coincidence after XUV photoabsorption, we can isolate the different decay channels, which are found to be more prevalent relative to intra-atomic Auger decay.

Cross Education Training Effects are Evident with Twice Daily, Self-Administered Band Stretch Training.

Currently there are recommendations for stretching type, repetitions and duration within a training session to improve flexibility. It is, however, unclear whether multiple daily stretch training sessions provide greater flexibility than single daily sessions. The objective was to investigate the effectiveness of single (1×day) versus twice daily (2×day) unilateral stretch training sessions on hip flexion range of motion (ROM), agonist and antagonist force and jump performance of the stretched and contralateral, non-stretched legs.

Unilateral hamstrings static stretching can impair the affected and contralateral knee extension force but improve unilateral drop jump height.

Purpose: Prolonged static stretching (SS) in isolation (no dynamic warm-up) can impair muscle performance. There are conflicting reports whether impairments are present in antagonist and contralateral muscles. The objective of this study was to assess the effect of unilateral hamstrings SS on ipsilateral stretched and contralateral limbs' strength and jump power.

A coincidence velocity map imaging spectrometer for ions and high-energy electrons to study inner-shell photoionization of gas-phase molecules.

We report on the design and performance of a double-sided coincidence velocity map imaging spectrometer optimized for electron-ion and ion-ion coincidence experiments studying inner-shell photoionization of gas-phase molecules with soft X-ray synchrotron radiation. The apparatus employs two microchannel plate detectors equipped with delay-line anodes for coincident, time- and position-resolved detection of photoelectrons and Auger electrons with kinetic energies up to 300 eV on one side of the spectrometer and photoions up to 25 eV per unit charge on the opposite side. We demonstrate its capabilities by measuring valence photoelectrons and ion spectra of neon and nitrogen and by studying channel-resolved photoelectron and Auger spectra along with fragment-ion momentum correlations for chlorine 2p inner-shell ionization of cis- and trans-1,2-dichloroethene.

Identification of absolute geometries of cis and trans molecular isomers by Coulomb Explosion Imaging.

An experimental route to identify and separate geometric isomers by means of coincident Coulomb explosion imaging is presented, allowing isomer-resolved photoionization studies on isomerically mixed samples. We demonstrate the technique on cis/trans 1,2-dibromoethene (CHBr). The momentum correlation between the bromine ions in a three-body fragmentation process induced by bromine 3d inner-shell photoionization is used to identify the cis and trans structures of the isomers.

Single-photon multiple detachment in fullerene negative ions: absolute ionization cross sections and the role of the extra electron.

We have obtained experimental photo-double- and photo-triple-detachment cross sections for the fullerene negative ion using Advanced Light Source photons of 17-90 eV. The cross sections are 2 and 2.5 times larger than those for C60 and appear to be compressed and shifted in photon energy as compared to C60.

Transient neutropenia increases macrophage accumulation and cell proliferation but does not improve repair following intratendinous rupture of Achilles tendon.

Neutrophils are the first leukocytes to invade tendons after an acute injury. They could modulate both the inflammatory response and early repair processes through the release of reactive species, cytokines, growth factors, and proteinases. However, the exact role of these cells in damaged tendons remains unclear.

Economic evaluation of a comprehensive teenage pregnancy prevention program: pilot program.

Background: Previous research has suggested that comprehensive teenage pregnancy prevention programs that address sexual education and life skills development and provide academic support are effective in reducing births among enrolled teenagers. However, there have been limited data on the costs and cost effectiveness of such programs.

Purpose: The study used a community-based participatory research approach to develop estimates of the cost-benefit of the Pathways/Senderos Center, a comprehensive neighborhood-based program to prevent unintended pregnancies and promote positive development for adolescents.

Thrombocytopenia alters early but not late repair in a mouse model of Achilles tendon injury.

Besides their hemostatic function, platelets can express key factors involved in tissue healing. However, the role of platelets in tendon healing following acute injury is poorly understood. We investigated this role by injecting male C57BL/6 mice with an antiplatelet antibody to induce thrombocytopenia.

Inner-shell photodetachment thresholds: unexpected long-range validity of the Wigner law.

Threshold behavior in inner-shell photodetachment is studied for the first time, specifically with 2-, 3-, or 4-electron emission from He- and S-. The threshold shapes are surprisingly consistent with the Wigner threshold law in all cases, despite large PCI effects observed in He-. In S-, the s-wave law is observed to agree with the data over an unprecedented range, more than an order of magnitude greater than predictions, and allows for the observation of the d-wave component.

Photoexcitation of He- hollow-ion resonances: observation of the 2s2p2 4P state.

Highly correlated states are studied in He-, a fundamental 3-electron system and prototypical negative ion. The 2s2p(2) 4P state is observed for the first time. This state is detected in a resonant simultaneous double-Auger decay of unprecedented strength.

Probing the molecular environment using spin-resolved photoelectron spectroscopy.

Angle- and spin-resolved photoelectron spectroscopy with linearly and circularly polarized synchrotron radiation were used to study the electronic structure of model triatomic molecules, hydrogen sulfide, and carbonyl sulfide. The spin-polarization measurements of the molecular field split components of the S 2p photolines revealed a strong effect of the different molecular environments. The validity of simple atomic models to explain the results is discussed.

Control of near-threshold detachment cross sections via laser polarization.

The behavior of near-threshold cross sections for dissociation of a target into a pair of particles, as described by Wigner's threshold law, can depend sensitively on the angular momentum of the particles. In this Letter, we investigate the near-threshold nonresonant two-photon detachment process in the negative ion of gold. The expected s-wave threshold behavior is observed with linearly polarized light.

Experimental studies of Os(-): observation of a bound-bound electric dipole transition in an atomic negative ion.

The first experimental studies of Os(-) reveal the presence of two very strong resonances. One state is a narrow shape resonance lying only 3.52(12) meV above the ground state detachment threshold, while the other is bound by 11.