Publications by authors named "Billy J Wrahatnala"

Dengue virus infection (DVI) remains a significant health challenge, and diagnosis must still be considered. Non-structural protein 1 (NS1) is a potential marker of the dengue virus that can help diagnose DVI. The study aimed to assess the role of NS1 as a predictor of the severity of DVI.

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Article Synopsis
  • * Researchers used next-generation sequencing to analyze 13 complete genomes of DENV-4 from the outbreak, focusing on its evolutionary patterns and genetic changes.
  • * Findings revealed that selection pressure and genetic mutations, along with possible recombination events in the virus, may explain DENV-4's prevalence in East Java during the outbreak.
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Outbreaks of dengue virus (DENV) in Indonesia have been mainly caused by the DENV serotype-1; -2; or -3. The DENV-4 was the least-reported serotype in Indonesia during the last five decades. We recently conducted a molecular epidemiology study of dengue in the Jember regency, East Java province, Indonesia.

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