Identifying Comorbidity Patterns in People with and without Alzheimer's Disease Using Latent Dirichlet Allocation.

Background: Multimorbidity is common in older adults and complicates diagnosing and care for this population.

Objective: We investigated co-occurrence patterns (clustering) of medical conditions in persons with Alzheimer's disease (AD) and their matched controls.

Methods: The register-based Medication use and Alzheimer's disease study (MEDALZ) includes 70,718 community-dwelling persons with incident AD diagnosed during 2005-2011 in Finland and a matched comparison cohort.