The natural history of autoimmune hepatitis presenting with jaundice.

Background: Forty percent of patients with autoimmune hepatitis (AIH) present with acute jaundice/hepatitis. Such patients, when treated promptly, are thought to have a good prognosis.

Objectives: The objective of this study was to describe the natural history of AIH in patients presenting with jaundice/hepatitis and to determine whether the diagnosis could have been made earlier, before presentation.

The management of low-risk primary upper gastrointestinal haemorrhage in the community: a 5-year observational study.

Background: Acute upper gastrointestinal haemorrhage is a common medical emergency, initially managed with inpatient care. Bleeding stops spontaneously in over 80% of cases, indicating that patients with low-risk upper gastrointestinal haemorrhage may be more optimally managed in the community, without the need for admission to hospital.

Aim: To assess the safety of managing patients with low-risk upper gastrointestinal haemorrhage without admission to hospital.