Publications by authors named "Bill P Crider"
Article Synopsis
- * The study examined the genetic diversity within the TAS2R30-46 gene region in Caucasian subjects, finding multiple mutations that influence taste responses but also indicating that many associations found might be misleading due to high linkage disequilibrium (LD).
- * Haplotype analyses and functional tests confirmed that some mutations in TAS2R31 significantly affect taste response, suggesting that various TAS2R genes might work closely together, complicating our understanding of bitter taste perception across different compounds.
Congenital heart disease (CHD) is the most common type of birth defect, and the etiology of most cases is unknown. CHD often occurs in association with other birth malformations, and only in a minority are disease-causing chromosomal abnormalities identified. We hypothesized that children with CHD and additional birth malformations have cryptic chromosomal abnormalities that might be uncovered using recently developed DNA microarray-based methodologies.
View Article and Find Full Text PDFVacuolar-type H+-translocating ATPases (V-ATPases or V-pumps) are complex proteins containing multiple subunits and are organized into two functional domains: a peripheral catalytic sector V1 and a membranous proton channel V0. The functional coupling of ATP hydrolysis activity to proton transport in V-pumps requires a regulatory component known as subunit H (SFD) as has been shown both in vivo and in vitro (Ho, M. N.
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