COLLATERAL DAMAGE: Implies negative ecological effects of antibiotic therapy, characterized by the selection of resistant microorganisms and adverse colonization or injections with their multi-resistant species. MICROBIAL RESISTANCE: Is mediated by various mechanisms, the presence of which is determined by the nature of antibiotic effects and origin of the agent. Its most important aspect is multiple resistance, most commonly conditioned by the presence of several different resistance genes localized in the form of common units on gene transport elements (integrons, transposons, plasmids).
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