Publications by authors named "Bilguel Mete"

This study primarily aimed to examine the significance of the C-reactive protein to lymphocyte ratio (CLR), a key marker of inflammation, in relation to the disease progression and management of COVID-19 patients admitted to the intensive care unit (ICU). A total of 464 patients aged 18 years or older, diagnosed with COVID-19 and admitted to the ICU between April 1, 2021, and February 1, 2022, were included in the study. Sociodemographic, laboratory, radiological, and clinical data were collected for each patient.

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Objectives: An update of the first European Society of Musculoskeletal Radiology (ESSR) consensus on soft tissue tumor imaging in 2015 became necessary due to technical advancements, further insights into specific entities, and the revised WHO classification (2020) and AJCC staging system (2017). The third part of the revised guidelines covers algorithms and techniques beyond initial imaging: (1) Imaging after neoadjuvant therapy in soft tissue sarcoma, (2) sarcoma surveillance, and (3) special aspects, including surveillance of non-malignant entities and the role of interventional radiology.

Materials And Methods: A validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries.

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Purpose: Tethered cord syndrome (TCS) typically presents with urologic symptoms and abnormal imaging findings. However, some patients present with normal conus medullaris level and filum terminale appearance on MRI. This research seeks to assess the intended surgical results in this particular group of TCS patients who do not present with urologic complaints, under the premise that the surgical approach goes a long way in preventing the onset of urologic abnormalities.

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Objective: This study aimed to explore the relationship between fluorine-18-fluorodeoxyglucose (F-FDG) uptake in the liver, spleen, and bone marrow and inflammatory markers such as c-reactive protein (CRP), albumin, and erythrocyte sedimentation rate (ESR) in patients undergoing positron emission tomography/computed tomography (PET/CT) imaging for cancer diagnosis.

Subjects And Methods: This retrospective cross-sectional study included a total of 708 patients with a diagnosis of malignancy. Fluorine-18-FDG PET/CT images acquired between January 2021 and December 2022.

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  • This study focuses on identifying extraprostatic extension (EPE) in prostate cancer patients using advanced imaging techniques, highlighting its importance for treatment outcomes.
  • Researchers analyzed MRI scans from 20 patients who underwent surgery, extracting over 200 radiomic features to help differentiate between EPE and non-EPE lesions.
  • The results showed that an MLP neural network model using 18 key features could accurately predict EPE, achieving a sensitivity of 75%, specificity of 79%, and an area-under-curve (AUC) of 0.82, indicating promising predictive capability.
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  • Chronic obstructive pulmonary disease (COPD) often leads to hospital readmissions, with a study involving 415 patients in Turkey revealing significant readmission rates of 42.4% within 30 days and 46% within 90 days after severe exacerbations.
  • Key risk factors for 30-day readmissions include high anxiety and depression scores, a history of severe exacerbations, hospital-acquired pneumonia, and frequent antibiotic use.
  • For 90-day readmissions, factors such as severe heart regurgitation, multiple moderate exacerbations, immunosuppression, and being hospitalized via the emergency department were significant contributors.
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  • * These tumors have a potential risk of metastasis and the 2022 WHO classification emphasizes combining morphology with functional and genetic studies for more accurate diagnosis and prognosis.
  • * This review aims to update pathologists on modern diagnostic strategies, focusing on biomarkers and genetic profiling, while addressing challenges in identifying metastatic disease.
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: One of the most critical problems regarding sarcopenia is the difficulty of the diagnosis process. This study aimed to determine the prevalence and investigate the role of serum beta-2 microglobulin level as a biomarker for diagnosing sarcopenia. : This nested case-control study was conducted between 2023 and 2024 on 251 older adults.

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  • Thyroid cancer management is evolving with the use of actionable biomarkers from genetic testing, which helps guide treatment decisions for patients.
  • An expert panel developed consensus algorithms and recommendations for testing specific types of thyroid cancer to improve patient care and address existing disparities in biomarker testing.
  • The recommendations aim to assist physicians in effectively navigating the complexities of thyroid cancer biomarker testing while considering financial and practical constraints, ensuring a multidisciplinary approach for optimal treatment.
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Tumors of adenohypophysial hormone-secreting cells, now classified as pituitary neuroendocrine tumors (PitNETs), have been subclassified based on cell differentiation. Normal adenohypophysial cells have three lineages of differentiation driven by the transcription factors PIT1, TPIT, and SF1 which are responsible for the regulation of hormone gene expression; PIT1 drives expression of GH, PRL, and TSH, TPIT is required for POMC expression that gives rise to ACTH, and SF1 is the transcription factor responsible for FSH and LH expression. The vast majority of PitNETs follow these three lineage differentiation pathways but rare PitNETs show either no lineage differentiation or express biomarkers of more than one lineage.

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Objectives: Mental health (MH) care for people living with HIV (PLWH) emerges as an important unmet need, yet there are no integrated HIV-MH clinics in Turkey. Our aim is to determine MH service use and its associated factors in PLWH followed up in the HIV/AIDS outpatient clinics in Istanbul/Turkey.

Methods: A cross-sectional study was conducted at the HIV/AIDS outpatient clinics of the Infectious Diseases (ID) departments in hospitals affiliated with the ACTHIV-IST Study Group.

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Most follicular cell-derived differentiated thyroid carcinomas are regarded as low-risk neoplasms prompting conservative therapeutic management. Here, we provide consensus recommendations reached by a multidisciplinary group of endocrinologists, medical oncologists, pathologists, radiation oncology specialists, a surgeon and a medication reimbursement specialist, addressing more challenging forms of this malignancy, focused on radioactive iodine (RAI)-resistant or -refractory differentiated thyroid carcinoma (RAIRTC). In this document we highlight clinical, radiographic, and molecular features providing the basis for these management plans.

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: Hemodialysis treatment for acute kidney injury associated with crush syndrome is very complex. In our study, we summarized the problems and complications experienced by our hemodialysis center after the Kahramanmaraş earthquake. : After the earthquake, our hospital treated 1396 victims.

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A search for the exclusive hadronic decays W^{±}→π^{±}γ, W^{±}→K^{±}γ, and W^{±}→ρ^{±}γ is performed using up to 140  fb^{-1} of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of sqrt[s]=13  TeV. If observed, these rare processes would provide a unique test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders. Additionally, at future colliders, these decays could offer a new way to measure the W boson mass through fully reconstructed decay products.

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  • - The ATLAS experiment at the LHC conducted a search for long-lived particles (LLPs) using a large dataset (140 fb^{-1}) from proton-proton collisions at 13 TeV, focusing on LLPs with masses from 5 to 55 GeV that decay within the inner detector.
  • - The study considered scenarios where LLPs are produced from exotic Higgs boson decays and models involving axionlike particles (ALPs).
  • - No significant findings above expected background levels were detected, leading to the establishment of upper limits on various production rates involving the Higgs boson and the top quark related to LLPs and ALPs.
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Aim: To retrospectively evaluate the cranial magnetic resonance imaging (MRI) features and determine the incidence of intracranial arachnoid cysts (ACs) based on sex, age, location, size, affected side, Galassi type, and their association with hydrocephalus, mega cisterna magna (MCM), bone erosion, and midline brain shift in 15,108 patients during outpatient headache evaluations.

Material And Methods: Between 2012 and 2022, cranial MRI scans of 15,108 adult patients aged 20-70 years undergoing outpatient evaluations for headaches were retrospectively reviewed to analyze the features of ACs detected incidentally. Patients who had previously undergone a craniotomy or craniectomy were excluded from the study.

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Objective: Large language models (LLMs) are used in various fields for their ability to produce human-like text. They are particularly useful in medical education, aiding clinical management skills and exam preparation for residents. To evaluate and compare the performance of ChatGPT (GPT-4), Gemini, and Bing with each other and with otorhinolaryngology residents in answering in-service training exam questions and provide insights into the usefulness of these models in medical education and healthcare.

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Background: Patients increasingly use chatbots powered by artificial intelligence to seek information. However, there is a lack of reliable studies on the accuracy and reproducibility of the information provided by these models. Therefore, we conducted a study investigating the ChatGPT's responses to questions about otosclerosis.

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We have warmly welcomed the opportunity to propose the Special Issue titled "Novel Diagnosis and Therapeutics Approaches in Retina Diseases", and numerous authors have decided to submit their works to it [...

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  • The study focuses on tendon injuries in complex wounds of the hand and lower extremities, exploring how different types of adipofascial tissue flaps affect healing and functional recovery.
  • It compares vascularised versus nonvascularised adipofascial flaps using Wistar Albino rats, assessing healing through scintigraphic evaluations and histopathological analysis.
  • Results indicate that vascularised flaps promote faster healing while pedicle-free flaps also aid tendon recovery without complications, providing insights for improving tendon repair techniques in reconstructive surgery.
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