Feasibility of totally extraperitoneal inguinal hernia repair in patients with previous prostatectomy.

Objectives: Laparoscopic totally extraperitoneal inguinal hernia repair (TEP) surgery technique includes three key steps: reaching the preperitoneal space, reducing hernias, and placement of mesh. However, reaching the preperitoneal space can be complicated in patients with previous lower abdominal surgeries. This study aimed to assess the feasibility of laparoscopic inguinal TEP in patients with previous prostatectomies.

Efficacy of Amikacin and Meropenem on Colistin-Induced Persisters.

Colistin-based antibiotic therapies have been recommended for the treatment of multidrug-resistant infections. During colistin treatment, persister cells that tolerate antibiotics may arise. Here we designed an study to assess the killing activity of colistin, meropenem, and amikacin on colistin-induced persisters in comparison with starvation-induced persisters.

Virulence Determinants of Colistin-Resistant High-Risk Clones.

We proposed the hypothesis that high-risk clones of colistin-resistant (ColR-Kp) possesses a high number of virulence factors and has enhanced survival capacity against the neutrophil activity. We studied virulence genes of ColR-Kp isolates and neutrophil response in 142 patients with invasive ColR-Kp infections. The ST101 and ST395 ColR-Kp infections had higher 30-day mortality (58%, = 0.