Synthesis, Physicochemical Characterization, Biological Evaluation, In Silico and Molecular Docking Studies of Pd(II) Complexes with P, S-Donor Ligands.

One homoleptic () and three heteroleptic (-) palladium(II) complexes were synthesized and characterized by various physicochemical techniques, i.e., elemental analysis, FTIR, Raman spectroscopy, H, C, and P NMR.

Cefepime Population Pharmacokinetics, Antibacterial Target Attainment, and Estimated Probability of Neurotoxicity in Critically Ill Patients.

Cefepime has been reported to cause concentration-related neurotoxicity, especially in critically ill patients with renal failure. This evaluation aimed to identify a dosing regimen providing a sufficient probability of target attainment (PTA) and the lowest justifiable risk of neurotoxicity in critically ill patients. A population pharmacokinetic model was developed based on plasma concentrations over four consecutive days obtained from 14 intensive care unit (ICU) patients.

Examining health professional perspectives on social media body image movements: A qualitative exploration.

There has been a lack of investigation into the understanding of social media body image movements from the healthcare perspective. Health professionals can have a strong influence on how their patients relate to their own bodies, including experiences of weight-based discrimination. This study examined the perspectives of health professionals on body image social media movements and whether they believed they were relevant to their professional practice.

Long-term PM pollution over China: Identification of PM pollution hotspots and source contributions.

Fine particulate matter, with an aerodynamic diameter ≤ 2.5 μm (PM), is a severe problem in China. The lack of ground-based measurements and its sparse distribution obstruct long-term air pollution impact studies over China.

Corrigendum: Strontium-doped chromium oxide for RhB reduction and antibacterial activity with evidence of molecular docking analysis.

[This corrects the article DOI: 10.3389/fchem.2023.

Sequence Variants in and Underlying Syndactyly.

Introduction: Syndactyly is a common congenital limb malformation. It occurs due to embryological failure of digit separation during limb development. Syndactyly often runs in families with an incidence of about one out of every 2,500-3,000 live births.

Estimating ground-level PM using subset regression model and machine learning algorithms in Asian megacity, Dhaka, Bangladesh.

Unlabelled: Fine particulate matter (PM) has become a prominent pollutant due to rapid economic development, urbanization, industrialization, and transport activities, which has serious adverse effects on human health and the environment. Many studies have employed traditional statistical models and remote-sensing technologies to estimate PM concentrations. However, statistical models have shown inconsistency in PM concentration predictions, while machine learning algorithms have excellent predictive capacity, but little research has been done on the complementary advantages of diverse approaches.

Laser flash photolysis study of NbO/g-CN heterostructures as efficient photocatalyst for molecular H evolution.

Improvements of visible light activity, slow recombination rate, stability, and efficiency are major challenges facing photocatalyst technologies today. Utilizing heterostructures of g-CN (bandgap ∼2.7eV) with NbO (bandgap ∼3.

Diphtheria: The rising cases of "Throat Distemper" in Pakistan: A short communication.

Background: The objective of this short communication is to summarize the current situation in Pakistan regarding the rising cases of diphtheria and to emphasize the need for public health interventions to control the spread of the disease.

Study Design: This study is a short communication.

Methods: Data on diphtheria cases were collected from various sources including the Pakistan Ministry of Health, the World Health Organization (WHO), and media reports.

Effects of microplastics in freshwater fishes health and the implications for human health.

The presence of microplastics in aquatic environments has raised concerns about their abundance and potential hazards to aquatic organisms. This review provides insight into the problem that may be of alarm for freshwater fish. Plastic pollution is not confined to marine ecosystems; freshwater also comprises plastic bits, as the most of plastic fragments enter oceans via rivers.

Analysis of Reported Adverse Events Related to Hemospray: An FDA MAUDE Database Study.

Background: Topical hemostatic powder is a mineral powder that forms an adherent barrier and coagulates active bleeding in the gastrointestinal (GI) tract. Hemospray is the first hemostatic powder approved by the Food and Drug Administration (FDA) in the United States. Hemospray has been increasingly used to manage GI bleeding.

Metabolic Degradation and Bioactive Derivative Synthesis of Phenazine-1-Carboxylic Acid by Genetically Engineered HT66.

Phenazine-1-carboxylic acid (PCA) secreted by has been commercialized and widely employed as an antifungal pesticide. However, it displays potential hazards to nontarget microorganisms and the environment. Although the PCA degradation characteristics have received extensive attention, the biodegradation efficiency is still insufficient to address the environmental risks.

Pharmacophore-Based Virtual Screening and In-Silico Explorations of Biomolecules (Curcumin Derivatives) of as Potential Lead Inhibitors of ERBB and VEGFR-2 for the Treatment of Colorectal Cancer.

The newly FDA-approved drug, Axitinib, is an effective therapy against RTKs, but it possesses severe adverse effects like hypertension, stomatitis, and dose-dependent toxicity. In order to ameliorate Axitinib's downsides, the current study is expedited to search for energetically stable and optimized pharmacophore features of 14 curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione) derivatives. The rationale behind the selection of curcumin derivatives is their reported anti-angiogenic and anti-cancer properties.

An Accurate and Inter-Operatable Fuzzy-Based System Using Genetic and Canonical Correlation Analysis Methods in Internet-of-Brain Things.

The brain computer interface is defined as the way of acquiring the brain signals that analyse and translates them into commands that are relayed to intelligent devices for carrying out various actions. Through number of BCI mechanism and approaches have been proposed by various scientists to empower the individuals for directly controlling their objects via their thoughts. However, the actual implementation and realization of this method faces number of challenging with low accuracy and less interoperability.

Structural insights, biocatalytic characteristics, and application prospects of lignin-modifying enzymes for sustainable biotechnology.

Lignin modifying enzymes (LMEs) have gained widespread recognition in depolymerization of lignin polymers by oxidative cleavage. LMEs are a robust class of biocatalysts that include lignin peroxidase (LiP), manganese peroxidase (MnP), versatile peroxidase (VP), laccase (LAC), and dye-decolorizing peroxidase (DyP). Members of the LMEs family act on phenolic, non-phenolic substrates and have been widely researched for valorization of lignin, oxidative cleavage of xenobiotics and phenolics.

Identification and functional analysis of non-coding regulatory small RNA FenSr3 in LPB-18.

is an interesting microbe in the food processing and manufacturing industries. Non-coding small RNAs (sRNAs) have been shown to play a crucial role in the physiology and metabolism of bacteria by post-transcriptionally regulating gene expression. This study investigated the function of novel sRNA FenSr3 by constructing deficient strain and complementary strains in LPB-18 , which were named LPN-18N and LPB-18P, respectively.

Iatrogenic Cardiac Tamponade Secondary to Central Venous Catheter Placement: A Literature Review.

Cardiac tamponade is the fluid accumulation within the pericardial sac that compresses the heart and decreases cardiac output. More than 20% of the cases are surgical or non-surgical iatrogenic causes. Cardiac tamponade has been described as a rare complication of central venous catheter placement with an incidence in adults as low as less than 1% but with significantly high mortality of more than 60%.

Comparative appraisal of mono and hybrid nanofluid flows comprising carbon nanotubes over a three-dimensional surface impacted by Cattaneo-Christov heat flux.

Carbon nanotubes (CNTs) are nanoscale tubes made of carbon atoms with unique mechanical, electrical, and thermal properties. They have a variety of promising applications in electronics, energy storage, and composite materials and are found as single-wall carbon nanotubes (SWCNTs) and double-wall carbon nanotubes (DWCNTs). Considering such alluring attributes of nanotubes, the motive of the presented flow model is to compare the thermal performance of magnetohydrodynamic (MHD) mono (SWCNTs)/Ethylene glycol) and hybrid (DWCNTs- SWCNTs/Ethylene glycol) nanofluids over a bidirectional stretching surface.

Use of the endoscopic powered resection device for the management of scarred polyps.

Background And Aims: The endoscopic powered resection (EPR) device (EndoRotor, Interscope Inc, Northbridge, Mass, USA) is a novel nonthermal device that can be used for polyp and tissue removal in the GI tract. Here, we review the EPR device and illustrate its use for resection of scarred or fibrotic lesions in the GI tract.

Methods: In this article and accompanying video, we describe the EPR device features, provide step-by-step instructions for device setup, and review case examples in which the EPR device was used for scarred polyp resection.

Isolation of a potential probiotic strain LPB-18 and identification of antimicrobial compounds responsible for inhibition of food-borne pathogens.

This study was carried out to screen a potential probiotic microbe with broad-spectrum antagonistic activity against food-borne pathogens and identify the antimicrobial compounds. Based on morphological and molecular analysis, a new strain with the ability to produce effective antimicrobial agents was isolated from the breeding soil of earthworms and identified as having a close evolutionary footprint to . The antimicrobial substances produced by show effective inhibition of and in an agar diffusion assay.