[Sensitivity of Helicobacter pylori to antibacterial drug preparations in potential military recruits with duodenal peptic ulcer].

Results are submitted of bacteriological investigations in those persons with duodenal peptic ulcer who had been called up. The presence of regional strains of H. pylori is ascertained together with their sensitivity to certain antibacterial drug preparations.

Specific identification of Mycobacterium bovis by monoclonal antibody-based enzyme immunoassay.

To improve identification of M. bovis, rabbit immune sera and mouse monoclonal antibodies against M. bovis-secreted protein antigens were used in the enzyme-linked assay (ELISA).

[A chamber for microorganism microcultivation with microscopic monitoring].

A new chamber for microorganism microcultivation with microscopic monitoring has been developed and tried. It is not only fit for microcultivation of various microorganism species but is characterized by a number of advantages over the known chambers as well.

[A new method of cultivating Mycobacterium tuberculosis].

The possibility is shown of microcultivation of Mycobacteria tuberculosis on semipermeable cellophane membranes covering solid nutrients. The new method of cultivation may be used for enhanced microbiological diagnosis of tuberculosis, for determination of drug resistance of the tuberculous pathogen as well as for assessment of the biological properties of Mycobacteria tuberculosis in live unstained culture.

[Microscopic method of the determination of Mycobacterium tuberculosis sensitivity to chemotherapeutic agents].

A microscopic method of testing M. tuberculosis sensitivity to chemotherapeutic drugs was developed and tried out. According to it, M.

[Method of combined micro- and macrocultivation of Mycobacterium tuberculosis in egg medium using agar gel disks].

A procedure for combined micro- and macrocultivation of tubercle bacilli in the egg media by using agar gel disks was developed and experimentally tested. The essence of the procedure lies in plating mycobacteria on agar gel disks applied to the egg medium in Petri dishes followed by incubation at 37 degrees C for 5-7 days. Later on the agar gel disks are removed from the medium and examined microscopically for growth of tubercle bacilli in microcolonies (microcultivation).

[Experimental study of the antibiotic activity of cefuroxime].

The antimicrobial spectrum of cefuroxime, an antibiotic of the cephalosporin family was studied in vitro with respect to 11 species (16 strains) of gram-positive and gram-negative bacteria and in vivo on albino mice with experimental salmonellosis or pneumococcal infections. The bacteria were either test cultures or isolates from patients. The studies showed that cefuroxime had a wide antibacterial spectrum in vitro.