Publications by authors named "Bikranta Bikram Kharel"
JNMA J Nepal Med Assoc
May 2024
Article Synopsis
- - A 61-year-old male experienced a persistent fever for three months, leading to a diagnosis of hemophagocytic lymphohistiocytosis after a liver biopsy and positron-emission tomography showed abnormal lesions in the liver.
- - Common symptoms of this condition include fever, an enlarged spleen, high levels of ferritin and triglycerides, elevated liver enzymes, and signs of hemophagocytosis in the bone marrow.
- - Treatment options generally involve systemic corticosteroids, chemotherapy, cyclosporine, or hematopoietic stem cell transplantation, but there's a concern that this diagnosis can be overlooked in resource-limited settings like Nepal, so doctors should consider it in cases of unexplained fever.
