Critical review on plant-derived quorum sensing signaling inhibitors in pseudomonas aeruginosa.

Pseudomonas aeruginosa, a biofilm-forming organism with complex quorum mechanisms (Las, Rhl, PQS, and IQS), poses an imminent danger to the healthcare sector and renders current treatment options for chemotherapy ineffectual. The pathogen's diverse pathogenicity, antibiotic resistance, and biofilms make it difficult to eradicate it effectively. Quorum sensing, a complex system reliant on cell density, controls P.

A review of chemical signaling mechanisms underlying quorum sensing and its inhibition in Staphylococcus aureus.

Staphylococcus aureus is a significant bacterium responsible for multiple infections and is a primary cause of fatalities among patients in hospital environments. The advent of pathogenic bacteria such as methicillin-resistant S. aureus revealed the shortcomings of employing antibiotics to treat bacterial infectious diseases.

Effect of cooking on nutrient composition and anticancer indoles of the marine whelk Dicathais orbita - Can it be another high-value seafood product?

The Australian marine mollusc Dicathais orbita has been identified as a functional food with potential for use in the prevention of colon cancer. This study investigated the effect of cooking on the biochemical profile of the edible flesh and extracts containing anticancer brominated indoles. The whelk flesh was high in protein (>75 mg/100 mg dry weight) and there was a significant increase in protein and amino acids after cooking, associated with a loss of moisture and lipids.

Volatile and bioactive compounds in opercula from Muricidae molluscs supports their use in ceremonial incense and traditional medicines.

Muricidae molluscs are the source of a valuable purple dye that was traded as a luxury item in the Mediterranean region and by the late Byzantine was reserved for royalty and priests. Less well known is the use of muricid opercula in sacred incense and traditional medicines, although they are still used as rare ingredients today. This study provides the first chemical assessment of opercula from Muricidae, based on several traditional preparation procedures.

Are the Traditional Medical Uses of Muricidae Molluscs Substantiated by Their Pharmacological Properties and Bioactive Compounds?

Marine molluscs from the family Muricidae hold great potential for development as a source of therapeutically useful compounds. Traditionally known for the production of the ancient dye Tyrian purple, these molluscs also form the basis of some rare traditional medicines that have been used for thousands of years. Whilst these traditional and alternative medicines have not been chemically analysed or tested for efficacy in controlled clinical trials, a significant amount of independent research has documented the biological activity of extracts and compounds from these snails.