Publications by authors named "Bijay Mukesh Jeswani"

Article Synopsis
  • * A systematic review and meta-analysis of studies showed no significant differences in major cardiac events between the two treatment types, but revealed potential benefits of conservative care in reducing specific complications.
  • * The results suggest that while both approaches appear similar in overall outcomes, conservative treatment notably reduced rates of inferior wall STEMI and heart failure compared to revascularization methods.
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Objective: Giant cell arteritis (GCA) is a chronic inflammatory condition associated with a significantly increased risk of various cardiovascular and thromboembolic events. Existing studies suggest an increased risk of cardiovascular disease in GCA, but results vary. This meta-analysis aims to quantify the association between GCA and the risk of various cardiovascular outcomes, providing a comprehensive evaluation of the cardiovascular burden in patients with GCA.

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Introduction: PCSK9 inhibitors are a novel class of medications that lower LDL cholesterol (LDL-C) by increasing LDL receptor activity, promoting clearance of LDL-C from the bloodstream. Over the years, PCSK9 inhibitors have been explored as adjunct therapies to statins or as monotherapy in high-risk cardiovascular patients.

Aim: This review aims to provide an updated perspective on PCSK9 inhibitors, assessing their clinical efficacy, safety, and significance, especially in light of recent clinical trials.

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Article Synopsis
  • * A meta-analysis of 21 articles involving 26,933 COVID-19 patients found a UGIB prevalence of 2.10%, with significant rates of severity (55%), mortality (29%), and rebleeding (12.7%).
  • * UGIB in COVID-19 patients is associated with worse outcomes, showing increased odds of severe illness (3.52 times) and higher mortality (2.16 times) compared to those without UGIB, emphasizing the need for prompt clinical attention.
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