Survival analysis in gastric cancer: a multi-center study among Iranian patients.

Background: Gastric cancer (GC) has been considered as the 5th most common type of cancer and the third leading cause of cancer-associated death worldwide. The aim of this historical cohort study was to evaluate the survival predictors for all patients with GC using the Cox proportional hazards, extended Cox, and gamma-frailty models.

Methods: This historical cohort study was performed according to documents of 1695 individuals having GC referred to three medical centers in Iran from 2001 to 2018.

Psychological features in patients with and without irritable bowel syndrome: A case-control study using Symptom Checklist-90-Revised.

Context: Recent studies have demonstrated that a high proportion of irritable bowel syndrome (IBS) patients shows an association with psychological factors. A few studies were conducted on the investigation of psychological features of IBS patients in Iran.

Aims: We aimed to evaluate the relationship of psychological distress with IBS in outpatient subjects.

Evaluation of the benefit of addition of clidinium C to a Helicobacter pylori eradication regimen.

Aim: This study aimed to evaluate the success of H.pylori eradication therapy in patients with dyspepsia by therapeutics regimes with and without clidinium C.

Background: Helicobacter pylori infections are reported in all parts of the world.

Anxiety and depression in a sample of Iranian patients with irritable bowel syndrome.

Objective: Previous studies have shown that up to 50% to 70% of patients with irritable bowel syndrome (IBS) who seek treatment have psychiatric comorbidity. The aim of this study was to report the history of anxiety and depression in IBS patients.

Methods: The study, designed as a cross-sectional, was performed in a consecutive sample of individuals diagnosed with IBS in the Gastroenterology Clinic of Taleghani Hospital, Tehran province, Iran from October 2010 to October 2011.

Determinants of Physical Health of Older People in Iran.

Background. Many of the older people are encountered with physical and mental health problems, chronic diseases, and also living conditions. We aimed to evaluate the disability scores and its associated factors among a sample of older people in Iran.

Direct medical care costs associated with patients diagnosed with chronic HCV.

Background: HCV virus (HCV) is a significant global problem with wide-ranging socio-economic impacts. Because of the high morbidity and mortality associated with end-stage liver disease, cirrhosis, and hepatocellular carcinoma (HCC), the economic burden of HCV infection is substantial.

Objectives: This study aimed to estimate the direct medical care costs of chronic HCV infection.

The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial.

Aim: Evaluating the efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of Helicobacter pylori.

Background: Several probiotics such as Saccharomyces boulardii have been investigated for their clinical efficacy. This probiotic, inhibit H.

Specific count model for investing the related factors of cost of GERD and functional dyspepsia.

Aim: The purpose of this study is to analyze the cost of GERD and functional dyspepsia for investing its related factors.

Background: Gastro-oesophageal reflux disease GERD and dyspepsia are the most common symptoms of gastrointestinal disorders. Recent studies showed high prevalence and variety of clinical presentation of these two symptoms imposed enormous economic burden to the society.

Evaluation of psychological aspects among subtypes of irritable bowel syndrome.

Context: While some studies have found disparities between subtypes of irritable bowel syndrome (IBS), others did not found such differences.

Aim: This study aimed to investigate whether there are differences in psychological features between the subtypes of IBS.

Settings And Design: A cross-sectional study was performed on all consecutive outpatients IBS diagnosed (from Oct.

Increased oesophageal cancer mortality rate in Iran.

Background And Study Aims: The aim of this study is to present the mortality trends of oesophageal cancer (EC) in the Iranian population, to provide updated information regarding time trends for this cancer.

Patients And Methods: We analysed the national death statistics reported by the Iranian Ministry of Health and Medical Education from 1995 to 2004. EC [International Classification of Diseases (ICD-9); C15] were expressed as the annual mortality rates/100000, overall, by sex and by age group (<15, 15-49 and ≥ 50 years of age) and age standardised rate (ASR).

Four years incidence rate of colorectal cancer in Iran: a survey of national cancer registry data - implications for screening.

Introduction: Design and implementation of screening programs in each country must be based on epidemiological data. Despite the relatively high incidence of CRC, there is no nationwide comprehensive program for screening in Iran. This study was designed to investigate national CRC data and help to determine guidelines for screening.

Estimation of average diagnosis and treatment costs of hepatitis C.

Aim: The objective of this study was to estimate the average cost of diagnosis and treatment of hepatitis C among patients based on their treatment regime, during the one course of treatment and six-month after stopping that.

Background: Hepatitis C virus (HCV) infection is a major cause of liver-related morbidity and mortality worldwide and a major public health problem.

Patients And Methods: All data for this cross-sectional study were collected from medical records of 200 patients with hepatitis C, who referred to a private gastroenterology clinic between years 2005 through 2009.

Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: overlap analysis using loglinear models.

Background And Study Aims: Irritable bowel syndrome (IBS), gastro-oesophageal reflux disease (GERD) and dyspepsia are three most important gastrointestinal disorders which occur frequently together in patients. This study aims to assess the association between IBS, GERD and dyspepsia by using loglinear model analysis.

Patients And Methods: This cross-sectional household survey, the purpose of which was to find the prevalence of gastrointestinal symptoms, disorders and the related factors, has been done from May 2006 to December 2007 in Tehran province, Iran.

An overview of colorectal cancer survival rates and prognosis in Asia.

Colorectal cancer is a rapidly rising trend in Asia. The incidence in many Asian countries is on par with the West. Several studies have provided data regarding the survival of patients with colorectal cancer.

History of upper gastrointestinal cancers in relatives: a community-based estimate.

Aim: The present study aimed to evaluate the prevalence of positive family history of these cancers in a large population-based sample of Tehran province, capital of Iran.

Background: Upper gastrointestinal (UGI) cancers (gastric and esophagus cancer) constitute a major health problem worldwide. A family history of cancer can increase the risk for developing cancer and recognized as one of the most important risk factors in predicting personal cancer risk.

Using statistical models to assess medical cost of hepatitis C virus.

Aim: This study compared PR and NB in predicting HCV patient costs. The objective of this study was to predict the direct cost of the HCV patient in Iran.

Background: Hepatitis C virus (HCV) is a common and expensive infectious disease in Iran.

Epidemiological features of gastro-esophageal reflux disease in Iran based on general population.

Aim: The aim of this study was to evaluate the epidemiology of GERD base on population study in Tehran providence.

Background: Gastro-esophageal reflux disease (GERD) is a common and chronic problem. Recent reports from developing countries indicate increment in the incidence and prevalence of the disease over the past.

Economic burden attributable to functional bowel disorders in Iran: a cross-sectional population-based study.

Objective: While few population-based studies on the economic burden of functional bowel disorders (FBD) have been published from developing countries like Iran, this study aimed to estimate their direct and indirect costs for five groups of patients: irritable bowel syndrome (IBS), functional constipation (FC), unspecified-FBD (U-FBD), functional abdominal bloating (FAB) and functional diarrhea (FD).

Methods: Up to 18,180 adults randomly sampled from Tehran, Iran (2006-2007) were interviewed using two questionnaires based on the Rome III criteria to detect FBD patients and to estimate their medical expenses (such as visiting the doctor, drugs, hospitalization and laboratory tests) and productivity loss in the previous 6 months. All costs were converted to dollar purchasing power parity (PPP$) to facilitate cross-country comparisons.

Economic burden of gastro-oesophageal reflux disease and dyspepsia: A community-based study.

Background And Study Aims: Gastro-oesophageal reflux disease (GERD) and dyspepsia are common digestive disorders that inflict serious harm, burden and economic consequences on individuals worldwide. The aim of this study was to estimate the direct and indirect economic burden of GERD and dyspepsia in the whole population of Tehran, the capital of Iran.

Patients And Methods: The study was performed on a total of 18,180 adult subjects (age>18 years) taken as a random sample in Tehran province, Iran (2006-2007).

Familial prevalence of cancer in Iran: a general population estimate.

Background: Having a family history (FH) of cancer is recognized as one of the most important factors in predicting personal cancer risk. Since reports on cancer FH from developing countries are limited, the present study was conducted to provide a first report on the prevalence of familial cancers in Iran.

Methods: Cross-sectional analysis performed on self-reported FH of cancers based on data from a large population based study in Tehran, the capital of Iran.

Decreased trend of pancreatic cancer mortality in iran.

Background: Pancreatic cancer is a fatal cancer with a 5-year survival of only about 4% for all tumors. There are only published data on mortality from pancreas cancer and its epidemiology in Iran. The aim of this study was to present the mortality trends from pancreatic cancer for the Iranian population, using national death statistics in order to provide update information for its burden.

Bloating in irritable bowel syndrome.

Aim: The purpose of this study was to describe the occurrence of self report bloating and related factors in patients with irritable bowel syndrome (IBS).

Background: Bloating symptoms are common in patients with IBS and have significant impact on normal daily function.

Patients And Methods: This study was a community-based cross-sectional survey that conducted using a valid questionnaire base on Rome III criteria.

Characteristics of colorectal mucinous adenocarcinoma in Iran.

Aims And Background: Mucinous adenocarcinoma (MA) colorectal cancer accounts for 10 to 15% of colorectal carcinoma. It is generally thought that patients with MA present at a more advanced stage of disease and have a poorer prognosis than those with other types of carcinoma. The purpose of the present study was to clarify the clinicopathological characteristics of mucinous colorectal carcinoma in the Iranian population.

Assessment the relationship between reflux and body mass index with comparing different regression models.

Aim: The aim of this study was to determine whether there is relation between body mass index and symptoms of gastro-esophageal reflux disease in our community using Logit, Probit and Complementary log-log models.

Background: The most frequent statistical tool to address the relationship among a dichotomous response and other covariates is logistic regression. However logistic regression is familiar for researchers, some other models with similar results are favorable to assess such relationship like as Probit and Complementary log-log.

Direct and indirect medical costs of functional constipation: a population-based study.

Background: Constipation causes a large number of medical visits each year and imposes significant financial toll on healthcare systems worldwide. So the present community-based study was conducted in order to estimate attributable direct and indirect costs to functional constipation (FC) and to provide an overview of related physician visits in general population of Iran.

Methods: From May 2006 to December 2007, a total of 19,200 adult persons (aged 16 and above) were drawn randomly in Tehran province, Iran (response rate 94%).