Severe sodium channel blockade and cardiovascular collapse due to a massive lamotrigine overdose.

Background: Cardiac arrest due to lamotrigine (LTG) has been reported after co-ingestion with bupropion, but severe sodium channel blockade in the absence of other toxins has not been described. We report a case of cardiac arrest and status epilepticus following a massive LTG overdose.

Case Report: A 48 year-old female was brought to the ED with seizure-like activity subsequent to ingesting 7.