Publications by authors named "Bih Hycenta Chendi"
Article Synopsis
- The study explored the effectiveness of blood-based transcriptomic signatures in diagnosing tuberculosis (TB) compared to other respiratory infections in patients hospitalized in a low-TB endemic country.
- Researchers analyzed the expression of 26 specific genes using qPCR on blood samples from 31 patients, finding a significant age difference between TB and non-TB cases and identifying a three-gene signature for TB diagnosis.
- The three-gene signature showed promising diagnostic accuracy with an AUC of 0.86, indicating good potential for future TB diagnosis, though the impact of factors like age on results needs to be investigated further in larger studies.
Cytokine profile in the sputum of subjects with post-tuberculosis airflow obstruction and in those with tobacco related chronic obstructive pulmonary disease.
BMC Immunol
October 2020
Background: Previous studies have shown that tuberculosis (TB) is a risk factor for chronic airflow limitation. Chronic obstructive pulmonary disease (COPD) is recognized as the result of chronic inflammation, usually related to noxious particles. Post-TB airflow obstruction and tobacco-related COPD have the same functional pathway characterized by persistent airflow limitation.
View Article and Find Full Text PDFRate of viral load change and adherence of HIV adult patients treated with Efavirenz or Nevirapine antiretroviral regimens at 24 and 48 weeks in Yaoundé, Cameroon: a longitudinal cohort study.
BMC Infect Dis
February 2019
Background: HIV-load decrease and suppression over time is associated with consistent adherence to antiretroviral therapy (ART). Our study aimed to evaluate the difference in viral load and adherence of patients treated with a combination of either Tenofovir (TDF), Lamivudine (3TC) and Efavirenz (EFV) or TDF / Zidovudine (AZT), 3TC and Nevirapine (NVP) regimens at 24 and 48 weeks.
Methods: A longitudinal study was conducted from May 2016 to June 2017 among 256 HIV infected adult patients who were enrolled at two approved treatment hospitals in Yaoundé, before the start of first-line ART.