Publications by authors named "Bignami Elena Giovanna"

Sepsis is one of the leading causes of mortality in hospital settings, and early diagnosis is a crucial challenge to improve clinical outcomes. Artificial intelligence (AI) is emerging as a valuable resource to address this challenge, with numerous investigations exploring its application to predict and diagnose sepsis early, as well as personalizing its treatment. Machine learning (ML) models are able to use clinical data collected from hospital Electronic Health Records or continuous monitoring to predict patients at risk of sepsis hours before the onset of symptoms.

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: There is a notable lack of protocols addressing extubation techniques in transoral robotic surgery (TORS) for obstructive sleep apnea (OSA). : This retrospective cohort study enrolled patients who underwent TORS for OSA between March 2015 and December 2021 and were managed with different extubation approaches. The patients were divided into two groups: high-flow nasal cannula (HFNC) therapy and conventional oxygen therapy.

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With the large volume of data coming from implemented technologies and monitoring systems, intensive care units (ICUs) represent a key area for artificial intelligence (AI) application. Despite the last decade has been marked by studies focused on the use of AI in medicine, its application in mechanical ventilation management is still limited. Optimizing mechanical ventilation is a complex and high-stake intervention, which requires a deep understanding of respiratory pathophysiology.

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  • The study aims to develop machine learning models to identify factors linked to Emergence Delirium (ED) in pediatric patients undergoing tonsillectomy or adenotonsillectomy.
  • After cleaning and analyzing a dataset of 423 cases, four predictive models (logistic regression, random forest, support vector machine, and gradient boosting) were tested, with the random forest model showing the best performance (AUC-ROC of 0.96).
  • Key findings highlighted significant correlations between factors like age, weight, and surgery duration with ED risk, while K-means clustering identified distinct patient groups characterized by varying risk levels for ED.
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  • Researchers believe that lung ultrasound scores (LUS) can better predict cardiac risks in elderly patients undergoing hip fracture surgery, compared to existing methods like the Revised Cardiac Risk Index and ASA Physical Status.
  • The study involved 877 patients across 11 Italian hospitals, finding a significant correlation between higher LUS scores and complications, with a notable incidence of major adverse cardiovascular events (MACE).
  • Results showed that a preoperative LUS score of 8 or higher was more effective at predicting MACE than traditional scoring methods, indicating its potential as a valuable tool for risk assessment in this patient population.
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Background: The integration of telemedicine in pain management represents a significant advancement in healthcare delivery, offering opportunities to enhance patient access to specialized care, improve satisfaction, and streamline chronic pain management. Despite its growing adoption, there remains a lack of comprehensive data on its utilization in pain therapy, necessitating a deeper understanding of physicians' perspectives, experiences, and challenges.

Methods: A survey was conducted in Italy between January 2024 and May 2024.

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  • Postoperative pulmonary complications (PPCs) are a significant issue after esophagectomy, affecting up to 40% of patients despite advances in surgical care.
  • This study aims to determine if using high-flow nasal cannula (HFNC) right after extubation can lower PPC rates compared to standard oxygen therapy.
  • The research involves 320 participants who will be randomly assigned to either HFNC or standard therapy post-surgery, with various complications being tracked to assess the effectiveness of each approach.
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  • Lung ultrasonography (LUS) is a useful, non-invasive tool for diagnosing respiratory conditions, particularly in resource-limited settings, as it reduces radiation exposure and quantifies regional loss of aeration.
  • A study assessed the agreement among 20 experienced LUS operators by having them evaluate 25 video clips, revealing strong but not perfect inter-rater reliability, with varying levels of consensus on the scores assigned to the clips.
  • Despite some discrepancies, the findings indicate that LUS scoring can reliably inform severity assessments in respiratory diseases, making it a valuable clinical tool.
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Background: Burnout is a maladaptive response to chronic stress, particularly prevalent among clinicians. Anesthesiologists are at risk of burnout, but the role of maladaptive traits in their vulnerability to burnout remains understudied.

Methods: A secondary analysis was performed on data from the Italian Association of Hospital Anesthesiologists, Pain Medicine Specialists, Critical Care, and Emergency (AAROI-EMAC) physicians.

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Introduction: Cardiac arrest (CA) is the third leading cause of death, with persistently low survival rates despite medical advancements. This article evaluates the potential of emerging technologies to enhance CA management over the next decade, using predictions from the AI tools ChatGPT-4 and Gemini Advanced.

Methods: We conducted an exploratory literature review to envision the future of cardiopulmonary arrest (CA) management.

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  • The use of AI in Clinical Decision Support Systems (CDSS) can really change healthcare and help doctors make better decisions, especially in emergencies.
  • However, creating these AI systems comes with challenges, like making sure they are fair and don’t have biases.
  • To make sure AI is used ethically and effectively, hospitals need to set up special departments that focus on combining human judgment with smart algorithms.
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This systematic review examines the recent use of artificial intelligence, particularly machine learning, in the management of operating rooms. A total of 22 selected studies from February 2019 to September 2023 are analyzed. The review emphasizes the significant impact of AI on predicting surgical case durations, optimizing post-anesthesia care unit resource allocation, and detecting surgical case cancellations.

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Background: Blood pressure has become one of the most important vital signs to monitor in the perioperative setting. Recently, the Italian Society of Anesthesia Analgesia Resuscitation and Intensive Care (SIAARTI) recommended, with low level of evidence, continuous monitoring of blood pressure during the intraoperative period. Continuous monitoring allows for early detection of hypotension, which may potentially lead to a timely treatment.

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Background And Aim: The Nursing undergraduate degree educational program represents an intensive and complex course, and includes a number of professionalizing practical internships, and for these reasons it requires an action to support and improve. Coaching is based on the premise that people have personal strengths and abilities which, through a interview, can be directed to solving their problems. Several studies demonstrate the efficacy of Health Coaching in different University, but never have been measured benefits regard skills improving.

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Background: Four-hundred forty-nine patients affected by Covid-19 were hospitalized at the Rome Military Hospital between March 2020 and July 2022. Depending on the severity of the disease, they were assigned either to the Functional Health Emergency Unit - if suffering from interstitial pneumonia with a clinical manifestation of dyspnea associated with peripheral oxygen saturation  < 92%, and oxygen atmospheric pressure therapy - or to the intensive care unit - if the blood gas-lytic index P/F (ratio between partial pressure of arterial O2 and inspired fraction of O2) was below 150. This prospective observation and monocentric study aim to verify the outcome (healing/death) of early use of remdesivir in pneumonia patients.

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Rationale: Asteoarthritis (OA) is a leading cause of chronic pain in the elderly population and is often associated with emotional comorbidities such as anxiety and depression. Despite age is a risk factor for both OA and mood disorders, preclinical studies are mainly conducted in young adult animals.

Objectives: Here, using young adult (11-week-old) and older adult (20-month-old) mice, we evaluate in a monosodium-iodoacetate-(MIA)-induced OA model the development of anxio-depressive-like behaviors and whether brain neuroinflammation may underlie the observed changes.

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Although proper pain evaluation is mandatory for establishing the appropriate therapy, self-reported pain level assessment has several limitations. Data-driven artificial intelligence (AI) methods can be employed for research on automatic pain assessment (APA). The goal is the development of objective, standardized, and generalizable instruments useful for pain assessment in different clinical contexts.

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