Publications by authors named "Biggs J"

Volcano deformation can be detected over timescales from seconds to decades, offering valuable insights for magma dynamics. However, these signals are shaped by the long-term evolution of magmatic systems, a coupling that remains poorly understood. Here we integrate thermal models of crustal-scale magmatism with thermo-mechanical simulations of ground deformation.

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The purpose of this study was to utilize mixed methods to evaluate the initial implementation of a system of care (SOC) developed and implemented from a community organizing framework. Surveys were conducted with partners (navigators, community partners, parents) to examine changes pre- and post-implementation of the SOC. Surveys assessed care coordination, effectiveness of communication across organizations, quality of services and relationships, barriers, health-related stressors, and distrust.

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Objective: Data comparing the safety profiles of nafcillin and oxacillin are limited in the pediatric patient setting. This study was conducted to compare adverse effect profiles of nafcillin and oxacillin.

Methods: This was a single center retrospective study including patients admitted to a children's hospital who received either nafcillin or oxacillin.

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Introduction: Cluster randomised trials (CRTs) are the gold standard for measuring the community-wide impacts of malaria control tools. CRTs rely on well-defined sample size estimations to detect statistically significant effects of trialled interventions, however these are often predicted poorly by triallists. Here, we review the accuracy of predicted parameters used in sample size calculations for malaria CRTs with epidemiological outcomes.

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Prophylactic drugs against dengue are currently under development. In this study, we explored how such prophylactic approaches might affect dengue cases in four communes of Nha Trang City, Vietnam. A community level dengue transmission survey indicated high levels of previous exposure to dengue (89.

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Article Synopsis
  • Venom systems have evolved multiple times across different plant and animal species and show variation based on factors like evolutionary history and diet.
  • Marine cone snails (genus Conus) are a key model for studying these variations due to their diverse species and significant dietary shifts.
  • Research on the venom genes of 42 cone snail species shows that changes from eating worms to fish lead to unique venom compositions that enhance potency, highlighting how prey choice influences venom characteristics.
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Objective: Despite regulatory challenges, device availability, and rapidly expanding techniques, off-label endovascular repair of complex aortic aneurysms (cAAs) has expanded in the past decade. Given the lack of United States Food and Drug Administration-approved endovascular technology to treat cAAs, we performed a national census to better understand volume and current practice patterns in the United States.

Methods: Targeted sampling identified vascular surgeons with experience in off-label endovascular repair of cAAs.

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In Tanzania, about 600 000 youth between 5 and 24 years old have a disability. Individuals with disabilities face numerous obstacles due to social stigma. The aim of this formative evaluation is to assess how caregivers of children with correctable disabilities (e.

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Background: The need for improved spiritual care education is a national directive, prompting many nursing and medical education programs to respond with spiritual curriculum. This article reports on research that tested an educational intervention to enhance nursing and medical students' understanding of end-of-life communication with families.

Method: This mixed-methods study included three reflection questions to ascertain students' attitudes about their own death and dying.

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Article Synopsis
  • - The study investigates aspirin overdoses in children aged 5 and younger, aiming to link specific doses to medical outcomes, as existing guidelines for referral to emergency care lack sufficient pediatric data.
  • - A review of 26,488 cases showed that most aspirin exposures had no effects, while a small percentage resulted in minor to major effects or death, with lethal doses ranging significantly from 142.2 mg/kg to 284.4 mg/kg.
  • - The findings suggest that the current guideline recommending referral after 150 mg/kg of aspirin ingestion may need re-evaluation, given the observed outcomes and treatment responses in pediatric patients.
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Dengue virus (DENV) causes repeated outbreaks of disease in endemic areas, with patterns of local transmission strongly influenced by seasonality, importation via human movement, immunity, and vector control efforts. An understanding of how each of these interacts to enable endemic transmission (continual circulation of local virus strains) is largely unknown. There are times of the year when no cases are reported, often for extended periods of time, perhaps wrongly implying the successful eradication of a local strain from that area.

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Understanding body malodour in a measurable manner is essential for developing personal care products. Body malodour is the result of bodily secretion of a highly complex mixture of volatile organic compounds. Current body malodour measurement methods are manual, time consuming and costly, requiring an expert panel of assessors to assign a malodour score to each human test subject.

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Background: Spurred by the Coronavirus infectious disease 2019 pandemic, aerosol containment devices (ACDs) were developed to capture infectious respiratory aerosols generated by patients at their source. Prior reviews indicated that such devices had low evidence of effectiveness, but did not address how ACDs should be evaluated, how well they should perform, nor have clearly defined performance standards. Towards developing design criteria for ACDs, two questions were posed: 1) What characteristics have guided the design of ACDs? 2) How have these characteristics been evaluated?

Methods: A scoping review was performed consistent with PRISMA guidelines.

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Traditional education in biological anthropology relies primarily on hands-on, highly visual experiences. Forensic anthropologists, bioarchaeologists, and osteologists in general should aim to collaborate in developing widespread digital pedagogy suitable for our discipline, increasing digital technologies used for education and training. Considerations and suggested pathways toward a biological anthropology digital pedagogy include accommodating for varying levels of digital fluency, understanding global perspectives and cultural beliefs, equity in accessibility, ethical strategies, prioritization levels of content that should be made publicly available, appropriate platforms and forms of media for disseminating different types of content, and the necessity of multiple modalities.

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Unlabelled: Radar (SAR) satellites systematically acquire imagery that can be used for volcano monitoring, characterising magmatic systems and potentially forecasting eruptions on a global scale. However, exploiting the large dataset is limited by the need for manual inspection, meaning timely dissemination of information is challenging. Here we automatically process ~ 600,000 images of > 1000 volcanoes acquired by the Sentinel-1 satellite in a 5-year period (2015-2020) and use the dataset to demonstrate the applicability and limitations of machine learning for detecting deformation signals.

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Monitoring the condition (water quality, biodiversity, hydromorphology) of small water bodies presents a challenge for the relevant authorities in terms of time and resources (labour and financial) due to the extensive length of the stream network or the sheer number of small standing water bodies. Citizen science can help address information gaps, but the effort required should not be underestimated if such projects are to generate reliable and sustained data collection. The overall aim of this paper is to propose a framework for operationalisation of citizen science targeting collection of data from small water bodies.

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(1) Background: Cyanobacteria produce a wide range of secondary metabolites, including tumor-promoting hepatotoxins. We recently reported evidence of an independent association between oral cyanobacteria and hepatocellular carcinoma in a U.S.

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Applications of nitrogen (N) fertiliser to agricultural lands impact many marine and aquatic ecosystems, and improved N fertiliser management is needed to reduce these water quality impacts. Government policies need information on water quality and risk associated with improved practices to evaluate the benefits of their adoption. Policies protecting Great Barrier Reef (GBR) ecosystems are an example of this situation.

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Aseismic afterslip is postseismic fault sliding that may significantly redistribute crustal stresses and drive aftershock sequences. Afterslip is typically modeled through geodetic observations of surface deformation on a case-by-case basis, thus questions of how and why the afterslip moment varies between earthquakes remain largely unaddressed. We compile 148 afterslip studies following 53 6.

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Missed appointments are a problem for health care systems, causing lost revenue and concern for poor health outcomes. This is particularly true at Community Health Centers (CHCs), where clients may already face substantial barriers to optimal care and outcomes. Identified solutions to this problem are limited, and often focus on reminder calls and messages to clients.

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Background: To evaluate outcomes following urgent or emergent fenestrated-branched endovascular aortic repair (F-BEVAR) for pararenal (PRA) and thoracoabdominal aortic aneurysms (TAAA) in patients who are considered high-risk for open repair.

Methods: A retrospective, single institution evaluation of outcomes following F-BEVAR of symptomatic, rapidly enlarging, or ruptured PRA or TAAA treated with physician modified endograft (PMEG) and company manufactured devices (CMD). Outcomes were technical success, 30-day morbidity and mortality, and 1 year aortic related outcomes.

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Article Synopsis
  • The study explores the effectiveness of combining different rapid diagnostic tests (RDTs) to determine dengue virus (DENV) immune status at the point of care, simplifying the diagnostic process.
  • The research involved analyzing serum from dengue patients in Indonesia and Vietnam to correlate rapid test outcomes with laboratory results, revealing a high accuracy in identifying primary and post-primary infections.
  • The findings suggest that using a combination of NS1, IgM, and IgG RDTs can accurately estimate a patient’s DENV immune status, potentially enhancing diagnosis in clinical settings where laboratory access is limited.
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Background: Due to challenges in measuring changes in malaria at low transmission, serology is increasingly being used to complement clinical and parasitological surveillance. Longitudinal studies have shown that serological markers, such as Etramp5.Ag1, can reflect spatio-temporal differences in malaria transmission.

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Persistent global health inequities and workforce shortage require innovative strategies to prepare professionals for teamwork in a global context. Over two years, students (n = 33) from education, nursing, occupational therapy, public health, and physical therapy participated in a course in Zambia that emphasized interprofessional collaborative practice (IPP), cultural fluency, and understanding ecological approaches to health. Faculty measured the learning outcomes of the course using the Interprofessional Education Collaborative (IPEC) Competency Self-Assessment Tool (pre and posttest), and a focus group to gain a deeper understanding of the student experience and course effectiveness.

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Globally, 15,521 animal species are listed as threatened by the International Union for the Conservation of Nature, and of these less than 3% have genomic resources that can inform conservation management. To combat this, global genome initiatives are developing genomic resources, yet production of a reference genome alone does not conserve a species. The reference genome allows us to develop a suite of tools to understand both genome-wide and functional diversity within and between species.

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