Publications by authors named "Bifang Lin"
Abdominal muscles infiltration analgesia for donor-site pain in autologous ear reconstruction: A randomized controlled clinical trial.
J Plast Reconstr Aesthet Surg
December 2024
Article Synopsis
- The study investigates a new pain relief method, RAM+EOM-IA, for patients undergoing autologous ear reconstruction who experience pain at the costal cartilage donor site.
- In a randomized controlled trial, 60 patients were split into two groups: one receiving RAM+EOM-IA combined with intravenous patient-controlled anesthesia (IPCA) and the other receiving IPCA alone, focusing on pain levels and recovery.
- Results showed that RAM+EOM-IA significantly reduced pain scores and the need for rescue medication, while also improving recovery-related mobility without extending sensory block areas beyond the intended regions.
Multiphoton microscopy was used to study the extracellular matrix of keloid at the molecular level without tissue fixation and staining. Direct imaging of collagen and elastin was achieved by second harmonic generation and two-photon excited fluorescence, respectively. The morphology and quantity of collagen and elastin in keloid were characterized and quantitatively analyzed in comparison to normal skin.
View Article and Find Full Text PDFMultiphoton microscopy (MPM) was applied to examine the marginal region at dermis of keloid compared with atrophic scar. High-resolution large-area image showed an obvious boundary at the scar margin and different morphological patterns of elastin and collagen on the two sides, further visualized by the focused three-dimensional images. Content alteration of elastin or collagen between the two sides of boundary was quantified to show significant difference between keloid and atrophic scar.
View Article and Find Full Text PDFScar margins dynamic with time were quantitatively characterized using multiphoton microscopy (MPM). 2D large-area and 3D focused images of elastin and collagen at scar margins were obtained to extract quantitative parameters. An obvious boundary was observed at the scar margin, showing altered morphological patterns of elastin and collagen on both sides.
View Article and Find Full Text PDFThe morphological alterations of human cutaneous normal scar were quantitatively analyzed using multiphoton microscopy (MPM) based on two-photon excited fluorescence and second harmonic generation. High-contrast, high-resolution images of normal scar and uninjured skin were obtained for comparison. In addition, some quantitative parameters have been extracted to quantitatively discriminate between normal scar and uninjured skin.
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