Plasma N-terminal pro-brain natriuretic peptide concentrations may help to identify patients with very low-risk acute pulmonary embolism: A preliminary study.

Background: Patients with an acute pulmonary embolism (APE) are a heterogeneous group, and some of them may benefit from early discharge and an ambulatory care referral. We aimed to evaluate the use of N-terminal pro-brain natriuretic peptide (NT-proBNP) plasma level assessment in patients with low-risk APE based on clinical findings (0 points on the simplified Pulmonary Embolism Severity Index (sPESI)).

Material And Methods: Preliminary analysis of an ongoing prospective study including 1,151 normotensive patients with at least a segmental APE.

Plasma Troponins Identify Patients with Very Low-Risk Acute Pulmonary Embolism.

Introduction: Although in the non-vitamin K oral anticoagulants (NOAC) era majority of low-risk acute pulmonary embolism (APE) patients can be treated at home, identifying those at very low risk of clinical deterioration may be challenging. We aimed to propose the risk stratification algorithm in sPESI 0 point APE patients, allowing them to select candidates for safe outpatient treatment.

Materials And Methods: Post hoc analysis of a prospective study of 1151 normotensive patients with at least segmental APE.

Heart Rate Variability Impairment Is Associated with Right Ventricular Overload and Early Mortality Risk in Patients with Acute Pulmonary Embolism.

The association between heart rate variability (HRV) and mortality risk of acute pulmonary embolism (APE), as well as its association with right ventricular (RV) overload is not well established. We performed an observational study on consecutive patients with confirmed APE. In the first 48 h after admission, 24 h Holter monitoring with assessment of time-domain HRV, echocardiography and NT-proBNP (N-terminal pro-B-type natriuretic peptide) measurement were performed in all participants.

Assessment of the incidence of fragmented QRS in electrocardiography in patients with systemic sclerosis and systemic lupus erythematosus.

Objective: In systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) cardiac involvement is very common, and it might be asymptomatic. We aimed to assess the presence of fragmented QRS (fQRS) - possible indicator of a scar, diffuse damage or conduction system disturbances in those patients.

Methods: We examined 74 patients with SSc, 77 with SLE and 40 healthy controls.

Circuit Quantum Electrodynamics in Hyperbolic Space: From Photon Bound States to Frustrated Spin Models.

Circuit quantum electrodynamics is one of the most promising platforms for efficient quantum simulation and computation. In recent groundbreaking experiments, the immense flexibility of superconducting microwave resonators was utilized to realize hyperbolic lattices that emulate quantum physics in negatively curved space. Here we investigate experimentally feasible settings in which a few superconducting qubits are coupled to a bath of photons evolving on the hyperbolic lattice.

Localization and Criticality in Antiblockaded Two-Dimensional Rydberg Atom Arrays.

Controllable Rydberg atom arrays have provided new insights into fundamental properties of quantum matter both in and out of equilibrium. In this work, we study the effect of experimentally relevant positional disorder on Rydberg atoms trapped in a 2D square lattice under antiblockade (facilitation) conditions. We show that the facilitation conditions lead the connectivity graph of a particular subspace of the full Hilbert space to form a 2D Lieb lattice, which features a singular flat band.

Asymmetric Blockade and Multiqubit Gates via Dipole-Dipole Interactions.

Because of their strong and tunable interactions, Rydberg atoms can be used to realize fast two-qubit entangling gates. We propose a generalization of a generic two-qubit Rydberg-blockade gate to multiqubit Rydberg-blockade gates that involve both many control qubits and many target qubits simultaneously. This is achieved by using strong microwave fields to dress nearby Rydberg states, leading to asymmetric blockade in which control-target interactions are much stronger than control-control and target-target interactions.

, , ACUTE PULMONARY EMBOLISM BY AMNIOTIC FLUID - A RARE COMPLICATION OF PERINATAL PERIOD THAT SHOULD NOT BE FORGOTTEN.

Objective: Amniotic fluid embolism (AFE) is a diagnostically challenging type of pulmonary embolism that occurs when amniotic fluid enters maternal circulation during delivery or postpartum. This obstetric complication is very rare but characterized by high mortality rate. The main symptoms are dyspnea, cardiovascular collapse, disseminated intravascular coagulation (DIC) and even sudden cardiac death.

Serum galectin-3 and galectin-3 binding protein levels in systemic lupus erythematosus and cutaneous lupus erythematosus.

Introduction: The roles of galectin-3 (Gal-3) and galectin-3 binding protein (G3BP) in systemic lupus erythematosus (SLE) are of ongoing interest, but the data are insufficient due to highly limited available studies. There are no data on cutaneous lupus erythematosus (CLE).

Aim: To assess serum Gal-3 and G3BP concentrations in SLE patients with and without LE-specific skin lesions, CLE patients and to correlate levels of proteins with clinical and laboratory parameters.

Quantum simulation of hyperbolic space with circuit quantum electrodynamics: From graphs to geometry.

We show how quantum many-body systems on hyperbolic lattices with nearest-neighbor hopping and local interactions can be mapped onto quantum field theories in continuous negatively curved space. The underlying lattices have recently been realized experimentally with superconducting resonators and therefore allow for a table-top quantum simulation of quantum physics in curved background. Our mapping provides a computational tool to determine observables of the discrete system even for large lattices, where exact diagonalization fails.

Holter-Derived Autonomic Function, Arrhythmias and Carbohydrate Metabolism in Patients with Class III Obesity Treated with Laparoscopic Sleeve Gastrectomy.

The effects of weight loss following bariatric surgery on autonomic balance, arrhythmias and insulin resistance are still of interest. We prospectively investigated 50 patients with BMI > 40 kg/m, aged 36.5 (18-56) years who underwent laparoscopic sleeve gastrectomy.

Tunable Three-Body Loss in a Nonlinear Rydberg Medium.

Long-range Rydberg interactions, in combination with electromagnetically induced transparency (EIT), give rise to strongly interacting photons where the strength, sign, and form of the interactions are widely tunable and controllable. Such control can be applied to both coherent and dissipative interactions, which provides the potential for generating novel few-photon states. Recently it has been shown that Rydberg-EIT is a rare system in which three-body interactions can be as strong or stronger than two-body interactions.

Left ventricular diastolic dysfunction and diseases severity contribute to impaired exercise capacity in systemic lupus erythematosus.

Objectives: Patients with systemic lupus erythematosus (SLE) have a higher risk of myocardial involvement, which can result in ventricular dysfunction. The aim of our study was to estimate potential relationship between exercise capacity assessed by six minute walk test (6MWT) and echocardiographic parameters of left and right ventricular function in SLE patients.

Methods: We prospectively studied 66 SLE patients (57 F, age 44 (20-75) years) and 27 age matched healthy subjects.

Quench Dynamics of a Fermi Gas with Strong Nonlocal Interactions.

We induce strong nonlocal interactions in a 2D Fermi gas in an optical lattice using Rydberg dressing. The system is approximately described by a model on a square lattice where the fermions experience isotropic nearest-neighbor interactions and are free to hop only along one direction. We measure the interactions using many-body Ramsey interferometry and study the lifetime of the gas in the presence of tunneling, finding that tunneling does not reduce the lifetime.

Optimal measurement of field properties with quantum sensor networks.

We consider a quantum sensor network of qubit sensors coupled to a field ( ; ) analytically parameterized by the vector of parameters . The qubit sensors are fixed at positions , …, . While the functional form of ( ; ) is known, the parameters are not.

Comprehensive non-invasive assessment of electrocardiographic abnormalities and cardiac arrhythmias in patients with genetically confirmed mitochondrial diseases.

Background: There is limited data on cardiac arrhythmias and ventricular repolarization and dispersion abnormalities in patients with mitochondrial diseases (MitD).

Methods: Consecutive 40 patients with genetically proven MitD and 35 healthy controls were studied. Among other examinations all subjects underwent 24-h Holter recording and 12‑lead electrocardiography (ECG) with corrected QT (QTc), QT dispersion (QTd), Tp-e and Tp-e/QT ratio assessment.

Photon propagation through dissipative Rydberg media at large input rates.

We study the dissipative propagation of quantized light in interacting Rydberg media under the conditions of electromagnetically induced transparency. Rydberg blockade physics in optically dense atomic media leads to strong dissipative interactions between single photons. The regime of high incoming photon flux constitutes a challenging many-body dissipative problem.

Coherent optical nanotweezers for ultracold atoms.

There has been a recent surge of interest and progress in creating subwavelength free-space optical potentials for ultracold atoms. A key open question is whether geometric potentials, which are repulsive and ubiquitous in the creation of subwavelength free-space potentials, forbid the creation of narrow traps with long lifetimes. Here, we show that it is possible to create such traps.

Assessment of arrhythmias and cardiac autonomic tone at a relatively young age patients with obesity class III.

There is no sufficient data on arrhythmias occurrence in obesity class III. The influence of hyperinsulinemia and insulin resistance on arrhythmias and cardiac autonomic tone is also of ongoing interest in these subjects. We prospectively studied 81 selected patients with body mass index >40 kg/m , aged 34 (18-65) years.

Minimal Model for Fast Scrambling.

We study quantum information scrambling in spin models with both long-range all-to-all and short-range interactions. We argue that a simple global, spatially homogeneous interaction together with local chaotic dynamics is sufficient to give rise to fast scrambling, which describes the spread of quantum information over the entire system in a time that is logarithmic in the system size. This is illustrated in two tractable models: (1) a random circuit with Haar random local unitaries and a global interaction and (2) a classical model of globally coupled nonlinear oscillators.

Exotic Photonic Molecules via Lennard-Jones-like Potentials.

Ultracold systems offer an unprecedented level of control of interactions between atoms. An important challenge is to achieve a similar level of control of the interactions between photons. Towards this goal, we propose a realization of a novel Lennard-Jones-like potential between photons coupled to the Rydberg states via electromagnetically induced transparency (EIT).

Nondestructive Cooling of an Atomic Quantum Register via State-Insensitive Rydberg Interactions.

We propose a protocol for sympathetically cooling neutral atoms without destroying the quantum information stored in their internal states. This is achieved by designing state-insensitive Rydberg interactions between the data-carrying atoms and cold auxiliary atoms. The resulting interactions give rise to an effective phonon coupling, which leads to the transfer of heat from the data atoms to the auxiliary atoms, where the latter can be cooled by conventional methods.

Floquet engineering of optical lattices with spatial features and periodicity below the diffraction limit.

Floquet engineering or coherent time periodic driving of quantum systems has been successfully used to synthesize Hamiltonians with novel properties. In ultracold atomic systems, this has led to experimental realizations of artificial gauge fields, topological band structures, and observation of dynamical localization, to name just a few. Here we present a Floquet-based framework to stroboscopically engineer Hamiltonians with spatial features and periodicity below the diffraction limit of light used to create them, by time-averaging over various configurations of a 1D optical Kronig-Penney (KP) lattice.