Objective: The usefulness of the rapid-induction techniques of hypnosis as an adjunctive weight-loss treatment has not been defined. This randomized controlled trial evaluated whether self-conditioning techniques (self-hypnosis) added to lifestyle interventions contributed to weight loss (primary outcome), changes in metabolic and inflammatory variables, and quality of life (QoL) improvement (secondary outcomes) in severe obesity.
Methods: Individuals (with BMI = 35-50 kg/m ) without organic or psychiatric comorbidity were randomly assigned to the intervention (n = 60) or control arm (n = 60).