Prevalence and genotypes distribution of virus hepatitis B and hepatitis delta virus in chronic liver diseases in Kazakhstan.

Background: The geographical distribution of hepatitis B virus (HBV) and hepatitis D virus (HDV) genotypes is uneven and has its own clinical and organizational implications for health systems. Despite the introduction of vaccination and successful antiviral therapy the prevalence of chronic hepatitis B (with or without delta agent) increased over the past 5 years. This study aimed for the first time to investigate the molecular epidemiology of HBV and HDV in Kazakhstan.

Evolution of Liver Transplantation in Kazakhstan: Two-Era Experience of a Single Center, the First Report.

Background: Liver transplantation has been performed in Kazakhstan since 2011. The present study aimed to analyze the outcomes of the most experienced liver transplant center in Kazakhstan.

Methods: Between December 2011 and December 2018, 131 liver transplantations were performed at A.

Clinical and Morphologic Diagnostic Assessments of Liver Diseases After Liver Transplant.

Objectives: At the National Scientific Center of Surgery named A. Syzganova, more than 100 liver transplants have been conducted from 2012 to November 2017. Survival and quality of life of patients in the posttransplant period largely depend on the compliance of patients, monitoring of complications, cause of liver disease, the severity of the condition of patients in the pretransplant period, and the technical features of the operation.

Serum BAFF and APRIL levels in patients with PBC.

B-cell-activating factor belonging to the TNF family (BAFF) and a proliferation-inducing ligand (APRIL) are known to be involved in the occurrence of autoimmune diseases. We assessed serum levels of these cytokines in PBC patients. Serum BAFF levels were significantly higher in PBC patients than in healthy controls (1253.