Malignant hyperthermia syndrome: A rare entity.

Background: Malignant hyperthermia syndrome is a hereditary pharmacogenetic disorder of skeletal muscle characterized by hypermetabolic state related to the exposure of volatile anesthetic gases or depolarizing muscle relaxants. It is an infrequent entity that occurs in genetically predisposed individuals, with a very low incidence in pediatrics (1 in 10,000-15,000 anesthetic procedures).

Case Report: We report a case of malignant hyperthermia related to exposure to sevoflurane during adenoidectomy surgery in a 6-year-old female.

Assessment of proadrenomedullin as diagnostic or prognostic biomarker of acute appendicitis in children with acute abdominal pain.

Background: Acute appendicitis (AA) is one of the most frequent surgical pathologies in pediatrics.

Objectives: To investigate the utility of proadrenomedullin (pro-ADM) for the diagnosis of AA.

Methods: Prospective, analytical, observational, and multicenter study conducted in 6 pediatric emergency departments.