Correction: Quinacrine inhibits GSTA1 activity and induces apoptosis through G/S arrest and generation of ROS in human non-small cell lung cancer cell lines.

[This corrects the article DOI: 10.18632/oncotarget.27558.

Quinacrine inhibits GSTA1 activity and induces apoptosis through G/S arrest and generation of ROS in human non-small cell lung cancer cell lines.

Background: Quinacrine (QC) is popular for its anti-malarial activity. It has been reported exhibiting anti-cancerous properties by suppressing nuclear factor-κB and activating p53 signaling; however, its effect on cellular pathways in human non-small cell lung cancer (NSCLC) has not been studied.

Materials And Methods: Binding of QC with GSTA1 was studied computationally as well as through GST activity assay kit.

A novel molecular mechanism for a long non-coding RNA PCAT92 implicated in prostate cancer.

The role of many lncRNAs in cancer remains elusive including that for a Prostate Cancer Associated Transcript 92 (PCAT92). PCAT92 shares the locus on chromosome 13 with ABCC4 gene, known to be implicated in prostate cancer. It has been shown that PCAT92 and ABCC4 are up-regulated in prostate cancer samples from multiple transcriptome datasets.

Integrative Analysis of Normal Long Intergenic Non-Coding RNAs in Prostate Cancer.

Recently, large numbers of normal human tissues have been profiled for non-coding RNAs and more than fourteen thousand long intergenic non-coding RNAs (lincRNAs) are found expressed in normal human tissues. The functional roles of these normal lincRNAs (nlincRNAs) in the regulation of protein coding genes in normal and disease biology are yet to be established. Here, we have profiled two RNA-seq datasets including cancer and matched non-neoplastic tissues from 12 individuals from diverse demography for both coding genes and nlincRNAs.