We investigated coupled-qubit-based thermal machines powered by quantum measurements and feedback. We considered two different versions of the machine: (1) a quantum Maxwell's demon, where the coupled-qubit system is connected to a detachable single shared bath, and (2) a measurement-assisted refrigerator, where the coupled-qubit system is in contact with a hot and cold bath. In the quantum Maxwell's demon case, we discuss both discrete and continuous measurements.
View Article and Find Full Text PDFJ Nepal Health Res Counc
November 2022
Background: Pre-operative anxiety is unpleasant state of tension or uneasiness that results from patient doubt and fear before an operation. This study aims at assessing level of state and trait anxiety and other associated factors among preoperative patient.
Methods: A descriptive cross-sectional study was done among 195 patients above 18 years of age planned for elective surgery the following day in different departments in tertiary care center.
Introduction: The post-coronavirus disease 2019 (COVID-19) syndrome is defined as the persistence of symptoms after viral clearance and the emergence of new symptoms after a few months following recovery from COVID-19. This study aimed to assess the prevalence of post-COVID-19 syndrome and the risk factors that contribute to its development.
Methods: This study was conducted prospectively in Tribhuvan University Teaching Hospital (TUTH), located in Maharajgunj, Kathmandu.
Dravet syndrome is rare genetic epilepsy syndrome and epileptic encephalopathy. The patient initially has normal developmental profile with plateau or regression that begins after seizure onset. We report a case of two-year-old child diagnosed as dravet syndrome with moderate cerebral atrophy and ventricular dilatation as rare MRI finding.
View Article and Find Full Text PDFJ Nepal Health Res Counc
December 2021
Background: Pandemic of COVID-19 has engulfed Nepal as well. In this paper, we studied the demographic, clinical, laboratory findings as well as the treatment modalities, prognostic factors and outcome of patients admitted with COVID-19.
Methods: This was an observational cross-sectional study that included all patients admitted to the General Medicine Department of College of Medical Sciences, Bharatpur, during the first wave of COVID-19 from April 2020 to February 2021 after obtaining the ethical clearance.
Introduction: Scrub typhus is a mite borne infectious disease caused by Orientia tsutsugamushi, obligate intracellular bacteria, transmitted by chigger mites. Scrub typhus is an emerging febrile illness with clinical suspicion being the only key to diagnosis. This study was conducted to find out the prevalence of Scrub typhus among febrile children in a tertiary care center of central Nepal.
View Article and Find Full Text PDFPharmacogenomics (PGx) is increasingly being recognized as a potential tool for improving the efficacy and safety of drug therapy. Therefore, several efforts have been undertaken globally to facilitate the implementation process of PGx into routine clinical practice. Part of these efforts include the formation of PGx working groups working on PGx research, synthesis, and dissemination of PGx data and creation of PGx implementation strategies.
View Article and Find Full Text PDFWe experimentally realize protocols that allow us to extract work beyond the free energy difference from a single-electron transistor at the single thermodynamic trajectory level. With two carefully designed out-of-equilibrium driving cycles featuring kicks of the control parameter, we demonstrate work extraction up to large fractions of k_{B}T or with probabilities substantially greater than 1/2, despite the zero free energy difference over the cycle. Our results are explained in the framework of nonequilibrium fluctuation relations.
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