Publications by authors named "Bianca R Acacio"
Article Synopsis
- The kernel oil from Attalea phalerata, or Acurí, has traditional uses in treating respiratory issues, inflammation, and fever, but lacks pharmaceutical research.
- A study developed Acurí oil-loaded nanocapsules, assessing their cytotoxicity, anti-inflammatory effects, and oral toxicity in rats, showing promising results such as high encapsulation efficiency and stability.
- The nanocapsules provided significant anti-inflammatory and antiproliferative effects against cancer cells while being nontoxic, indicating potential for new antitumor therapies and nutraceutical applications.
The objective of this study was to reduce the effects of cryoinjury caused in bovine semen by cryopreservation. Ejaculates were collected from Nellore bulls and subjected to freezing in C (control), ozone (15, 30, and 60 µg mL of ozone), quercetin (25, 50, and 100 µg mL of quercetin), and carnosine groups (100, 200, and 300 ng mL of carnosine). Samples were evaluated post-thaw (M0) and post-rapid thermoresistance test (M30) for sperm kinetics (total motility, progressive motility, curvilinear speed, linearity and amplitude of lateral head displacement) and cell structure viability (plasma membrane integrity, acrosomal integrity, mitochondrial potential, membrane fluidity, and lipid peroxidation).
View Article and Find Full Text PDFThe objective of the experiment was to evaluate the effect of the addition of different concentrations of the antioxidants Coenzyme Q10 (CoQ10) and melatonin to equine semen freezing diluent, alone or in combination, during the cryopreservation process. Twenty ejaculates (n = 5 stallions) were divided in groups: Control (C, without the addition of antioxidants), melatonin 0.75 mM (MEL1), melatonin 1.
View Article and Find Full Text PDFThe aim of this study was to determine an ozone dosage capable of inducing pro-oxidation, and to verify its action on sperm cells during the process of cooling and cryopreservation of equine semen. In this study, we evaluated the ozone concentrations of 2µg/mL,15µg/mL, 30µg/mL e 60 µg/mL added in equine semen cooling and freezing extenders. Samples were evaluated for sperm kinetics patterns, function of sperm structures and lipid peroxidation.
View Article and Find Full Text PDFObjective: To evaluate the training and standardization methods of multiple simulated patients (SPs) performing a single scenario in a multicenter study.
Methods: A prospective quasi-experimental study, using a multicenter approach, evaluated the performance of five different individuals with the same biotype during a simulation session in a high-fidelity environment. The SPs training and standardization process consisted of four steps and six web or face-to-face mediated: Step 1: simulation scenario design and pilot test.