Publications by authors named "Bianca Nichele Kusma"

Article Synopsis
  • - Chronic myeloid leukemia (CML) is characterized by a specific genetic translocation (BCR::ABL1) that serves as a primary biomarker for diagnosis and prognosis, but research is exploring additional potential biomarkers like long noncoding RNAs (lncRNAs) and mRNAs.
  • - A study utilizing RNA sequencing compared gene expression in 6 CML patients with high expression levels to 6 healthy individuals, followed by validation using RT-qPCR on samples from 87 CML patients and 42 healthy controls.
  • - The findings indicated lower expression levels of certain genes in CML patients, and a relationship was observed where higher levels of one gene are linked to reduced expression of another in the context of treatment with imatin
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