Publications by authors named "Bianca Mannig"
Immune signatures of prodromal multiple sclerosis in monozygotic twins.
Proc Natl Acad Sci U S A
September 2020
Article Synopsis
- Researchers studied 43 pairs of monozygotic twins, one with multiple sclerosis (MS) and the other healthy, to better understand immune differences related to MS.
- They found that the immune signatures of both twins were mostly similar, with twinship contributing 56% to immune variation, while MS itself contributed only 1-2%.
- Notably, distinct immune traits in CD4 effector T cells were identified in a subgroup, suggesting that T cells play a crucial role in the early stages of MS development.