Factors for pain in patients with different grades of knee osteoarthritis.

Objective: Discordance between having pain and radiologic osteoarthritis (OA) is a well-established fact. It is suggested that this particularly applies to the less severe grades of OA. However, some people with a Kellgren/Lawrence (K/L) grade of 3 or 4 for OA are without pain.

No clear association between female hormonal aspects and osteoarthritis of the hand, hip and knee: a systematic review.

Objective: Incidence of OA rises steeply in women of age >50 years; the climacteric period for women. The simultaneous occurrence of these events suggests an association between OA and changes in female hormonal aspects. This systematic review studies the assumed association between OA and aspects concerning the fertile period (duration, endogenous hormones, age at menarche/menopause) and the menopause [menopausal status, years since menopause (YSM) and surgical menopause].

Good reliability, questionable validity of 25 different classification criteria of knee osteoarthritis: a systematic appraisal.

Objectives: Despite extensive epidemiological and clinical research, there is no consensus on classification criteria to define knee osteoarthritis (OA). No gold standard is available and many different definitions are used. For future research and interpretation of epidemiological studies, we aimed to evaluate reliability and validity of commonly used classification criteria.