Survival and Surgical Complications in Anaplastic Thyroid Cancer Patients After Completed Multimodal Treatment.

Background/aim: This study aimed to examine survival and surgical complications in patients with anaplastic thyroid cancer (ATC) after multimodal treatment.

Patients And Methods: Since 2002, the recommended treatment strategy for ATC at our centre has been hyperfractionated accelerated radiotherapy (HART) with high doses to the neck (64 Gy), combined with weekly doxorubicin, and surgery after 4-8 weeks, if feasible.

Results: Between 2002 and 2014, 14 patients completed HART and thyroid surgery.

From the clavicle to the windpipe: Tracheal window resections reconstructed with calcifying periosteum in thyroid cancer.

Objectives: We aimed to evaluate the outcomes of tracheal window resection and reconstruction using a vascularized periosteal flap (intended for calcification) harvested from the medial clavicle. This is one of several surgical techniques for tracheal resection and reconstruction used for patients with thyroid carcinoma invading the trachea. Importantly, in partial tracheal resection postoperative dynamic airway collapse must be prevented.

Anaplastic thyroid cancer and hyperfractionated accelerated radiotherapy (HART) with and without surgery.

Anaplastic carcinoma of the thyroid gland (ATC) is one of the most aggressive cancers in humans. With insufficient treatment, the disease most often leads to death in suffocation. From 2002, our treatment strategy has been hyperfractionated accelerated radiotherapy (HART) with high doses (64 Gy) to the neck, followed by surgery 4-8 weeks later if feasible, with the aim to gain control in the neck.

Users' and GPs' causal attributions of illegal substance use: an exploratory interview study.

Objective: There is a need to explore the beliefs regarding the causes of illegal substance use of the people who themselves use the substances (SU) and their GPs. Increased knowledge about such beliefs--often referred to as causal attributions--may improve mutual understanding and communication between SU and GPs.

Methods: Eight SU and five GPs were interviewed about the causes of illegal substance use.