Publications by authors named "Bianca Kruger"
Article Synopsis
- * The drug's effectiveness is influenced by various genetic factors and its metabolism by specific enzymes, which differ among populations worldwide.
- * There is a notable lack of pharmacogenetic research on tamoxifen in African populations, emphasizing the need for targeted studies to enhance treatment outcomes and reduce side effects for African breast cancer patients.
Pharmacogenomics is universally relevant for worldwide modern therapeutics and yet needs further development in resource-limited countries. While there is an abundance of genetic association studies in controlled medical settings, there is a paucity of studies with a naturalistic design in real-life clinical practice in patients with comorbidities and under multiple drug treatment regimens. African patients are often burdened with communicable and noncommunicable comorbidities, yet the application of pharmacogenomics in African clinical settings remains limited.
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