Cancer Epidemiol Biomarkers Prev
December 2021
A closed gas loop bioprocess was developed to improve fungal biotransformation of monoterpenes. By circulating monoterpene-saturated process gas, the evaporative loss of the volatile precursor from the medium during the biotransformation was avoided. Penicillium solitum, isolated from kiwi, turned out to be highly tolerant towards monoterpenes and to convert alpha-pinene to a range of products including verbenone, a valuable aroma compound.
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