Publications by authors named "Bian-Qin Guo"
Application of Tivantinib for Hepatocellular Carcinoma: A Meta-Analysis Study.
Evid Based Complement Alternat Med
June 2022
Article Synopsis
- The study investigates the effectiveness of tivantinib compared to a placebo in treating MET-high hepatocellular carcinoma.
- Researchers conducted a systematic review of multiple databases up to March 2022, focusing on randomized controlled trials (RCTs) involving tivantinib.
- The results indicate that tivantinib does not significantly improve overall survival or other key outcomes compared to placebo, but it does increase the risk of severe neutropenia.
Article Synopsis
- The study explores the innovative use of aerated fermentation, combining two microorganisms, Bacillus subtilis and Trichoderma reesei, to improve ginsenoside production from white ginseng roots.
- It identifies corn steep liquor as the best nitrogen source, with optimal conditions including 15 g/L of ginseng powder and a 1:4 ratio of the two microorganisms, resulting in a total ginsenoside yield of 21.79%.
- The findings suggest that using staged inoculation in co-cultivation boosts ginsenoside transformation and enhances the pharmacological properties of the fermented solution.
Objective: To explore the clinical value of serum IgM and IgG to SARS-CoV-2 in COVID-19.
Methods: 105 COVID-19 patients were enrolled as the disease group. 197 non-COVID-19 patients served as the control group.
[Value of Serum Light Chain in Diagnosis and Evaluation of Efficacy for Multiple Myeloma].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2020
Article Synopsis
- The study investigates the usefulness of serum light chain (sLC) levels in diagnosing multiple myeloma and evaluating treatment effectiveness.
- It involved 46 newly diagnosed multiple myeloma patients and 50 healthy controls, using various laboratory techniques to compare the sensitivity and specificity of sLC with standard tests.
- Results indicate that sLC detection is beneficial for early diagnosis and can track disease progression and treatment response in multiple myeloma patients.
[Prokaryotic expression and purification of a tandem repeat of ovarian cancer antigen CA125 and preparation of its antiserum].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
November 2012
Article Synopsis
- The aim of the study was to create a prokaryotic expression system for the CA125 tandem repeat protein (CA125R), purify the protein, and develop an antiserum against it.
- Researchers synthesized the CA125 gene, cloned it into a vector, transformed it into E.coli, optimized expression conditions, and used chromatography and Western blotting to purify and confirm the protein.
- The study successfully produced a high-purity CA125R protein and generated specific antiserum that recognizes both the recombinant and natural forms of the CA125 glycoprotein.