Publications by authors named "Bi-Ying Liu"
Article Synopsis
- Many existing bioinspired osmotic energy systems using selective membranes are not truly effective compared to biological models, particularly in generating power with specific ionic channels.
- Researchers developed a K-channel using a special K-selective ligand and graphene oxide membrane, achieving a high selectivity ratio for potassium over sodium.
- The newly constructed K-selective iso-osmotic power generator (KSIPG) demonstrated a power density of about 15.1 mW/m, outperforming traditional methods and suggesting potential applications in various fields like self-powered systems and medical technology.
Background: Aberrant activation of Wnt/β-catenin signaling by dysregulated post-translational protein modifications, especially ubiquitination is causally linked to cancer development and progression. Although Lys48-linked ubiquitination is known to regulate Wnt/β-catenin signaling, it remains largely obscure how other types of ubiquitination, such as linear ubiquitination governs its signaling activity.
Methods: The expression and regulatory mechanism of linear ubiquitin chain assembly complex (LUBAC) on Wnt/β-catenin signaling was examined by immunoprecipitation, western blot and immunohistochemical staining.