Publications by authors named "Bi-Tian Zhang"

Identification of bioactive components is an important area of research in traditional Chinese medicine (TCM) formula. The reported identification methods only consider the interaction between the components and the target proteins, which is not sufficient to explain the influence of TCM on the gene expression. Here, we propose the Initial Transcription Process-based Identification (ITPI) method for the discovery of bioactive components that influence transcription factors (TFs).

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Article Synopsis
  • * After administering TZS, researchers analyzed absorbed components and predicted their chemical structures, identifying five key compounds including parishin B and C, which could be linked to TZS's effects.
  • * The findings suggest potential mechanisms of TZS in treating VD through various biochemical pathways, highlighting the use of modern technologies to enhance the understanding and effectiveness of traditional herbal medicines.
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