Clinical manifestations and MRI features of vaginal endodermal sinus tumors in four children.

Background: Vaginal endodermal sinus tumor is a rare entity.

Objective: The purpose of this study was to report the clinical manifestations and MRI features in a case series.

Materials And Methods: Children with vaginal endodermal sinus tumor admitted to our hospitals between January 2008 and August 2012 were included.

MRI manifestations of adult choledochal cysts associated with biliary malignancy: a report of ten cases.

Background: To retrospectively review the MRI imaging features of adult choledochal cysts associated with biliary malignancy.

Patients And Methods: Ten out of 72 cases of adult choledochal cysts were found to be associated with biliary malignancy between January 1, 2003 and April 1, 2011 in our hospital database. The following MRI findings of these ten patients were retrospectively reviewed: the type of choledochal cysts, the presence of anomalous union of the pancreaticobiliary duct (AUPBD), manifestations of biliary malignancy, and concomitant findings.

Synergistic anticancer effect of rAd/P53 combined with 5-fluorouracil or iodized oil in the early therapeutic response of human colon cancer in vivo.

Exogenous wild-type p53 (wt-p53) tumor suppression increases the sensitivity of tumor cells to radiotherapy and chemotherapy. An iodized oil emulsion was used as a p53 vector for intra-arterial gene delivery to treat hepatic tumors. Whether the chemotherapeutic agent or the iodized oil affects exogenous wt-p53 activity remains poorly understood.

Optimal technique of three-dimensional MRI of the lumbar nerve root and its radicular vein in normal and lumbar disc herniation patients.

Background: Although three-dimensional MRI (3D-MRI) of short T1 inversion recovery turbo spin-echo (STIR TSE) has showed superior to two-dimensional MRI (2D-MRI) in showing the spinal cord and lumbar nerve roots, it remains difficult in demonstrating radicular vein at present. We have found that short T1 inversion recovery long time echo (STIR LONG TE) was better in showing radicular vein. To further study the methods and character of the 3D-MRI of lumbar nerve root, ganglions and radicular vein in normal and lumbar disc herniation (LDH) adults, in the present study, we evaluated two 3D-MRI techniques, STIR TSE and STIR LONG TE for demonstrating lumbar nerve roots and especial radicular vein in normal and LDH adults.

Hepatocellular carcinoma with bile duct tumor thrombus: dynamic computed tomography findings and histopathologic correlation.

Purpose: This purpose of this study was to analyze the computed tomography (CT) findings of hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT) and explore their correlations with pathological manifestations.

Methods: The clinical data, CT findings, and pathological manifestations of the 16 HCC patients with BDTT were retrospectively reviewed. All cases were pathologically proven.

Juxta-adrenal schwannoma: dynamic multi-slice CT and MRI findings.

Background: We retrospectively analyzed the MSCT and MRI findings of three cases of juxta-adrenal schwannoma and reviewed literature.

Methods And Results: Three patients were male, and showed no signs for endocrine activity. The three cases of juxta-adrenal schwannoma were all well-circumscribed, oval masses with cystic components, and one case with hemorrhage.

In vivo MR imaging tracking of transplanted mesenchymal stem cells in a rabbit model of acute peripheral nerve traction injury.

Purpose: To investigate in vivo MRI tracking mesenchymal stem cells (MSCs) in peripheral nerve injures using a clinically available paramagnetic contrast agent (Gd-DTPA) and commercially available rhodamine-incorporated transfection reagents (PEI-FluoR).

Materials And Methods: After bone marrow MSCs were labeled with Gd-DTPA and PEI-FluoR complex, the labeling efficacy and longevity of Gd-DTPA maintenance were measured and cell viability, proliferation, and apoptosis were assessed. Thirty-six rabbits with acute sciatic nerve traction injury randomly received 1 × 10(6) labeled (n = 12) or unlabeled MSCs (n = 12) or vehicle alone injection.

[Value of magnetic resonance imaging in displaying the parotid gland segments of the facial nerve].

Objective: To evaluate the value of magnetic resonance imaging (MRI) in displaying the parotid gland segments of the facial nerve.

Methods: Sixteen volunteers (9 males and 7 females) and 132 surgically confirmed patients with parotid tumors locating in the deep or shallow lobe of the parotid gland (including 89 with benign and 43 with malignant tumors) underwent MRI using T1WI and T2WI. The transverse images were obtained with the plane tilted 35 degrees to the foot, and the coronal images were acquired using conventional scanning.

Intraspinal primitive neuroectodermal tumor: imaging findings in six cases.

Purpose: To retrospectively review CT and MRI findings in a series of six intraspinal primitive neuroectoderal tumors and to find out their radiological features.

Methods: CT and MRI of six patients with surgically and pathologically proved intraspinal primitive neuroectoderal tumor were retrospectively reviewed. The tumor location, morphological features, signal intensity, calcification, contrast enhancement characteristics, involvement of paraspinal soft tissues and adjacent bony structures were assessed.

[Magnetic resonance imaging for diagnosis of parotid malignant tumors and the pathological basis].

Objective: To investigate magnetic resonance imaging (MRI) features of parotid malignant tumors and study their pathological basis.

Methods: Forty-seven patients with parotid malignant tumors confirmed by surgery (41 patients) or biopsy (6 patients) were enrolled in this study. A comparative analysis was conducted of the pathological and MRI findings in 30 patients with the entire lesions available.

MR neurography: T1 and T2 measurements in acute peripheral nerve traction injury in rabbits.

Purpose: To prospectively evaluate magnetic resonance (MR) signal abnormalities and the time course of T1 and T2 values in a rabbit model of acute nerve traction injury with histologic and functional recovery correlation.

Materials And Methods: All experimental protocols were approved by the institutional animal use and care committee. Acute traction injury was produced in the sciatic nerve of one hind limb in each of 28 rabbits.

Small hepatocellular carcinoma with bile duct tumor thrombi: CT and MRI findings.

Background: Small hepatocellular carcinoma (sHCC) with bile duct tumor thrombi (BDTT) is rare and easily misdiagnosed as cholangiocarcinoma. This study was to analyze the imaging features of sHCC with BDTT.

Patients And Methods: CT and/or MRI examinations were performed on seven patients who had sHCC with BDTT.

[Value of Radiation Therapy Oncology Group guidelines based on MR imaging in diagnosing lymph node metastasis of nasopharyngeal carcinoma].

Background And Objective: Radiation Therapy Oncology Group (RTOG) and other major cooperative groups endorse the consensus guidelines for the delineation of the node levels in stage N0 cases. But it is unclear if these guidelines can be extrapolated to N+ cases. This study was to explore the value of RTOG guidelines in delineating cervical target volumes for nasopharyngeal carcinoma (NPC) patients with lymph node metastasis.

[Adenovirus mediated gene transfer of tyrosinase gene on HepG2 cell by magnetic resonance imaging].

Objective: To evaluate the transfect results of recombinant adenovirus vector carrying tyrosinase gene (Ad-tyr) in vitro by magnetic resonance imaging (MRI) after the Ad-tyr was transfected into HepG2 cell.

Methods: The Ad-tyr which carried the full-length cDNA of tyrosinase gene was transfected into HepG2 cell. The transfected cells were scan by MRI sequences of T1 weighted image (T1WI) , T2 weighted image (T2WI) , and short time inversion recovery (STIR) to observe the MRI signals of expressed melanin.

[Imaging manifestations and pathologic features of soft tissue desmoid-type fibromatosis].

Background & Objective: Soft tissue desmoid-type fibromatosis is a type of benign, infiltrative tumors which are rarely seen. This study was to analyze CT and MR manifestations and pathologic features of soft tissue desmoid-type fibromatosis to improve its diagnostic accuracy.

Methods: A total of 34 soft tissue desmoid-type fibromatosis from 29 patients, including 20 primary and 14 recurrent tumors were analyzed.

[Dynamic contrast-enhanced MR imaging and digital subtraction angiography manifestation of hepatic focal nodular hyperplasia].

Background & Objective: Focal nodular hyperplasia (FNH) is a rare benign hepatic tumor and its imaging diagnosis remains difficult. This study was to analyze dynamic contrast-enhanced MR imaging and digital subtraction angiography (DSA) manifestation of FNH, and to improve the diagnostic accuracy of FNH.

Methods: The MRI and DSA imaging data of 30 patients with FNH proved by pathology were reviewed.

Semi-quantitating stiffness of breast solid lesions in ultrasonic elastography.

Rationale And Objectives: To explore whether strain ratio measurement could semi-quantitatively evaluate the stiffness of breast lesions.

Materials And Methods: From January 2008 to May 2008, 148 patients with 254 solid lesions (183 benign, 71 malignant) in the breast were included in the study. Ultrasound sonography found the lesions and ultrasonic elastography obtained the strain images.

[Value of multi-slice spiral CT with three-dimensional reconstruction in the diagnosis of neoplastic lesions in the jawbones].

Objective: To assess the value of multi-slice spiral CT (MSCT) with three dimensional (3D) reconstruction in the diagnosis of neoplastic lesions in the jawbones.

Methods: Thirty-three patients with neoplastic lesions of the jawbones underwent MSCT scanning with 3D reconstruction. Of these patients, 14 had ameloblastoma, 8 had hemangioma, 3 had osteosarcoma, 3 had ossifying fibroma, 2 had chondrosarcoma, 2 had fibrosarcoma, and 1 had odontogenic myxoma.

[Correlation of MRI features to histopathologic grade of soft tissue sarcoma].

Background & Objective: Peripheral tumor growth pattern plays an important role in the local recurrence and metastases of soft tissue sarcoma. This study was to determine the peripheral growth pattern of soft tissue sarcoma by magnetic resonance imaging (MRI), explore its correlation to histological grade, and assess biological features of soft tissue sarcoma before operation.

Methods: MRI was performed in 59 patients with soft tissue sarcoma.

Bone marrow MR imaging as predictors of outcome in hemopoietic stem cell transplantation.

The purpose of this study is to investigate the role of femoral marrow MR imaging as predictor of outcome for hemopoietic stem cell transplantation (HSCT) in beta-thalassemia major. MR imaging of the proximal femur, including T1- and T2-weighted spin echo and short-tau inversion recovery and in-phase and out-of-phase fast field echo images, was prospectively performed in 27 thalassemia major patients being prepared for HSCT. The area of red marrow and its percentage of the proximal femur were measured, and the presence of marrow hemosiderosis was assessed.

[Hepatic metastasis of human colon carcinoma: establishment of a nude mouse model and its magnetic resonance imaging].

Objective: To establish a nude mouse model mimicking hepatic metastasis of human colon carcinoma and study its magnetic resonance imaging (MRI) features and the quality of diffusion-weighted images (DWI).

Methods: Human colon carcinoma SW480 cells were inoculated subcutaneously ((1x10(7)/ml, 0.5 ml) in the costal regions of 2 nude mice, and after successful tumor formation, the generated tumors were harvested and cut into tissue blocks of 1 mm(3).

Magnetic resonance microneurography of rabbit sciatic nerve on a 1.5-T clinical MR system correlated with gross anatomy.

This study was performed to investigate the feasibility and accuracy of magnetic resonance (MR) microneurography of the rabbit sciatic nerve on a 1.5-T clinical MR system by correlation with the gross anatomy. The 3D T2-weighted imaging (3D-T2WI), 3D T2-weighted imaging plus spectral presaturation with inversion recovery (SPIR), and T1-weighted imaging (T1WI) of the sciatic nerve in ten rabbits were performed on a 1.

[Imaging and pathological features of gastrointestinal stromal tumors].

Objective: To investigate the imaging features and pathological manifestations of gastrointestinal stromal tumors (GISTs).

Methods: The imaging characteristics and pathological manifestations of 26 surgically treated patients with histologically confirmed GISTs were retrospectively analyzed.

Results: The tumors were found to originate from the small bowel (n=10), stomach (n=8), colon (n=6), mesentery (n=1) and omentum (n=1).

[Diffusion weighted imaging features of normal uterine cervix and cervical carcinoma].

Background & Objective: Magnetic resonance imaging (MRI) is a feasible method to detect, diagnose and stage cervical cancer. This study was to analyze the diffusion weighted imaging (DWI) features of normal uterine cervix and cervical carcinoma, and assess the values of DWI in diagnosis and monitor of cervical carcinoma after radiotherapy.

Methods: Routine MRI sequence and axial diffusion weighted sequence (b=800 s/mm2) were performed in 20 patients with cervical carcinoma and in 16 healthy women as control.

[Clinical significance of diffusion-weighted MRI with STIR-EPI in differential diagnosis of cervical lymph nodes].

Objective: To evaluate the feasibility and efficacy of a new MRI imaging method--diffusion weighted imaging (DWI) with short TI version recovery-echo planar imaging (STIR-EPI) sequence in differentiating benign cervical lymph nodes from malignant ones. METHODS Twenty nasopharyngeal carcinoma patients and fourteen volunteers received both conventional MRI and DWI with STIR-EPI. Ability of detecting lymph nodes between conventional MRI and STIR-EPI-DWI was compared, and the difference of apparent diffusion coefficient (ADC) value between metastatic lymph node and normal lymph node was analyzed.