Publications by authors named "Bhushan M"

Article Synopsis
  • - The study examines how metal implants in patients with cervix carcinoma affect treatment planning and dose delivery, by comparing two different radiotherapy plans for 11 patients with hip prostheses.
  • - Two treatment plans were designed: one with unrestricted beam entry (Plan_No_Res) and another restricted by the implant (Plan_exit_only); both plans were tested using a specialized phantom to measure dose accuracy.
  • - Results showed no significant dose differences between the two plans, although treatment time slightly increased, and measurement errors near the implant highlighted the need for improved methods to manage artifacts caused by metal in dosimetry.
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Recently, the utilization of metal halide perovskites in sensing and their application in environmental studies have reached a new height. Among the different metal halide perovskites, cesium lead halide perovskites (CsPbX; X = Cl, Br, and I) and composites have attracted great interest in sensing applications owing to their exceptional optoelectronic properties. Most CsPbX nanostructures and composites possess great structural stability, luminescence, and electrical properties for developing distinct optical and photonic devices.

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Tissue integrity is sensitive to temperature, tension, age, and is sustained throughout life by adaptive cell-autonomous or extrinsic mechanisms. Safeguarding the remarkably-complex architectures of neurons and glia ensures age-dependent integrity of functional circuits. Here, we report mechanisms sustaining the integrity of C.

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Introduction: Cerebral venous sinus thrombosis (CVST) is a rare and life-threatening condition that may be encountered during pregnancy and puerperium. The diagnosis of CVST is a challenge because of its varied presentation.

Case Report: A 28-year-old woman presented with headache, projectile vomiting, and generalized tonic-clonic seizures 10 days after delivery by cesarean section.

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Objective: To determine the feasibility, reliability, and acceptability of video teleconference (VTC)-based neuropsychological assessment using Addenbrooke's cognitive examination-III (ACE-III).

Methods: This study was performed from January 2022 to April 2022, during the third wave of the COVID-19 pandemic in India. We administered ACE-III using video-teleconferencing and compared the scores to face-to-face (FTF) testing for the eligible participants.

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In recent years, studies on the formulation of nanoemulsions have been the focus of attention due to their potential applicability in food, pharmaceuticals, cosmetics, and agricultural industries. Nanoemulsions can be formulated using ingredients approved by the Food and Drug Administration (FDA), which assures their safety profiles to a great extent. Bioactive compounds such as essential oils although have strong biological properties and antimicrobial compounds, their usage is restricted due to their high volatility, instability, and hydrophobic nature.

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Globally, the impact of the coronavirus disease 2019 (COVID-19) pandemic has been enormous and unrelenting with ∼6.9 million deaths and ∼765 million infections. This review mainly focuses on the recent advances and potentially novel molecular tools for viral diagnostics and therapeutics with far-reaching implications in managing the future pandemics.

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Thromboangiitis obliterans, or Buerger's disease, is a relatively rare nonatherosclerotic, segmental inflammatory and obliterative vascular disease that affects the small- and medium-sized arteries, veins, and nerves. In the acute phase, the lesion presents as an inflammatory, nonsuppurative panarteritis or panphlebitis with vascular thrombosis without necrosis. In the late stage of the disease, the thrombus becomes organized leading to varying degrees of recanalization and subsequent gangrene and amputation.

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Article Synopsis
  • The study investigates how different optimization techniques affect radiation treatment for patients with metallic hip implants using IMRT and VMAT methods.
  • A total of 16 patients were examined, comparing three sets of plans with variations in beam restrictions for radiation entry and exit around the implants.
  • Results showed that VMAT plans generally performed better than IMRT plans, especially when restricting beam entry, leading to improved dose distribution and fewer high-dose areas.
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Computer-aided detection using Deep Learning (DL) and Machine Learning (ML) shows tremendous growth in the medical field. Medical images are considered as the actual origin of appropriate information required for diagnosis of disease. Detection of disease at the initial stage, using various modalities, is one of the most important factors to decrease mortality rate occurring due to cancer and tumors.

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Introduction: The number of patients for carcinoma cervix with implanted hip prostheses has been increasing worldwide during the past several decades. Technological advancements are useful for delivering higher doses, i.e.

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Source Apportionment (SA) techniques are widely used for identifying key sources of air pollution, thereby providing critical inputs for policy measures. Positive Matrix Factorisation (PMF) (Paatero and Tapper, 1994) is a widely used SA technique. PMF uses the speciated concentration data (X) collected over several days and factorises it into source contribution (G) and source profile (F) matrices, albeit under positivity constraint.

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Aim: We aimed to evaluate the dosimetric influence of Acuros XB (AXB) dose-to-medium (D) and dose-to-water (D) reporting mode on carcinoma cervix using intensity-modulated radiation therapy (IMRT) and RapidArc (RA) technique.

Materials And Methods: A cohort of thirty patients cared for carcinoma cervix was retrospectively selected for the study. Plans were computed using analytical anisotropic algorithm (AAA), AXB-D, and AXB-D algorithms for dosimetric comparison.

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Aim: To validate the Acuros XB (AXB) algorithm in Eclipse treatment planning system (TPS) for RapidArc™ (RA) technique following the software upgrades.

Materials And Methods: A Clinac-iX (2300CD) linear accelerator and Eclipse TPS (Varian Medical System, Inc., Palo Alto, USA) was used for commissioning of AXB algorithm using a 6 megavolts photon beam.

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Background: Routinely, patient's planning scans are acquired after administration of iodinized contrast media but they will be treated in the absence of that. Similarly, high energy photons have a better penetrating power, while low energy photons will result in tighter dose distribution and negligible neutron contamination. The aim of the study was to investigate a suitable photon beam energy in the presence of intravenous contrast medium.

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The year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid pace to beat the pandemic. There is an increased need to comprehensively understand various aspects of the virus from detection to treatment options including drugs and vaccines for effective global management of the disease.

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Background: Acuros XB (AXB) may predict better rectal toxicities and treatment outcomes in cervix carcinoma. The aim of the study was to quantify the potential impact of AXB computations on the cervix radiotherapy using the RapidArc (RA ) technique as compared to anisotropic analytical algorithm (AA) computations.

Materials And Methods: A cohort of 30 patients previously cared for cervix carcinoma (stages II-IIIB) was selected for the present analysis.

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First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1-RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation.

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Background: The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluate the feasibility of different planning algorithms in the presence of high-density metallic implant in the treatment of patients with carcinoma cervix.

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Introduction: Human Salmonella infections have been classically distinguished into diseases caused by typhoidal and non-typhoidal salmonella (NTS). Typhiodal salmonella includes S. enterica serovars Typhi and Paratyphi that cause the systemic disease but are restricted to human infections, while NTS consists mainly of other serovars that predominantly cause self-limiting gastroenteritis in humans.

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Injectable platelet-rich fibrin (I-PRF) is a second generation, fully autologous, blood-derived biomaterial having three-dimensional fibrin meshwork, like that of a PRF clot, while retaining the fluid nature, just like platelet-rich plasma (PRP). Along with platelets and its growth factors, injectable PRF predominantly has collagen type-1, lymphocytes along with its growth factors. Preparation of injectable PRF is simple and requires minimal instrumentation and materials, making it a cost-effective product.

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Background: To evaluate the dosimetric impact of variable bladder filling on target and organ at risk (OARs) in cervical cancer patients undergoing chemoradiation. Forty consecutive patients with cervical cancer underwent radiotherapy planning as per the departmental protocol. All patients were asked to empty their bowel and bladder before simulation and catheterization was done.

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The methodology discussed in Lekinwala et al., 2020, hereinafter referred to as the 'parent article', is used to setup a nation-wide network for background PM measurement at strategic locations, optimally placing sites to obtain maximum regionally representative PM concentrations with minimum number of sites. Traditionally, in-situ PM measurements are obtained for several potential sites and compared to identify the most regionally representative sites [4], Wongphatarakul et al.

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Introduction: Aim of study is to investigate the effect of hip prosthesis on 6 and 15 MV photon beam energies.

Materials And Methods: Prosthesis was kept at the level of tray position. The measurements were done on Varian Clinac-iX linac.

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