Microbiological assessment of ready-to-eat foods and drinking water sources as a potential vehicle of bacterial pathogens in northern India.

Foodborne illnesses caused by the consumption of contaminated foods have frequent occurrences in developing countries. The incorporation of contaminated water in food processes, preparation, and serving is directly linked to several gastrointestinal infections. Keeping in view, this study was conducted to assess the microbial quality of both drinking water sources and commonly consumed fresh ready-to-eat (RTE) foods in the region.

To Evaluate the Effect of Vitamin B Complex on Wound Healing - A Clinical and Microbiological Study.

Background: The purpose of this study is to explore the effect of vitamin B complex supplementation following periodontal flap surgery on clinical and microbiological parameters.

Materials And Methods: A randomized controlled trial on 10 patients with periodontitis in split-mouth design was undertaken to find the effect of vitamin B complex supplementation with open flap debridement on periodontal wound healing. Multiplex polymerase chain reaction (PCR) for and was done using subgingival plaque samples at 0 and 90 day.

High-Precision Measurement of the Pu/Pu Isotope Ratio by TIMS.

With an aim to improve the precision of isotopic standards of special nuclear materials like uranium and plutonium, National Bureau of Standards (NBS) undertook the recertification of isotopic standards prepared between 1960 and 1970. In a recent initiative, Lawrence Livermore National Laboratory (LLNL) in collaboration with New Brunswick Laboratory Program Office (NBL PO) undertaken efforts to recertify SRM 946, SRM 947, and SRM 948. The primary goal of this drive is to lower the uncertainties associated with the isotopic compositions of plutonium standards.

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 The primary form of treatment for salivary gland cancer is surgical resection. Radiation therapy is used as adjuvant therapy in cases of aggressive tumours, currently patients with recurrent or metastatic cancer who are not suitable for surgery or radiation are most often treated with chemotherapy. PRISMA guidelines for systematic reviews were followed to evaluate salivary gland malignancies involving cytotoxic chemotherapy and biologic agents.

Amniotic membrane versus platelet-rich fibrin in treatment of gingival recession- a randomized control trial.

Objective: To determine the efficacy of latelet-rich fibrin (PRF) and Amniotic membrane (AM) along with the coronally advanced flap (CAF) technique in treating Miller's class I gingival recession (GR) defects.

Material And Methods: A total of 32 sites with Miller's class I GR defects were distributed into Group A (CAF + PRF, n = 16) and Group B (CAF + AM, n = 16). Clinical parameters like gingival index (GI), plaque index (PI), gingival bleeding index (GBI), gingival sulcus depth (GSD), relative attachment level (RAL), and gingival marginal level (GML) were measured at baseline and at 3, 6 and 9 months after surgical intervention.

Anaesthetic and Surgical Considerations in Post COVID-19 Patients Requiring Head and Neck Surgery.

As the cases of COVID-19 have declined, the number of patients who have recovered from the dreaded disease is reporting for elective or emergency surgeries. Surgical planning in patients who have recovered from COVD-19 requires special considerations because of the morbidity and mortality associated with the infection and its devastating after-effects. There is a distinct paucity of literature on guidelines and protocols to follow in the perioperative management of these patients.

Effect of LASER photobiomodulation on the cell viabilities of periodontal ligament fibroblasts of older and younger individuals - An study.

Background And Objectives: Fibroblasts form the major cell type of the periodontal ligament and most often studied for periodontal regeneration. The aim of the present study was to investigate the effects of photobiomodulation (PBM) on aged periodontal fibroblasts and compare the viability of periodontal fibroblasts of older and younger individuals.

Materials And Methods: A total of 32 patients were divided into four groups: A, B, C, and D.

Phase 1 study of cabozantinib in combination with topotecan-cyclophosphamide for patients with relapsed Ewing sarcoma or osteosarcoma.

Purpose: Phase 1 study assessing the safety and toxicity of cabozantinib in combination with topotecan and cyclophosphamide for relapsed osteosarcoma and Ewing sarcoma.

Methods: Oral cabozantinib (25 mg/m ) was administered daily for 21 (dose level 1) or 14 (dose level -1B) days. Topotecan (0.

Phase 2 trial of palbociclib and ganitumab in patients with relapsed Ewing sarcoma.

Background: Ewing sarcoma (EWS) is an aggressive sarcoma with few treatment options for patients with relapsed disease. Cyclin-dependent kinase 4 (CDK4) is a genomic vulnerability in EWS that is synergistic with IGF-1R inhibition in preclinical studies. We present the results of a phase 2 study combining palbociclib (CDK4/6 inhibitor) with ganitumab (IGF-1R monoclonal antibody) for patients with relapsed EWS.

Unusual case of Trigeminal Neuralgia Associated with Poland -Moebius Syndrome.

Moebius Syndrome is a rare congenital neurological condition characterized by paralysis of several cranial nerves, commonly the VI(Abducens) and VII(Facial) cranial nerves which causes lateral gaze strabismus and internal strabismus & classical mask like appearance respectively. Other cranial nerves such as V, VII, IX, X, XI, XII are rarely affected. Von Graefe and German neurologist Moebius (1888), after whom the syndrome was eventually named, provided the earliest descriptions of it.

Perception of the Educational Environment and Its Impact on the Academic Performance of Medical School Students: a Cross-Sectional Study.

To assess the perception of medical school students on their learning environment and to evaluate the association between their academic performance and perception. This was a cross-sectional study conducted in one public and one private medical school in Delhi and Tamil Nadu states of India, respectively, among 415 medical students using systematic random sampling. Dundee Ready Educational Environment Measure (DREEM) questionnaire was used to assess the perception of the educational environment.

Unraveling the paleo-marine signature in saline thermal waters of Cambay rift basin, Western India: Insights from geochemistry and multi isotopic (B, O and H) analysis.

Cambay rift basin is the only geothermal province in India that hosts several saline thermal water manifestations having EC values varying from 525 to 10,860 μS/cm. Various ionic ratios (Na/Cl, Br/Cl, Ca/(SO + HCO), SO/Cl) as well as boron isotopic composition (δB = 40.5 to 46 ‰) clearly ascribes the presence of fossil (relics of evaporated seawater) seawater as origin of increased salinity in the majority of thermal waters.

Kinesiologic Tape on Post Operative Swelling, Pain, Trismus in Zygomatico-Maxillary Complex Fracture after Orif: A Changing Tactics.

There has been always a need of new methods to control post operative complications in OMFS. A randomized prospective study was done to assess the effect of K tape on postoperative swelling, pain, trismus in Zygomatico-maxillary Complex (ZMC) fracture after open reduction with internal fixation using two point fixation. 30 patients of either gender undergoing ORIF for ZMC fracture using two point fixation of age group between 18 and 50 years were included in the study.

Compare the Efficacy of Open Reduction and Internal Fixation of Mandibular Fractures With and Without Use of Intra-Operative Inter-Maxillary Fixation.

Mandible fractures are regularly encountered by maxillofacial surgeons and various treatment protocols are available for the management of these fractures. The aim of study compares the efficacy of open reduction and internal fixation of mandibular fractures with and without use of intra-operative inter-maxillary fixation. Twenty patients between age group ranging l8-65 years who reported with single mandibular fracture in Dental college in India, during Oct 2012-March 2015 were the study subjects.

Assessment of Healing and Pain Response at Mandibular Third Molar Extraction Sites with and Without Pre- and PostOperative Photobiomodulation at Red and Near-Infrared Wavelengths: A Clinical Study.

Background: Photobiomodulation (PBM), formerly known as low-level laser therapy, has been successfully used for its anti-inflammatory and analgesic properties in postoperative care. It is also known to have a positive effect on healing and regeneration, at an appropriate power and wavelength.

Aim: The main objective was to assess the effect of preoperative as well a postoperative irradiation with low power of 100 milliwatts (mW) and 810-nanometer (nm) (near-infrared) and 660-nanometer(nm) (red) wavelengths on healing as well pain at mandibular third molar extraction sockets.

Assessment of gingival crevicular fluid levels of gamma glutamyl transferase in chronic periodontitis patients before and after non-surgical periodontal therapy: A clinico-biochemical study.

Objectives: Gamma-glutamyl transferase (GGT) enzyme is a routinely used diagnostic marker to detect various systemic diseases, elevation of which indicates destructive activity. Elevated GGT levels in GCF of destructive periodontal diseases hence can be expected. Hence, the aim of this study was to investigate if gamma glutamyl transferase would be a good indicator of on-going disease activity and to also assess the effect of non-surgical therapy on Gamma glutamyl transferase in gingival crevicular fluid of clinically healthy and chronic periodontitis patients.

Soft Skills and Psychosocial Counselling in COVID-19 Times: the Changing Tactics.

Introduction: As the COVID-19 pandemic is increasingly griping the world, it starts effecting the psychosocial health of the patients, health care workers, frontline workers and their dependents. The entire landscape of existing patient psychological counselling and management needs to be changed to avoid fear and misinformation about COVID-19.

Material And Methods: In this article, we have tried to summarize the rules, regulations and protocols in accordance with government guidelines along with practical implementation of counselling in management of psychological health condition of patients and frontline workers.

Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations.

Purpose: This was a multicenter, histology-agnostic, single-arm prospective phase II trial of therapeutic activity of everolimus, an oral mTORC1 inhibitor, in patients with advanced solid tumors that harbored / or mutations.

Patients And Methods: Patients with tumors with inactivating / or activating mutations identified in any Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory were eligible. Patients were treated with everolimus 10 mg once daily until disease progression or unacceptable toxicity.

Role of Telemedicine for Facio-Odontogenic Pain Management During COVID-19 Pandemic.

Introduction: As the COVID-19 pandemic is increasingly griping the world, the entire landscape of existing patient management needs to be changed to avoid spread of Corona virus. In cases of emergencies, there is no option other than getting in-person consultations with doctors. But, in non-emergency patients, telemedicine can serve as a boon.

Task-Specific Supported Liquid Membrane for Actinide Assay in Aqueous Streams by Thermal Ionization Mass Spectrometry.

Thermal ionization mass spectrometry is the most commonly used technique for the determination of Pu isotopic composition and concentration in complex matrices but involves multiple steps including sample pretreatment, removal of matrix, preconcentration of Pu, and loading on a rhenium filament for TIMS analysis. The present work reports the synthesis of the ,'-dioctyl-α-hydroxyacetamide (DOHA) functionalized supported liquid membrane that offered dual functions: (i) matrix elimination and/or preconcentration of actinides from complex aqueous samples and (ii) served as a loading substrate for TIMS analysis. The ligand composition in the membrane can be tuned aiming either for selective preconcentration of Pu from an aqueous matrix or for bulk removal of actinides.

Evaluation of Periodontal Status among Men Undergoing Infertility Treatment.

Aims: It has been estimated that >30% of male infertility cases are of idiopathic etiology. Recent studies revealed a positive connection between periodontal pockets and sperm submotility, which proposes that periodontitis may have a role in male infertility and inadequate semen quality. The aim of the present investigation was to inspect the relationship between male fertility parameters and the periodontal status of male patients attending treatment (IVF) clinic.

A Concerted Synchronous [2 + 2] Cycloreversion Repair Catalyzed by Two Electrons.

The current understanding of photoenzyme-catalyzed [2 + 2] cycloreversion repair of cyclobutane pyrimidine dimer (CPD) is that a photogenerated electron from the photolyase enzyme catalyzes the repair. This one-electron catalyzed repair is a sequential two-bond breaking cycloreversion of the cyclobutane center and involves a negative ion radical as an intermediate. Here, by resonantly capturing two exogenous low-energy electrons into the molecular field of a CPD, we show that the concerted synchronous two-bond breaking reaction, which is intermediate-free, and hence a safe repair, is feasible through two-electron catalysis.